The embryologic basis of craniofacial structure : developmental anatomy, evolutionary design, and clinical applications / Michael H. Carstens, editor.
Carstens, Michael H.
2023
QM535
Available Online

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Title
The embryologic basis of craniofacial structure : developmental anatomy, evolutionary design, and clinical applications / Michael H. Carstens, editor.
ISBN
9783031156366 (electronic bk.)
3031156366 (electronic bk.)
3031156358
9783031156359
DOI
https://doi.org/10.1007/978-3-031-15636-6
Publication Details
Cham : Springer, 2023.
Language
English
Description
1 online resource (1756 p.)
Item Number
10.1007/978-3-031-15636-6 doi
Call Number
QM535
Dewey Decimal Classification
611.91
Summary
Focusing on the anatomy of the head and neck, this book begins at the cellular level of development, detailing bone, muscle, blood supply, and innervation along the way. It illustrates the origin of each tissue structure to aid in making prognoses beyond the surface deformation, offering typical issues seen in the craniofacial region, for example. Written by a pediatric Craniofacial plastic surgeon and intended for clinicians and residents in the areas of plastic surgery, ENT, maxillofacial surgery, and orthodontistry, this book is the first of its kind to focus so intently on evolution of the craniofacial structure. It is neatly broken up into two distinct sections. The first section is meant for readers to gain a fundamental understanding of the development of craniofacial structures, from embryo onward, relying on the concepts of the Neuromeric Theory. The chapters in the first section of the book trace the development of the typical patient. The second section offers clinical examples of how the Neuromeric Theory can be used to repair or reconstruct various regions of the head and neck. Craniofacial clefts, including cleft lip and palate, ocular hypotelorism, anencephaly, craniosynostosis and more are detailed. Understanding the formation of the tissue structures involved in any given genetic deformation or anomaly enables the clinician to provide a more satisfying outcome for the patient, both structurally and aesthetically. New and current therapeutic options are explored and supported through original illustrations and photographs to aid in determining the best treatment for each individual patient. Embryological Principles of Craniofacial Structure bridges the gap between introductory books on the basic anatomy of the head and neck and the detailed understanding required for corrective surgery of craniofacial defects.
Note
Migration Patterns of Neural Crest
Includes index.
Access Note
Access limited to authorized users.
Source of Description
Online resource; title from PDF title page (SpringerLink, viewed October 13, 2023).
Added Author
Carstens, Michael H.
Available in Other Form
The Embryologic Basis of Craniofacial Structure
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Intro
Foreword
Foreword
The Open Sesame for Craniofacial Biology
Foreword
Foreword
Foreword
Foreword
A Unified Theory of Developmental Field Repair
Foreword
Foreword
Commentary-Jean-Claude Talmant
Foreword
Preface
What Brings You to Open This Book?
The Open Sesame of Structure
Curtains and a Surgical Innovation
The 4Ds
Sojourn in Basic Science
Stem Cell Stimulus
Qualifications
Why Should You Read This Book?
Acknowledgments
Contents
About the Contributors
1: Neuromeric Organization of the Head and Neck
Introduction

Definitions
Zoologic Abbreviations
Developmental Fields: Lessons from the Common Labiomaxillary Cleft
The 4-D Theory of Cleft Formation
The Biologic Significance of Relapse
Beyond Descriptive Embryology: Developmental Fields and the Functional Matrix
Neurovascular Mapping of Developmental Fields: Nasomaxillary Model
Neuromeres and Neuromeric Coding
Neuromeres: The Clinical Significance of the Neuromeric Map
Craniofacial Neural Crest
Craniofacial Mesoderm: Extraembryonic Versus Intraembryonic
The Little Appreciated Hypoblast

How Segmentation of the Mesoderm Matches that of the Neural Tube
Molecular Basis of Segmentation
Introduction to Homeotic Genes
Clinical Significance
Craniocaudal Pattern Formation
Neuromeric Basis of Neural Crest "Migration" and Fate
Anterior Prosencephalic Neural Fold: Nonneural Ectoderm
Posterior Prosencephalic Neural Fold: Neural Crest (PNC)
Mesencephalic Neural Crest (MNC)
Rhombencephalic Neural Crest (RNC)
Spatial Reassignment of Nonneural Ectoderm
Timing of Neural Crest Migration
Fate of the Neural Crest: The Role of Epithelial "Programming"

Ectomeres and Endomeres: A Final Note
Summary
References
2: Anatomy of Mesenchyme and the Pharyngeal Arches
Introduction
Three Caveats
Anatomy of Craniofacial Mesoderm
Paraxial Mesoderm: Somitomeres and Somites
Three Types of Cranium
Second Iteration of Cranial Mesoderm: The Pharyngeal Arches
Fate of Pharyngeal Arch PAM (Table 2.2)
The Mammalian System of Pharyngeal Arches
Evolutionary Considerations
Vascularization of the Pharyngeal Arches: Nutritional Basis of Derivatives
Hypothetical Model of Vascular Development
Fate of Non-pharyngeal Arch PAM

Blood Supply to the Face: An Overview
Summary of Circulations as Determined by Neural Crest
In Sum
Aortic Arch Precursors
Birth and Death of the Stapedial Artery System
Internal Maxillo-Mandibular Arterial Axis Summarized
Anatomy of Craniofacial Neural Crest
Building Blocks of the Face
Forebrain: Prosencephalic Neural Crest (PNC) > Fronto-Orbito-Nasal Skin
Midbrain: Mesencephalic Neural Crest (MNC) > Upper Face
Hindbrain: Rhombencephalic Neural Crest (RNC) > Midface
Developmental Fields Can Be Lumped into Three Groups: A + B + C

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