Modern keratoplasty : surgical techniques and indications / Jorge L. Alió, Jorge L. Alió del Barrio, editors.
Alió, Jorge L.; Barrio, Jorge L. Alió del.
2023
RE336
Available Online

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Title Modern keratoplasty : surgical techniques and indications / Jorge L. Alió, Jorge L. Alió del Barrio, editors.
ISBN 9783031324086 (electronic bk.)
3031324080 (electronic bk.)
3031324072
9783031324079
DOI https://doi.org/10.1007/978-3-031-32408-6
Publication Details Cham : Springer, 2023.
Language English
Description 1 online resource (521 p.).
Item Number 10.1007/978-3-031-32408-6 doi
Call Number RE336
Dewey Decimal Classification 617.719059
Summary Keratoplasty techniques have evolved in the last 15 years into a variety of forms, which have diversified the previous monographic presence of the penetrating keratoplasty technique. The development of anterior lamellar graft (DALK), and posterior lamellar graft (DSAEK), makes an important change in the approach to lamellar surgery. Later on, the appearance of DMEK and superficial lamellar keratectomy broadened the spectrum. Today, intralamellar surgery has evolved with a number of techniques that involve stromal enhancement with biologically active or acellular corneal laminas from donors, customized lenticles from SMILE surgeries or customized by corneal topography, and more recently, corneal regeneration of the stroma by advanced techniques using mesenchymal stem cells. This book offers a comprehensive overview of modern keratoplasty techniques, the technology, surgical skills, and outcomes. It highlights the practical uses of keratoplasty for all cornea surgeons and anterior segment surgeons. The book is divided into sections, each covering a specific type of keratoplasty, including chapters on innovations within each surgery type. The goal of this book is to unify all recent knowledge about the different keratoplasty techniques and outcomes, creating a one-stop resource for ophthalmaolgy surgeons. Modern Keratoplasty is a must-have resource for corneal specialists and surgeons, anterior segment surgeons, refractive surgeons, cataract surgeons, residents, fellows, and corneal researchers.
Note 4: Management of the Vascularized Cornea Before Corneal Graft Surgery: Fine-Needle Diathermy and Inhibition of VEGF
Includes index.
Access Note Access limited to authorized users.
Source of Description Online resource; title from PDF title page (SpringerLink, viewed October 12, 2023).
Added Author Alió, Jorge L.
Barrio, Jorge L. Alió del.
Series Essentials in ophthalmology.
Available in Other Form Modern Keratoplasty
Linked Resources Online Access
Record Appears in Online Resources > Ebooks
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Intro
Preface
Preface
References
Acknowledgments
Contents
1: Introduction: Current Status of Modern Corneal Transplantation-Success, Failures and Turning Points
Introduction
Modern Modalities of Corneal Transplantations
Success, Failures and Complications of Modern Corneal Transplants
Complications of Corneal Transplants That Affect the Outcome
Graft Failure Modalities
Ad. 1. Frequency and Main Causes of Corneal Graft Anatomical Failure
Anatomical Failure in the Different Types of Corneal Grafts
Penetrating Keratoplasty

Deep Anterior Lamellar Keratoplasty
Endothelial Keratoplasty
Ad. 2
Functional Outcomes of Corneal Graft Procedures
Anatomical Outcomes After Regraft
Functional Outcomes After Regraft
Survival Rate of Corneal Graft
Conclusion: Real Success Rate of Modern Corneal Transplantation Procedures
References
Suggested Reading
Part I: Preparing the Patient
2: Modern Eye Banking: Preservation, Type of Tissues, and Selection
Introduction
Donor's Screening and Tissue Collection
Preservation Techniques
Moist Chamber Preservation
Cryopreservation

Hypothermic Storage
Organ Culture Preservation
Type of Tissues
Penetrating Keratoplasty
Anterior Lamellar Keratoplasties
Posterior Lamellar Keratoplasties
Prestripped, Precut and Preloaded Tissues in Eye Banks
Amniotic Membrane and Scleral Patches
Tissue Selection
Microbiological Testing
Morphological Examination: Slit-Lamp Biomicroscopy
Endothelial Evaluation: Inverted Light or Specular Microscopy
Sterile Donor Tomography
Detection of Cornea Guttata in the Eye Bank

Benefits of a Highly-Structured Quality Management System (QMS) by Example of the LIONS Eye Bank Saar-Lor-Lux, Trier/Westpfalz
Future Perspectives
References
3: Risk Classification and Management of Corneal Grafts, Human Leukocyte Antigen Matching, and Options for Immunosuppression Therapy
Introduction
Risk Stratification
Risk Factors
Primary Diagnosis
Previous Transplantation
Glaucoma
Active Inflammation
Herpetic Infection
Neovascularization
Atopy
Aphakia
Age
Limbal Stem Cell Deficiency
Additional Factors

Mitigation Strategies for Corneal Graft Rejection
Role of Lymphangiogenesis
Anti-angiogenic and Lymphangiogenic Therapy
Histocompatibility Matching
Strategies for Immunosuppression
Topical Therapy
Steroids
Cyclosporine
Tacrolimus
Systemic Therapy
Cyclosporine
Mycophenolate
Mycophenolate vs. Cyclosporine
Tacrolimus
Selecting Immunosuppression According to Risk Stratification
Special Considerations for Limbal Stem Cell Transplantation
Conclusion
References
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