001478519 000__ 05014nam\a22007575i\4500 001478519 001__ 1478519 001478519 003__ DE-B1597 001478519 005__ 20231026034943.0 001478519 006__ m\\\\\o\\d\\\\\\\\ 001478519 007__ cr\un\nnnunnun 001478519 008__ 221201t20092002mau\\\\\o\\d\z\\\\\\eng\d 001478519 020__ $$a9780674039445 001478519 0247_ $$a10.4159/9780674039445$$2doi 001478519 035__ $$a(DE-B1597)588899 001478519 035__ $$a(OCoLC)1322124368 001478519 040__ $$aDE-B1597$$beng$$cDE-B1597$$erda 001478519 0410_ $$aeng 001478519 044__ $$amau$$cUS-MA 001478519 050_4 $$aQH491 ǂb K387 2002eb 001478519 072_7 $$aSCI008000$$2bisacsh 001478519 08204 $$a570.1 001478519 084__ $$aWB 4000$$2rvk 001478519 1001_ $$aKeller, Evelyn Fox, $$eauthor.$$4aut$$4http://id.loc.gov/vocabulary/relators/aut 001478519 24510 $$aMaking Sense of Life :$$bExplaining Biological Development with Models, Metaphors, and Machines /$$cEvelyn Fox Keller. 001478519 264_1 $$aCambridge, MA : $$bHarvard University Press, $$c[2009] 001478519 264_4 $$c©2002 001478519 300__ $$a1 online resource (400 p.) 001478519 336__ $$atext$$btxt$$2rdacontent 001478519 337__ $$acomputer$$bc$$2rdamedia 001478519 338__ $$aonline resource$$bcr$$2rdacarrier 001478519 347__ $$atext file$$bPDF$$2rda 001478519 50500 $$tFrontmatter -- $$tContents -- $$tPreface -- $$tIntroduction -- $$tPART ONE Models: Explaining Development without the Help of Genes -- $$tIntroduction -- $$tCHAPTER ONE Synthetic Biology and the Origin of Living Form -- $$tCHAPTER TWO Morphology as a Science of Mechanical Forces -- $$tCHAPTER THREE Untimely Births of a Mathematical Biology -- $$tPART TWO Metaphors: Genes and Developmental Narratives -- $$tIntroduction -- $$tCHAPTER FOUR Genes, Gene Action, and Genetic Programs -- $$tCHAPTER FIVE Taming the Cybernetic Metaphor -- $$tCHAPTER SIX Positioning Positional Information -- $$tPART THREE Machines: Understanding Development with Computers, Recombinant DNA, and Molecular Imaging -- $$tIntorduction -- $$tCHAPTER SEVEN The Visual Culture of Molecular Embryology -- $$tCHAPTER EIGHT New Roles for Mathematical and Computational Modeling -- $$tCHAPTER NINE Synthetic Biology Redux-Computer Simulation and Artificial Life -- $$tConclusion: Understanding Development -- $$tNotes -- $$tReferences -- $$tIndex 001478519 506__ $$aAccess limited to authorized users. 001478519 520__ $$aWhat do biologists want? If, unlike their counterparts in physics, biologists are generally wary of a grand, overarching theory, at what kinds of explanation do biologists aim? How will we know when we have "made sense" of life? Such questions, Evelyn Fox Keller suggests, offer no simple answers. Explanations in the biological sciences are typically provisional and partial, judged by criteria as heterogeneous as their subject matter. It is Keller's aim in this bold and challenging book to account for this epistemological diversity--particularly in the discipline of developmental biology. In particular, Keller asks, what counts as an "explanation" of biological development in individual organisms? Her inquiry ranges from physical and mathematical models to more familiar explanatory metaphors to the dramatic contributions of recent technological developments, especially in imaging, recombinant DNA, and computer modeling and simulations. A history of the diverse and changing nature of biological explanation in a particularly charged field, Making Sense of Life draws our attention to the temporal, disciplinary, and cultural components of what biologists mean, and what they understand, when they propose to explain life. 001478519 538__ $$aMode of access: Internet via World Wide Web. 001478519 546__ $$aIn English. 001478519 5880_ $$aDescription based on online resource; title from PDF title page (publisher's Web site, viewed 01. Dez 2022) 001478519 650_7 $$aSCIENCE / Life Sciences / Biology.$$2bisacsh 001478519 655_0 $$aElectronic books 001478519 77308 $$iTitle is part of eBook package:$$dDe Gruyter$$tHarvard University Press eBook Package Backlist 2000-2013$$z9783110442205 001478519 852__ $$bebk 001478519 85640 $$3De Gruyter$$uhttps://univsouthin.idm.oclc.org/login?url=https://www.degruyter.com/isbn/9780674039445$$zOnline Access 001478519 909CO $$ooai:library.usi.edu:1478519$$pGLOBAL_SET 001478519 912__ $$a978-3-11-044220-5 Harvard University Press eBook Package Backlist 2000-2013$$c2000$$d2013 001478519 912__ $$aEBA_BACKALL 001478519 912__ $$aEBA_EBACKALL 001478519 912__ $$aEBA_EBKALL 001478519 912__ $$aEBA_EEBKALL 001478519 912__ $$aEBA_ESTMALL 001478519 912__ $$aEBA_PPALL 001478519 912__ $$aEBA_STMALL 001478519 912__ $$aGBV-deGruyter-alles 001478519 912__ $$aPDA12STME 001478519 912__ $$aPDA13ENGE 001478519 912__ $$aPDA18STMEE 001478519 912__ $$aPDA5EBK 001478519 980__ $$aBIB 001478519 980__ $$aEBOOK 001478519 982__ $$aEbook 001478519 983__ $$aOnline