Liquorpheresis : cerebrospinal fluid filtration to treat CNS conditions / Manuel Menéndez González.
Menéndez González, Manuel, author.
2023
QP375
Available Online

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Title Liquorpheresis : cerebrospinal fluid filtration to treat CNS conditions / Manuel Menéndez González.
Author Menéndez González, Manuel, author.
ISBN 9783031434822 (electronic bk.)
303143482X (electronic bk.)
9783031434815
3031434811
DOI https://doi.org/10.1007/978-3-031-43482-2
Published Cham : Springer, 2023.
Language English
Description 1 online resource (vi, 68 pages)
Item Number 10.1007/978-3-031-43482-2 doi
Call Number QP375
Dewey Decimal Classification 612.8/042
Summary This book provides an overview of emerging CSF management systems that filter or clear cerebrospinal fluid (CSF) as a therapeutic approach for several CNS conditions. While the term "liquorpheresis" most accurately refers to extracorporeal procedures that filter CSF (similar to plasmapheresis), this book covers any method based on devices that -either alone or in combination with drugs- can clear CSF or enhance its turnover, which in turn dilutes toxins. The book begins with an overview of CSF anatomy and physiology, followed by a discussion of the role of CSF clearance and flow dysfunction in various CNS conditions. The next section describes the different CSF management systems and procedures that are currently available or under development. The book then reviews the potential applications of these systems for treating subarachnoid hemorrhage, CNS infections, meningeal carcinomatosis, autoimmune encephalitis, polyradiculomyelitis, and neurodegenerative diseases. Finally, a chapter discusses future advances in liquorpheresis systems and applications. This book is intended for clinicians, neuro-researchers, academics, and students who are interested in the development and application of CSF management systems. It is also relevant to the medical device industry, particularly those that develop apheresis and CSF management devices, and the drug-delivery industry.
Bibliography, etc. Note Includes bibliographical references.
Access Note Access limited to authorized users.
Source of Description Online resource; title from PDF title page (SpringerLink, viewed October 11, 2023).
Available in Other Form Print version: 9783031434815
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Anatomy and Physiology
The four layers of meninges
The BBB
The cerebrospinal fluid (CSF) and the Interstitial fluid (ISF)
Introduction to liquorpheresis
Clearing the CSF as a therapeutic strategy in neurodegenerative diseases
Definitions of procedures, including a historical perspective
Systems and procedures
Types of procedures and systems
Classification and definitions of the different types of procedures for mechanical filtration of the CSF
The mechanism of action
The regime of usage
The implantability
The power for CSF flow
The CSF filtrating or neutralizing method
Applications and industry
Multiple sclerosis, autoimmune encephalitis, and polyradiculomyelitis
Meningeal carcinomatosis and leptomeningeal metastases
Infectious diseases
Viral encephalitis and viral myelitis
Bacterial meningoencephalitis
Fungal meningitis and fungal encephalitis
Brain aging and neurodegenerative diseases
Future advances in liquorpheresis systems and applications
New technical developments
New applications.

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