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001480864 019__ $$a1396974693$$a1405398195
001480864 020__ $$a9783031351396$$q(electronic bk.)
001480864 020__ $$a3031351398$$q(electronic bk.)
001480864 020__ $$z303135138X
001480864 020__ $$z9783031351389
001480864 0247_ $$a10.1007/978-3-031-35139-6$$2doi
001480864 035__ $$aSP(OCoLC)1397572758
001480864 040__ $$aEBLCP$$beng$$cEBLCP$$dGW5XE$$dYDX$$dOCLCO$$dSFB
001480864 049__ $$aISEA
001480864 050_4 $$aRC112
001480864 08204 $$a616.9$$223/eng/20230925
001480864 24500 $$aSex and gender differences in infection and treatments for infectious diseases /$$cSabra L. Klein, Craig W. Roberts, editors.
001480864 250__ $$a2nd ed.
001480864 260__ $$aCham :$$bSpringer,$$c2023.
001480864 300__ $$a1 online resource (281 p.).
001480864 336__ $$atext$$btxt$$2rdacontent
001480864 337__ $$acomputer$$bc$$2rdamedia
001480864 338__ $$aonline resource$$bcr$$2rdacarrier
001480864 4901_ $$aCurrent Topics in Microbiology and Immunology ;$$vv. 441
001480864 500__ $$a2.4 Animal Models of Sex Differences in Influenza Pathogenesis
001480864 504__ $$aBibliography -- The Influence of Sex Hormones and X Chromosome in Immune Responses -- 1 Introduction -- 2 Sex Hormone Signaling and X Chromosome Dosage Effects -- 2.1 Sex Steroid Hormones Signaling -- 2.2 X Chromosome Gene Dosage and X Chromosome Inactivation Escape -- 3 Biological Role of Sex-Linked Factors in Autoimmunity -- 3.1 Sex Hormone and X Chromosome Regulation in Organ-Specific Autoimmunity: The Example of Multiple Sclerosis. -- 3.2 Sex Hormones and X Chromosome Effects in Systemic Autoimmunity (SLE)
001480864 5050_ $$aIntro -- Contents -- Genetics of Sex Differences in Immunity -- 1 Evolutionary Perspective -- 2 Sex Chromosomes -- 2.1 X Chromosome Inactivation -- 2.2 Immune-Related Genes on the Sex Chromosomes -- 2.3 Sex Chromosome Abnormalities and the Immune System -- 3 Experimental Models for Studying the Sex Effect on Immunity -- 3.1 Four Core Genotypes Mouse Model -- 3.2 Human Cell Lines with Sex Chromosome Aberrations -- 3.3 Additional Mouse Models -- 4 Female-Specific States and Their Immune Consequences -- 4.1 Pregnancy as a Graft -- 4.2 Microchimerism in Fetal Cells -- 5 Concluding Remarks
001480864 5058_ $$a4 Sex Differences in Allergic Asthma: A Prominent Role of Sex Steroid Hormone Signaling -- 4.1 Sex Bias in Asthma Prevalence and Severity -- 4.2 Impact of Sex Hormones in Type 2 Mediated Allergic Airway Inflammation -- 5 Biological Sex Influences Natural Immunity to Neonatal Pathogens and Cancer -- 5.1 Sex-Biased Dimorphism in Bloodstream Infections: The Role of Estrogens/Peritoneal Macrophages/B-1 Cells Axis -- 5.2 Sex Dimorphism in Solid Tumor Control: From Innate to Acquired Immunity -- References -- Sex Differences in HIV Infection -- 1 Introduction -- 2 Sex Differences in HIV Acquisition
001480864 5058_ $$a3 Sex Differences in HIV Pathogenesis -- 4 Immune Mechanisms Underlying Sex Differences -- 5 Sex Differences in ART-Treated Disease -- 6 Summary -- References -- Effects of Biological Sex and Pregnancy on SARS-CoV-2 Pathogenesis and Vaccine Outcomes -- 1 Sex Differences in Viral Pathogenesis -- 2 Sex Differences in SARS-CoV-2 Pathogenesis -- 2.1 SARS-CoV-2 Entry, Replication, and Transmission -- 2.2 Development of Innate and Adaptive Immune Responses -- 2.3 Sex Differences in Post-Acute Sequelae SARS-CoV-2 Infection (PASC) -- 2.4 Comorbidities, Sex Difference, and COVID-19
