001481305 000__ 06002cam\\22005177a\4500 001481305 001__ 1481305 001481305 003__ OCoLC 001481305 005__ 20231031003331.0 001481305 006__ m\\\\\o\\d\\\\\\\\ 001481305 007__ cr\un\nnnunnun 001481305 008__ 231002s2023\\\\si\\\\\\o\\\\\000\0\eng\d 001481305 019__ $$a1402025037 001481305 020__ $$a9789819917822$$q(electronic bk.) 001481305 020__ $$a9819917824$$q(electronic bk.) 001481305 020__ $$z9819917816 001481305 020__ $$z9789819917815 001481305 0247_ $$a10.1007/978-981-99-1782-2$$2doi 001481305 035__ $$aSP(OCoLC)1401094541 001481305 040__ $$aYDX$$beng$$cYDX$$dEBLCP$$dGW5XE 001481305 049__ $$aISEA 001481305 050_4 $$aRD641 001481305 08204 $$a617.477$$223/eng/20231013 001481305 24500 $$aUncommon ulcers of the extremities /$$cAjay K. Khanna, Satyendra Kumar Tiwary, editors. 001481305 260__ $$aSingapore :$$bSpringer,$$c2023. 001481305 300__ $$a1 online resource 001481305 5050_ $$aIntro -- Preface -- Contents -- Editors and Contributors -- About the Editors -- Contributors -- 1: Approach to a Case of Ulcer of Extremity -- 1.1 Prevalence -- 1.2 Relevant Points of Interest -- 1.3 Common Ulcerations Causes (Table 1.1) -- 1.4 Step-Wise Approach -- 1.5 Conclusion -- References -- 2: Hypertensive/Martorell Ulcer -- 2.1 Introduction -- 2.2 Pathogenesis -- 2.3 Clinical Presentation -- 2.4 Differential Diagnosis -- 2.5 Diagnosis -- 2.5.1 Diagnostic Criteria -- 2.6 Histopathological Diagnosis -- 2.7 Management -- 2.8 Skin Grafting -- 2.9 Pain Management 001481305 5058_ $$a2.10 General Measures -- 2.11 Management of Residual Wounds -- 2.12 Prognosis -- 2.13 Clinical Pearls -- 3: Rheumatoid Ulcers -- 3.1 Introduction -- 3.2 Epidemiology of Rheumatoid Limb Ulcers -- 3.3 Pathogenesis -- 3.3.1 Vasculitis and Inflammation -- 3.3.2 Differential Load Distribution -- 3.3.3 Associated Conditions -- 3.3.4 Iatrogenic -- 3.3.5 Impaired Healing -- 3.4 Clinical Features -- 3.4.1 Vasculitic Ulcers of the Extremities -- 3.4.2 Pyoderma Gangrenosum -- 3.5 Diagnosis -- 3.6 Management -- 3.6.1 Local Wound Care -- 3.6.2 Coverage for Secondary Infections 001481305 5058_ $$a3.6.3 Systemic Immunosuppression -- 3.6.4 Management of Pyoderma Gangrenosum -- 3.7 Conclusion -- References -- 4: Ulcers in Systemic Sclerosis -- 4.1 Introduction -- 4.1.1 Systemic Sclerosis: Definition and Prevalence -- 4.2 Diagnostic Criteria of Systemic Sclerosis -- 4.2.1 Ulcers in Systemic Sclerosis -- 4.3 Pathogenesis of Vascular Disease in Systemic Sclerosis -- 4.3.1 Pathogenesis of Ulcers -- 4.3.2 Ulcers over the Sites of Calcinosis -- 4.4 Clinical Features -- 4.5 Investigations -- 4.6 Management -- 4.6.1 Lifestyle Changes -- 4.6.2 Drug Treatment 001481305 5058_ $$a4.6.3 Prostanoids (Level of Evidence: Meta-Analysis) -- 4.6.4 Endothelin Receptor-1 Antagonists (Level of Evidence: Meta-Analysis) -- 4.6.5 Phosphodiesterase Type-5 Inhibitors (Level of Evidence: Meta-Analysis) -- 4.6.6 Calcium Channel Blockers (Level of Evidence: Randomized Controlled Trial) -- 4.6.7 Combination Therapy (Level of Evidence: Case Report) -- 4.6.8 Other Drug Therapies that Have Been Explored -- 4.6.8.1 Statins (Level of Evidence: Randomized Controlled Trial) -- 4.6.8.2 Anticoagulant and Antiplatelet Agents (Level of Evidence: Randomized Controlled Trial) 001481305 5058_ $$a4.6.9 Surgical Strategies -- 4.6.9.1 General Approach -- 4.6.9.2 Sympathectomy and Injection of Botulinum Toxin (Level of Evidence: Retrospective Case Series and Case Series) -- 4.6.10 Prognosis -- References -- 5: Livedoid Vasculopathy: Clinical, Histopathological, and Therapy Evaluation -- 5.1 Introduction -- 5.2 Our Casuistic -- 5.3 Methods -- 5.4 Results -- 5.5 Discussion -- 5.6 Hallmarks of the Literature -- 5.7 Conclusions -- References -- 6: Ulcers in Hypercoagulable States -- 6.1 Introduction -- 6.2 General Pathogenesis of Cutaneous Ulcers in Hypercoagulable States 001481305 506__ $$aAccess limited to authorized users. 001481305 520__ $$aThe book covers all uncommon ulcers of the extremities which remain a difficult diagnosis for clinicians most of the times. A variety of causes like metabolic, infective, rheumatoid, drug induced or inflammation may lead to ulcerations. Diagnosis of these ulceration is difficult as these diseases are systemic, and treatment is carried out by physicians but ulcers are managed by the surgeons. Any lacunae or gap in assessment or work-up may lead to failure in diagnosis and increased morbidity. This book provides a systematic and step wise approach to the differential diagnosis of every possible uncommon ulcers in the extremities with detailed work-up, flow chart and summary. The book is systematically designed to serve the purpose of covering every possible uncommon ulcer with elaborate clinical presentation in the background of etiology and pathogenesis with risk factors included investigations and treatment with medical, surgical options well discussed as per the requirement. The book includes illustrations, flow diagrams, images, charts and tables. The book provides every information clinically relevant and useful about the uncommon ulcers and serves as a complete resource for general surgeons, vascular surgeons, plastic surgeons, orthopedic surgeons, surgical trainees, family physicians. It may also be useful for podiatrists, phlebologists, radiologists, cardiologists, nephrologists, neurologists, wound care nurses, physicians and primary care workers. . 001481305 588__ $$aOnline resource; title from PDF title page (SpringerLink, viewed October 13, 2023). 001481305 650_0 $$aUlcers. 001481305 650_0 $$aLeg$$xUlcers. 001481305 650_0 $$aArm$$xUlcers. 001481305 655_0 $$aElectronic books. 001481305 77608 $$iPrint version: $$z9819917816$$z9789819917815$$w(OCoLC)1372392542 001481305 852__ $$bebk 001481305 85640 $$3Springer Nature$$uhttps://univsouthin.idm.oclc.org/login?url=https://link.springer.com/10.1007/978-981-99-1782-2$$zOnline Access$$91397441.1 001481305 909CO $$ooai:library.usi.edu:1481305$$pGLOBAL_SET 001481305 980__ $$aBIB 001481305 980__ $$aEBOOK 001481305 982__ $$aEbook 001481305 983__ $$aOnline 001481305 994__ $$a92$$bISE