001481708 000__ 04864nam\a22008775i\4500 001481708 001__ 1481708 001481708 003__ DE-B1597 001481708 005__ 20231108092454.0 001481708 006__ m\\\\\o\\d\\\\\\\\ 001481708 007__ cr\un\nnnunnun 001481708 008__ 231108t20132013mau\\\\\o\\d\z\\\\\\eng\d 001481708 019__ $$a(OCoLC)840439752 001481708 020__ $$a9780674067196 001481708 0247_ $$a10.4159/harvard.9780674067196$$2doi 001481708 035__ $$a(DE-B1597)178014 001481708 035__ $$a(OCoLC)819325471 001481708 040__ $$aDE-B1597$$beng$$cDE-B1597$$erda 001481708 0410_ $$aeng 001481708 044__ $$amau$$cUS-MA 001481708 072_7 $$aMED078000$$2bisacsh 001481708 08204 $$a613.04244$$221 001481708 1001_ $$aJasienska, Grazyna,$$eauthor.$$4aut$$4http://id.loc.gov/vocabulary/relators/aut 001481708 24514 $$aThe Fragile Wisdom :$$bAn Evolutionary View on Women's Biology and Health /$$cGrazyna Jasienska. 001481708 264_1 $$aCambridge, MA :$$bHarvard University Press,$$c[2013] 001481708 264_4 $$c©2013 001481708 300__ $$a1 online resource (298 p.) :$$b19 line illustrations, 3 tables 001481708 336__ $$atext$$btxt$$2rdacontent 001481708 337__ $$acomputer$$bc$$2rdamedia 001481708 338__ $$aonline resource$$bcr$$2rdacarrier 001481708 347__ $$atext file$$bPDF$$2rda 001481708 50500 $$tFrontmatter --$$tContents --$$tIntroduction: Why It Is So Difficult to Be Perfectly Healthy --$$t1 If Reproductive Hormones Are So Important, Why Is There So Much Variation? --$$t2 Coevolution of Biology and Culture: Agriculture and Selection for High Levels of Estrogen --$$t3 You Are What You Eat . . . as a Fetus --$$t4 The French Paradox: Did Child Welfare Reduce the Risk of Heart Disease? --$$t5 Intergenerational Echoes of Slavery --$$t6 The Price of Reproduction --$$t7 The Ultimate Test of the Costs of Reproduction: Life Span --$$t8 Evolutionary Past and Modern Diet --$$t9 Evolution and Physical Activity --$$t10 Evolutionary Trade- Offs and Culture --$$t11 Fallacies of Philanthropy --$$t12 Fixing Genes versus Fixing Lifestyles --$$tConclusion: Is Our Physiology Obsolete? --$$tReferences --$$tAcknowledgments --$$tIndex 001481708 506__ $$aAccess limited to authorized users. 001481708 520__ $$aSo many women who do everything right to stay healthy still wind up with breast cancer, heart disease, or osteoporosis. In The Fragile Wisdom, Grazyna Jasienska provides an evolutionary perspective on the puzzle of why disease prevention among women is so frustratingly difficult. Modern women, she shows, are the unlucky victims of their own bodies' conflict of interest between reproductive fitness and life-long health. The crux of the problem is that women's physiology has evolved to facilitate reproduction, not to reduce disease risk. Any trait-no matter how detrimental to health in the post-reproductive period-is more likely to be preserved in the next generation if it increases the chance of giving birth to offspring who will themselves survive to reproductive age. To take just one example, genes that produce high levels of estrogen are a boon to fertility, even as they raise the risk of breast cancer in mothers and their daughters. Jasienska argues that a mismatch between modern lifestyles and the Stone Age physiology that evolution has bequeathed to every woman exacerbates health problems. She looks at women's mechanisms for coping with genetic inheritance and at the impact of environment on health. Warning against the false hope gene therapy inspires, Jasienska makes a compelling case that our only avenue to a healthy life is prevention programs informed by evolutionary understanding and custom-fitted to each woman's developmental and reproductive history. 001481708 538__ $$aMode of access: Internet via World Wide Web. 001481708 546__ $$aIn English. 001481708 5880_ $$aDescription based on online resource; title from PDF title page (publisher's Web site, viewed 30. Aug 2021) 001481708 650_7 $$aMEDICAL / Public Health.$$2bisacsh 001481708 655_0 $$aElectronic books 001481708 77308 $$iTitle is part of eBook package:$$dDe Gruyter$$tE-BOOK GESAMTPAKET / COMPLETE PACKAGE 2013$$z9783110317350$$oZDB-23-DGG 001481708 77308 $$iTitle is part of eBook package:$$dDe Gruyter$$tE-BOOK PACKAGE MEDICINE 2013$$z9783110317305$$oZDB-23-DME 001481708 77308 $$iTitle is part of eBook package:$$dDe Gruyter$$tE-BOOK PAKET MEDIZIN 2013$$z9783110317299$$oZDB-23-DMD 001481708 77308 $$iTitle is part of eBook package:$$dDe Gruyter$$tHUP eBook-Package Backlist 2000-2013 (Canada)$$z9783110756067 001481708 77308 $$iTitle is part of eBook package:$$dDe Gruyter$$tHarvard University Press eBook Package Backlist 2000-2013$$z9783110442205 001481708 852__ $$bebk 001481708 85640 $$3De Gruyter$$uhttps://univsouthin.idm.oclc.org/login?url=https://www.degruyter.com/isbn/9780674067196$$zOnline Access 001481708 909CO $$ooai:library.usi.edu:456585$$pGLOBAL_SET 001481708 912__ $$a978-3-11-044220-5 Harvard University Press eBook Package Backlist 2000-2013$$c2000$$d2013 001481708 912__ $$a978-3-11-075606-7 HUP eBook-Package Backlist 2000-2013 (Canada)$$b2013 001481708 912__ $$aEBA_BACKALL 001481708 912__ $$aEBA_CL_MDPM 001481708 912__ $$aEBA_EBACKALL 001481708 912__ $$aEBA_EBKALL 001481708 912__ $$aEBA_ECL_MDPM 001481708 912__ $$aEBA_EEBKALL 001481708 912__ $$aEBA_ESTMALL 001481708 912__ $$aEBA_PPALL 001481708 912__ $$aEBA_STMALL 001481708 912__ $$aGBV-deGruyter-alles 001481708 912__ $$aPDA12STME 001481708 912__ $$aPDA13ENGE 001481708 912__ $$aPDA18STMEE 001481708 912__ $$aPDA5EBK 001481708 912__ $$aZDB-23-DGG$$b2013 001481708 912__ $$aZDB-23-DMD$$b2013 001481708 912__ $$aZDB-23-DME$$b2013 001481708 980__ $$aBIB 001481708 980__ $$aEBOOK 001481708 982__ $$aEbook 001481708 983__ $$aOnline