001480864 5058_ $$a2.5 Role of Sex Steroids -- 2.6 Role of Genetic Variations -- 3 Pregnancy and SARS-CoV-2 Pathogenesis -- 4 Sex Differences in COVID-19 Vaccine Outcomes -- 4.1 Immunogenicity -- 4.2 Effectiveness -- 4.3 Vaccine Reactogenicity -- 5 Pregnancy and COVID-19 Vaccines -- 6 Conclusions and Future Directions -- References -- Biological Sex and Pregnancy Affect Influenza Pathogenesis and Vaccination -- 1 Introduction -- 2 Sex Differences in Influenza Pathogenesis -- 2.1 Seasonal Influenza Epidemics -- 2.2 Outbreaks of Avian Influenza -- 2.3 Influenza A Virus Pandemics
001480864 506__ $$aAccess limited to authorized users.
001480864 520__ $$aThis fully revised and significantly expanded second edition examines sex and gender differences in the immune system's response to bacterial, viral, and parasitic infections. The volume discusses both common and distinct molecular mechanisms that mediate these differences and illustrates how responses to vaccines may differ between the sexes and in pregnant individuals. Special emphasis is placed on the interplay between hormones and the immune system in the pathogenesis of HIV, SARS-CoV-2, influenza, malaria, tuberculosis, and amebiasis. This second edition includes completely rewritten chapters as well as all new contents. This book is intended for researchers in academia and industry as well as clinicians in the fields of microbiology, immunology, and pharmacology. By expanding knowledge in sex and gender medicine as a basis for developing personalized treatment strategies, the book contributes to UN Sustainable Development Goals 3 (health and well-being) and 5 (gender equality).
001480864 588__ $$aOnline resource; title from PDF title page (SpringerLink, viewed September 25, 2023).
001480864 650_6 $$aMaladies infectieuses$$xFacteurs sexuels.
001480864 650_6 $$aMaladies infectieuses$$xTraitement$$xFacteurs sexuels.
001480864 650_6 $$aMaladies$$xFacteurs sexuels.
001480864 650_0 $$aCommunicable diseases$$xSex factors.$$0(DLC)sh 85025392
001480864 650_0 $$aCommunicable diseases$$xTreatment$$xSex factors.$$0(DLC)sh 85025392
001480864 650_0 $$aSex factors in disease.$$0(DLC)sh 85120613
001480864 655_0 $$aElectronic books.
001480864 7001_ $$aKlein, Sabra L.
001480864 7001_ $$aRoberts, Craig W.
001480864 77608 $$iPrint version:$$aKlein, Sabra L.$$tSex and Gender Differences in Infection and Treatments for Infectious Diseases$$dCham : Springer International Publishing AG,c2023$$z9783031351389
001480864 830_0 $$aCurrent topics in microbiology and immunology ;$$vv. 441.
001480864 852__ $$bebk
001480864 85640 $$3Springer Nature$$uhttps://univsouthin.idm.oclc.org/login?url=https://link.springer.com/10.1007/978-3-031-35139-6$$zOnline Access$$91397441.1
001480864 909CO $$ooai:library.usi.edu:1480864$$pGLOBAL_SET
001480864 980__ $$aBIB
001480864 980__ $$aEBOOK
001480864 982__ $$aEbook
001480864 983__ $$aOnline
001480864 994__ $$a92$$bISE