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001482394 001__ 1482394
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001482394 019__ $$a1402244267
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001482394 020__ $$a981996878X$$q(electronic bk.)
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001482394 0247_ $$a10.1007/978-981-99-6878-7$$2doi
001482394 035__ $$aSP(OCoLC)1402816988
001482394 040__ $$aEBLCP$$beng$$cEBLCP$$dGW5XE$$dYDX$$dEBLCP$$dYDX$$dOCLCO$$dOCLCF
001482394 049__ $$aISEA
001482394 050_4 $$aQD96.M3$$bK56 2023
001482394 08204 $$a543/.65$$223/eng/20231023
001482394 1001_ $$aKim, Moon-Ju.
001482394 24510 $$aLaser desorption ionization mass spectrometry based on nanophotonic structure /$$cMoon-Ju Kim.
001482394 260__ $$aSingapore :$$bSpringer,$$c2023.
001482394 300__ $$a1 online resource (107 p.).
001482394 4901_ $$aSpringer theses
001482394 500__ $$a"Doctoral Thesis accepted by Yonsei University, Seoul, Korea (Republic of)."
001482394 504__ $$aIncludes bibliographical references.
001482394 5050_ $$aIntro -- Supervisor's Foreword -- Acknowledgements -- Contents -- 1 Introduction -- 1.1 Overview -- 1.2 Motivation and Outline -- References -- 2 Backgrounds -- 2.1 Organic Matrix-Assisted Laser Desorption Ionization (MALDI)-MS -- 2.2 Nanostructure-Based Laser Desorption Ionization (LDI)-MS -- 2.3 Research Trends in Developing LDI-Active Nanophotonic Structure -- References -- 3 Synergistic Effect of the Hybrid of Au Nanoislands on TiO2 Nanowires (Au-TNW) in Laser Desorption and Ionization -- 3.1 Introduction -- 3.2 Experimental Methods -- 3.3 Results and Discussion
001482394 5058_ $$a3.3.1 Fabrication and Characterization of Au-TNW Nanohybrid -- 3.3.2 LDI-MS Analysis Results of Immunosuppressive Drugs -- 3.3.3 Mechanistic Insights into the Synergistic Ion Production -- 3.4 Summary -- References -- 4 In Situ Surface Reconstruction-Driven Desorption and Ionization Enhancement in Nanoporous Au-Modified TiO2 Nanowires Hybrid (npAu-TNW) -- 4.1 Introduction -- 4.2 Experimental Methods -- 4.3 Results and Discussion -- 4.3.1 Fabrication and Characterization of npAu-TNW Nanohybrid -- 4.3.2 Origin of the Enhancement in Desorption and Ionization
001482394 5058_ $$a4.3.3 Application of npAu-TNW Nanohybrid for Neurotransmitter LDI-MS Analysis -- 4.4 Summary -- References -- 5 Photothermal Structural Dynamics of Au Nanofurnace-Functionalized ZnO Nanotube (AuNI-ZNT) for In Situ Enhancement in Desorption and Ionization -- 5.1 Introduction -- 5.2 Experimental Methods -- 5.3 Results and Discussion -- 5.3.1 Fabrication and Characterization of AuNI-ZNT Nanohybrid -- 5.3.2 Strategies for Improving Desorption and Ionization Efficiencies -- 5.3.3 LDI-MS Performance Enhancement Based on AuNI-ZNT Nanohybrid -- 5.4 Summary -- References
001482394 5058_ $$a6 In Situ Evolution of Atomic Defect and Piezoelectricity in Graphitic Carbon Nitride Nanosheet (G-C3N4 NS) by Short Laser Pulse for the Ionization in Mass Spectrometry -- 6.1 Introduction -- 6.2 Experimental Methods -- 6.3 Results and Discussion -- 6.3.1 Fabrication and Characterization of G-C3N4 NS -- 6.3.2 Influence of Nanosecond Laser-Pulse-Driven Shock Pressure on LDI-MS Performance -- 6.3.3 G-C3N4 NS as Efficient LDI-MS Substrate -- 6.4 Summary -- References -- 7 Conclusions
001482394 506__ $$aAccess limited to authorized users.
001482394 520__ $$aThis book presents innovative laser desorption ionization (LDI)-active nanophotonic structures for addressing the challenges that matrix-assisted laser desorption ionization mass spectrometry (MALDI-MS) is currently facing and for enhancing LDI efficiency. It presents a variety of cutting-edge nanophotonic structures to satisfy the mass-analytical needs of sensitivity, reproducibility, and quantification. As opposed to the commercialized, conventional organic matrix used in MALDI-MS, these nanostructures are validated to be highly effective in detecting small metabolites and drugs, highlighting their considerable potential in the mass spectrometry field. It also systematically elucidates fundamental LDI processes in terms of the photo-thermal, electronic, and structural characteristics of nanophotonic structures, offering mechanistic knowledge of LDI-MS. Even though LDI-MS performance is heavily influenced by a number of nanostructure parameters, relatively little is known about the LDI processes associated with those characteristics. An in-depth understanding of nanostructure characteristics and LDI mechanisms thus paves the way for more effective, rational design and development of nanostructures with improved LDI capabilities. Further, with a focus on multiple cascades in nanostructure functions in response to laser pulse stimuli, this book provides detailed, step-by-step procedures to design and construct a nanophotonic, LDI-active platform, which may serve as a roadmap for graduate students in the field of mass spectrometry. Readers, including graduate students, researchers, and experts working in the related areas of mass spectrometry, nanophotonics, and material science and material engineering, will find a wealth of useful information in this book.
001482394 588__ $$aOnline resource; title from PDF title page (SpringerLink, viewed October 23, 2023).
001482394 650_0 $$aMatrix-assisted laser desorption-ionization.
001482394 650_0 $$aNanophotonics.
001482394 650_6 $$aDésorption-ionisation laser assistée par matrice.
001482394 650_6 $$aNanophotonique.
001482394 655_0 $$aElectronic books.
001482394 77608 $$iPrint version:$$aKim, Moon-Ju$$tLaser Desorption Ionization Mass Spectrometry Based on Nanophotonic Structure: from Material Design to Mechanistic Understanding$$dSingapore : Springer,c2023$$z9789819968770
001482394 830_0 $$aSpringer theses.
001482394 852__ $$bebk
001482394 85640 $$3Springer Nature$$uhttps://univsouthin.idm.oclc.org/login?url=https://link.springer.com/10.1007/978-981-99-6878-7$$zOnline Access$$91397441.1
001482394 909CO $$ooai:library.usi.edu:1482394$$pGLOBAL_SET
001482394 980__ $$aBIB
001482394 980__ $$aEBOOK
001482394 982__ $$aEbook
001482394 983__ $$aOnline
001482394 994__ $$a92$$bISE