001476591 000__ 04339cam\\22006137i\4500 001476591 001__ 1476591 001476591 003__ OCoLC 001476591 005__ 20231003174428.0 001476591 006__ m\\\\\o\\d\\\\\\\\ 001476591 007__ cr\cn\nnnunnun 001476591 008__ 230911s2023\\\\sz\a\\\\o\\\\\001\0\eng\d 001476591 019__ $$a1395885869$$a1396064820 001476591 020__ $$a9783031352058$$q(electronic bk.) 001476591 020__ $$a303135205X$$q(electronic bk.) 001476591 020__ $$z9783031352041 001476591 020__ $$z3031352041 001476591 0247_ $$a10.1007/978-3-031-35205-8$$2doi 001476591 035__ $$aSP(OCoLC)1396756674 001476591 040__ $$aGW5XE$$beng$$erda$$epn$$cGW5XE$$dEBLCP$$dYDX$$dOCLCO 001476591 049__ $$aISEA 001476591 050_4 $$aRS420 001476591 08204 $$a615.1/9$$223/eng/20230911 001476591 24500 $$aDrug discovery and design using natural products /$$cJorddy Neves Cruz, editor. 001476591 264_1 $$aCham, Switzerland :$$bSpringer,$$c2023. 001476591 300__ $$a1 online resource (xi, 542 pages) :$$billustrations 001476591 336__ $$atext$$btxt$$2rdacontent 001476591 337__ $$acomputer$$bc$$2rdamedia 001476591 338__ $$aonline resource$$bcr$$2rdacarrier 001476591 500__ $$aIncludes index, 001476591 5050_ $$aPart I. Genesis of research projects that use natural products to design new drugs - - Part II. Initial processes for identifying and extracting compounds: isolation and identifying these structures -- Part III. Screening of compounds using molecular modeling approaches: optimization of natural compounds using In silico methods -- Part IV. Synthesis and encapsulation of compounds of natural origin -- Part V. Identification of molecular targets of natural molecules and biological potential. 001476591 506__ $$aAccess limited to authorized users. 001476591 520__ $$aHistorically, natural products have great relevance for the development of new drugs. Natural molecules, in addition to directly providing new compounds with different therapeutic functions have provided scaffolds and a great diversity of structures that serve as inspiration for the design and discovery of new drugs. The great structural complexity and the significant number of natural compounds that can be obtained and their advantages also present some historical problems that need to be overcome. Issues such as difficulty in isolation, difficulty in synthesizing compounds found in nature in the laboratory, screening to evaluate the biological properties of these compounds, and structural optimization to enhance the pharmacological properties of biomolecules; are some of the main difficulties encountered in research with natural products and in the design/discovery of new medicines. Therefore, this book addresses the great scientific advances that provide practical solutions to using natural products to develop new drugs. We address topics related to the genesis of research projects that use natural products to design new drugs. We address the discovery of new species, initial processes for identification and extraction of compounds, isolation and identification of these structures, techniques, and advances in vitro and in vivo methods that support the discovery of new natural drugs, synthesis of new compounds from natural molecules, in silico optimization processes of potentially promising compounds. 001476591 588__ $$aOnline resource; title from PDF title page (SpringerLink, viewed September 5, 2023). 001476591 650_0 $$aDrugs$$xDesign. 001476591 650_0 $$aNatural products. 001476591 650_6 $$aMédicaments$$xConception. 001476591 650_6 $$aProduits naturels. 001476591 655_0 $$aElectronic books. 001476591 7001_ $$aCruz, Jorddy Neves,$$eeditor. 001476591 77608 $$iPrint version:$$aCruz, Jorddy Neves$$tAspiration Based Decision Support Systems$$dCham : Springer,c2023$$z9783031352041 001476591 852__ $$bebk 001476591 85640 $$3Springer Nature$$uhttps://univsouthin.idm.oclc.org/login?url=https://link.springer.com/10.1007/978-3-031-35205-8$$zOnline Access$$91397441.1 001476591 909CO $$ooai:library.usi.edu:1476591$$pGLOBAL_SET 001476591 980__ $$aBIB 001476591 980__ $$aEBOOK 001476591 982__ $$aEbook 001476591 983__ $$aOnline 001476591 994__ $$a92$$bISE