@article{1481282,
      recid = {1481282},
      author = {Yan, Qin.},
      title = {Targeting lysine demethylases in cancer and other human  diseases /},
      publisher = {Springer,},
      address = {Cham :},
      pages = {1 online resource (187 p.).},
      year = {2023},
      note = {4.4 Physiological Functions of KDM3A},
      abstract = {This book provides a comprehensive summary of our current  knowledge on lysine demethylases, a class of epigenetic  regulators. It takes the reader on an exciting journey  spanning the past two decades, starting from the initial  discovery and characterization of these enzymes and leading  up to the development of their small molecule modulators.  These modulators have shown promise in clinical trials and  hold great potential to improve patient outcomes. The book  captures the progress made in this field and highlights the  significant advancements that have paved the way for  potential therapeutic applications. The book covers a wide  range of topics, spanning both basic biology and clinical  implications associated with lysine demethylases. It offers  a comprehensive historical and conceptual framework for the  discovery and characterization of similar epigenetic  enzymes or modulators. Chapter one serves as an  introductory overview, providing insights into the general  characteristics and functions of lysine demethylases. In  subsequent chapters, specifically chapters two to eight,  each major family of lysine demethylases is individually  explored in depth. By providing in-depth insights into the  functional aspects of these enzymes, the book allows  readers to grasp their significance in regulating cellular  processes and influencing pathogenesis. Moreover, the book  goes beyond fundamental knowledge and also explores the  development of diagnostic and therapeutic strategies  related to lysine demethylases. It highlights the potential  for utilizing these enzymes as therapeutic targets for the  treatment of various diseases, including cancer and  infectious diseases. Additionally, the book highlights  future directions aimed at further unraveling the roles of  lysine demethylases and translating these findings into the  clinic.},
      url = {http://library.usi.edu/record/1481282},
      doi = {https://doi.org/10.1007/978-3-031-38176-8},
}