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Table of Contents
Intro
Foreword
Conflict of Interest
Endophthalmitis
How to Use This Book
Contents
Chapter 1: Endophthalmitis: Classification and Most Frequently Reported Organisms
Chapter 2: Differential Diagnosis of Endophthalmitis
Toxic Anterior Segment Syndrome (Fig. 2.1)
Retained Lens Fragments (Figs. 2.2 and 2.3)
Flare-Up of Pre-existing Uveitis
Vitreous Hemorrhage
Retinoblastoma
Uveal Melanoma
Intravitreal Triamcinolone Acetonide
Viral Retinitis
Noninfectious Inflammation from Intravitreal Injections
Brolucizumab-Related Intraocular Inflammation
Drug-Associated Uveitis (a Rare Cause of Pseudoendophthalmitis)
Chapter 3: Diagnosis of Endophthalmitis: Clinical Presentation, Pathology, Microbiology, and Echography
Clinical Presentations
Microbiology
How to Perform TAP and Inject
Intravitreal Antimicrobial Injection
Results of Anterior Chamber TAP Versus Vitreous TAP
Culture Media
Other Testing
Echography
Chapter 4: Acute-Onset Endophthalmitis: Clinical Categories, Incidence Rates, Signs/Symptoms, Risk Factors, Microbiology, Treatment, and Follow-Up
Acute-Onset Post-Operative Endophthalmitis Following Cataract Surgery
Incidence
Signs/Symptoms
Risk Factors
Microbial Isolates
Initial Management of Acute-Onset Post-Operative Endophthalmitis
Intravitreal antimicrobials (Fig. 4.5)
Follow-Up Management of Acute-Onset Post-Operative Endophthalmitis (Fig. 4.6)
First Morning after Initial Treatment
Two to Three Days after Initial Treatment
Acute-Onset Endophthalmitis Following Pars Plana Vitrectomy
Incidence
Signs/Symptoms
Risk Factors (Table 4.1)
Microbial Isolates
Endophthalmitis after Pars Plana Vitrectomy for Vitreous Floaters (Fig. 4.7)
Initial Management of Acute-Onset Endophthalmitis Following Vitrectomy
Follow-Up Management in Patients with Acute-Onset Endophthalmitis Following Vitrectomy
First Morning after Initial Treatment
Two to Three Days after Initial Treatment
Post-Traumatic Endophthalmitis
Incidence
Signs/Symptoms
Risk Factors
Microbial Isolates
Initial Management of Post-Traumatic Endophthalmitis
Follow-Up Management in Patients with Post-Traumatic Endophthalmitis
First Morning after Initial Treatment
Two to Three Days after Initial Treatment
Endophthalmitis Associated with Intravitreal Injection
Incidence
Signs/Symptoms of Endophthalmitis after Intravitreal Injections
Risk Factors
Microbial Isolates
Initial Management of Endophthalmitis Associated with Intravitreal Injection
Follow-Up Management in Patients with Endophthalmitis Associated with Intravitreal Injection
First Morning after Initial Treatment
Two to Three Days after Initial Treatment
Additional Discussion Points
Vitreous TAP Versus AC TAP/Paracentesis
Controversies in Care
Foreword
Conflict of Interest
Endophthalmitis
How to Use This Book
Contents
Chapter 1: Endophthalmitis: Classification and Most Frequently Reported Organisms
Chapter 2: Differential Diagnosis of Endophthalmitis
Toxic Anterior Segment Syndrome (Fig. 2.1)
Retained Lens Fragments (Figs. 2.2 and 2.3)
Flare-Up of Pre-existing Uveitis
Vitreous Hemorrhage
Retinoblastoma
Uveal Melanoma
Intravitreal Triamcinolone Acetonide
Viral Retinitis
Noninfectious Inflammation from Intravitreal Injections
Brolucizumab-Related Intraocular Inflammation
Drug-Associated Uveitis (a Rare Cause of Pseudoendophthalmitis)
Chapter 3: Diagnosis of Endophthalmitis: Clinical Presentation, Pathology, Microbiology, and Echography
Clinical Presentations
Microbiology
How to Perform TAP and Inject
Intravitreal Antimicrobial Injection
Results of Anterior Chamber TAP Versus Vitreous TAP
Culture Media
Other Testing
Echography
Chapter 4: Acute-Onset Endophthalmitis: Clinical Categories, Incidence Rates, Signs/Symptoms, Risk Factors, Microbiology, Treatment, and Follow-Up
Acute-Onset Post-Operative Endophthalmitis Following Cataract Surgery
Incidence
Signs/Symptoms
Risk Factors
Microbial Isolates
Initial Management of Acute-Onset Post-Operative Endophthalmitis
Intravitreal antimicrobials (Fig. 4.5)
Follow-Up Management of Acute-Onset Post-Operative Endophthalmitis (Fig. 4.6)
First Morning after Initial Treatment
Two to Three Days after Initial Treatment
Acute-Onset Endophthalmitis Following Pars Plana Vitrectomy
Incidence
Signs/Symptoms
Risk Factors (Table 4.1)
Microbial Isolates
Endophthalmitis after Pars Plana Vitrectomy for Vitreous Floaters (Fig. 4.7)
Initial Management of Acute-Onset Endophthalmitis Following Vitrectomy
Follow-Up Management in Patients with Acute-Onset Endophthalmitis Following Vitrectomy
First Morning after Initial Treatment
Two to Three Days after Initial Treatment
Post-Traumatic Endophthalmitis
Incidence
Signs/Symptoms
Risk Factors
Microbial Isolates
Initial Management of Post-Traumatic Endophthalmitis
Follow-Up Management in Patients with Post-Traumatic Endophthalmitis
First Morning after Initial Treatment
Two to Three Days after Initial Treatment
Endophthalmitis Associated with Intravitreal Injection
Incidence
Signs/Symptoms of Endophthalmitis after Intravitreal Injections
Risk Factors
Microbial Isolates
Initial Management of Endophthalmitis Associated with Intravitreal Injection
Follow-Up Management in Patients with Endophthalmitis Associated with Intravitreal Injection
First Morning after Initial Treatment
Two to Three Days after Initial Treatment
Additional Discussion Points
Vitreous TAP Versus AC TAP/Paracentesis
Controversies in Care