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001480843 001__ 1480843
001480843 003__ OCoLC
001480843 005__ 20231031003311.0
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001480843 019__ $$a1396974213
001480843 020__ $$a9783031260988$$q(electronic bk.)
001480843 020__ $$a3031260988$$q(electronic bk.)
001480843 020__ $$z303126097X
001480843 020__ $$z9783031260971
001480843 0247_ $$a10.1007/978-3-031-26098-8$$2doi
001480843 035__ $$aSP(OCoLC)1397569558
001480843 040__ $$aEBLCP$$beng$$cEBLCP$$dGW5XE$$dYDX
001480843 049__ $$aISEA
001480843 050_4 $$aQP363.5
001480843 08204 $$a612.64018$$223/eng/20230927
001480843 1001_ $$aDonkelaar, H. J. ten$$q(Hendrik Jan),$$d1946-
001480843 24510 $$aClinical neuroembryology :$$bdevelopment and developmental disorders of the human central nervous system /$$cHans J. ten Donkelaar, Martin Lammens, Akira Hori.
001480843 250__ $$a3rd ed.
001480843 260__ $$aCham :$$bSpringer,$$c2023.
001480843 300__ $$a1 online resource (926 p.)
001480843 500__ $$a3: Causes of Congenital Malformations
001480843 504__ $$aIncludes bibliographical references and index.
001480843 5050_ $$aIntro -- Preface -- Preface to the Second Edition -- Preface to the First Edition -- Contents -- Contributors -- 1: Overview of the Development of the Human Brain and Spinal Cord -- 1.1 Introduction -- 1.2 Major Stages in the Development of the Human Brain and Spinal Cord -- 1.3 The First Three Weeks of Development -- 1.3.1 Implantation -- 1.3.2 Gastrulation -- 1.3.3 Folding of the Embryo -- 1.4 Neurulation -- 1.5 Development of the Spinal Cord -- 1.6 Pattern Formation of the Brain -- 1.7 Early Development of the Brain -- 1.7.1 Imaging of the Embryonic Brain -- 1.7.2 Neuromeres
001480843 5058_ $$a1.7.3 The Ganglionic Eminences -- 1.8 Foetal Development of the Brain -- 1.8.1 The Cerebellum -- 1.8.2 The Cerebral Cortex -- 1.8.3 Cerebral Commissures -- 1.8.4 Imaging of the Foetal Brain -- 1.9 Development of the Meninges and Choroid Plexuses -- 1.10 Development of the Blood Supply of the Brain -- 1.11 Development of Fibre Tracts and Their Myelination -- 1.11.1 Development of Fibre Tracts -- 1.11.2 Development of Myelination -- 1.11.3 Prenatal Motor Behaviour -- 1.12 The Foetal Connectome -- References -- 2: Mechanisms of Development -- 2.1 Introduction -- 2.2 Neural Induction
001480843 5058_ $$a2.2.1 The Spemann-Mangold Organizer -- 2.2.2 The Molecular Basis of Neural Induction -- 2.2.3 Polarity and the Establishment of the Neuraxis -- 2.2.4 Neural Induction in Amniote Embryos -- 2.2.5 Specific Pathways for Head Induction -- 2.3 Cell Lineage Studies and Fate Mapping -- 2.4 Pattern Formation -- 2.4.1 Regionalization of the Forebrain -- 2.4.2 The Intrathalamic Limiting Zone -- 2.4.3 The Midbrain-Hindbrain Boundary Organizer -- 2.4.4 Segmentation of the Hindbrain -- 2.5 Specification of Cell Fate -- 2.5.1 Specification of Cell Fate in the Spinal Cord
001480843 5058_ $$a2.5.2 Specification of Cell Fate in the Hindbrain -- 2.5.3 Specification of Cell Fate in the Midbrain -- 2.5.4 Specification of Cell Fate in the Diencephalon -- 2.5.5 Specification of Cell Fate in the Hypothalamus -- 2.5.6 Specification of Cell Fate in the Telencephalon -- 2.5.7 The Transcriptomic Approach to the Developing Central Nervous System -- 2.6 Neurogenesis, Gliogenesis and Migration -- 2.6.1 Neurogenesis: Primary and Secondary Proliferative Compartments -- 2.6.2 Gliogenesis -- 2.6.3 Migration -- 2.7 Axon Outgrowth and Guidance -- 2.7.1 Pioneer Fibres
001480843 5058_ $$a2.7.2 The Guidance of Axons to Their Targets -- 2.7.3 Axon Guidance at Choice Points -- 2.7.4 Commissure Formation -- 2.7.5 Formation of Thalamocortical and Corticofugal Projections -- 2.7.6 Formation of Topographic Maps -- 2.7.7 Genetic Approaches of Neural Circuits in Mice -- 2.7.7.1 Molecular Odorant Map -- 2.7.7.2 Molecular Retinotopic Map -- 2.7.7.3 Molecular Somatosensory Map -- 2.7.7.4 Molecular Tonotopic Map -- 2.7.7.5 Molecular Taste Maps -- 2.7.7.6 Molecular Vestibular Maps -- 2.7.8 Human Disorders of Axon Guidance -- 2.8 Programmed Cell Death -- References
001480843 506__ $$aAccess limited to authorized users.
001480843 520__ $$aThis book provides a comprehensive overview of the development of the human central nervous system (CNS) in the context of its many developmental disorders due to genetic, environmental and hypoxic/ischaemic causes. The book contains three general, introductory chapters in which an overview of the development of the human brain and spinal cord, a summary of mechanisms of development as obtained in experimental studies in various invertebrates and vertebrates, and an overview of the causes of congenital malformations are presented. The developmental disorders of the human brain and spinal cord are presented in a regional, more or less segmental way, starting with neurulation and neural tube defects, and ending with developmental disorders of the cerebral cortex. These chapters are abundantly illustrated in colour with carefully chosen clinical case studies with imaging data, and when available, postmortem verification of the developmental disorders involved. In the third edition, more emphasis has been given to the developmental ontology based on the prosomeric approach, and fetal development. Prenatal diagnosis by ultrasound, MRI and DTI, and classifications of developmental disorders have been updated. A number of new Clinical Cases have been included. Several new co-authors participate in various chapters. The book is intended for advanced medical students, and all those clinicians working with children and adults with developmental disorders of the CNS. Unique to the book is the integration of data from human embryology, experimental and molecular findings in mice in particular, imaging and developmental neuropathology.
001480843 588__ $$aOnline resource; title from PDF title page (SpringerLink, viewed September 27, 2023).
001480843 650_0 $$aDevelopmental neurobiology.
001480843 650_0 $$aEmbryology, Human.
001480843 650_0 $$aCentral nervous system$$xDiseases.
001480843 655_0 $$aElectronic books.
001480843 7001_ $$aLammens, Martin.
001480843 7001_ $$aHori, Akira$$c(Neuropathologist)
001480843 77608 $$iPrint version:$$aten Donkelaar, Hans J.$$tClinical Neuroembryology$$dCham : Springer International Publishing AG,c2023$$z9783031260971
001480843 852__ $$bebk
001480843 85640 $$3Springer Nature$$uhttps://univsouthin.idm.oclc.org/login?url=https://link.springer.com/10.1007/978-3-031-26098-8$$zOnline Access$$91397441.1
001480843 909CO $$ooai:library.usi.edu:1480843$$pGLOBAL_SET
001480843 980__ $$aBIB
001480843 980__ $$aEBOOK
001480843 982__ $$aEbook
001480843 983__ $$aOnline
001480843 994__ $$a92$$bISE