001480506 000__ 04694nam\a22007575i\4500 001480506 001__ 1480506 001480506 003__ DE-B1597 001480506 005__ 20231026034750.0 001480506 006__ m\\\\\o\\d\\\\\\\\ 001480506 007__ cr\un\nnnunnun 001480506 008__ 221201t20162016mau\\\\\o\\d\z\\\\\\eng\d 001480506 020__ $$a9780674972506 001480506 0247_ $$a10.4159/9780674972506$$2doi 001480506 035__ $$a(DE-B1597)479652 001480506 035__ $$a(OCoLC)984651014 001480506 040__ $$aDE-B1597$$beng$$cDE-B1597$$erda 001480506 0410_ $$aeng 001480506 044__ $$amau$$cUS-MA 001480506 072_7 $$aSCI017000$$2bisacsh 001480506 1001_ $$aFantuzzi, Giamila, $$eauthor.$$4aut$$4http://id.loc.gov/vocabulary/relators/aut 001480506 24510 $$aBody Messages :$$bThe Quest for the Proteins of Cellular Communication /$$cGiamila Fantuzzi. 001480506 264_1 $$aCambridge, MA : $$bHarvard University Press, $$c[2016] 001480506 264_4 $$c©2016 001480506 300__ $$a1 online resource (250 p.) 001480506 336__ $$atext$$btxt$$2rdacontent 001480506 337__ $$acomputer$$bc$$2rdamedia 001480506 338__ $$aonline resource$$bcr$$2rdacarrier 001480506 347__ $$atext file$$bPDF$$2rda 001480506 50500 $$tFrontmatter -- $$tContents -- $$tForeword -- $$tPrologue -- $$t1. The Medium Is the Message, the Message Is the Change -- $$t2. Doing Research: Ways to Study Body Messages -- $$t3. Evolution of Message Discovery: The Interleukin-1 Family -- $$t4. Achieving Balance: Pro- and Anti-Inflammatory Mediators -- $$t5. Traps and Diversions: Cytokine Decoys -- $$t6. Between Inflammation and Metabolism: The Acute- Phase Response -- $$t7. The Fat Revolution: Adipokines 189 Epilogue -- $$tAbbreviations -- $$tNotes -- $$tAcknowledgments -- $$tIndex 001480506 506__ $$aAccess limited to authorized users. 001480506 520__ $$aWhether classified as regulators of inflammation, metabolism, or other physiological functions, a distinctive set of molecules enables the human body to convey information from one cell to another. An in-depth primer on the molecular mediators that coordinate complex bodily processes, Body Messages provides fresh insight into how biologists first identified this special class of molecules and the consequences of their discovery for modern medicine. Focusing on proteins that regulate inflammation and metabolism-including the cytokines and adipokines at the core of her own research-Giamila Fantuzzi examines the role body messages play in the physiology of health as well as in the pathology of various illnesses. Readers are introduced to different ways of conceptualizing biomedical research and to the advantages and pitfalls associated with identifying molecules beginning with function or structure. By bringing together areas of research usually studied separately, Fantuzzi stresses the importance of investigating the body as a whole and affirms the futility of trying to separate basic from clinical research. Drawing on firsthand interviews with researchers who made major contributions to the field, Body Messages illustrates that the paths leading to scientific discovery are rarely direct, nor are they always the only routes available. 001480506 538__ $$aMode of access: Internet via World Wide Web. 001480506 546__ $$aIn English. 001480506 5880_ $$aDescription based on online resource; title from PDF title page (publisher's Web site, viewed 01. Dez 2022) 001480506 650_7 $$aSCIENCE / Life Sciences / Cell Biology.$$2bisacsh 001480506 655_0 $$aElectronic books 001480506 7001_ $$aLandecker, Hannah, $$econtributor.$$4ctb$$4https://id.loc.gov/vocabulary/relators/ctb 001480506 77308 $$iTitle is part of eBook package:$$dDe Gruyter$$tHarvard University Press Complete eBook-Package 2016$$z9783110638585 001480506 852__ $$bebk 001480506 85640 $$3De Gruyter$$uhttps://univsouthin.idm.oclc.org/login?url=https://www.degruyter.com/isbn/9780674972506$$zOnline Access 001480506 909CO $$ooai:library.usi.edu:1480506$$pGLOBAL_SET 001480506 912__ $$a978-3-11-063858-5 Harvard University Press Complete eBook-Package 2016$$b2016 001480506 912__ $$aEBA_BACKALL 001480506 912__ $$aEBA_CL_MDPM 001480506 912__ $$aEBA_EBACKALL 001480506 912__ $$aEBA_EBKALL 001480506 912__ $$aEBA_ECL_MDPM 001480506 912__ $$aEBA_EEBKALL 001480506 912__ $$aEBA_ESTMALL 001480506 912__ $$aEBA_PPALL 001480506 912__ $$aEBA_STMALL 001480506 912__ $$aGBV-deGruyter-alles 001480506 912__ $$aPDA12STME 001480506 912__ $$aPDA13ENGE 001480506 912__ $$aPDA18STMEE 001480506 912__ $$aPDA5EBK 001480506 980__ $$aBIB 001480506 980__ $$aEBOOK 001480506 982__ $$aEbook 001480506 983__ $$aOnline