001482560 000__ 04626cam\\22005417a\4500 001482560 001__ 1482560 001482560 003__ OCoLC 001482560 005__ 20231128003341.0 001482560 006__ m\\\\\o\\d\\\\\\\\ 001482560 007__ cr\un\nnnunnun 001482560 008__ 231023s2023\\\\si\a\\\\o\\\\\000\0\eng\d 001482560 019__ $$a1405405543 001482560 020__ $$a9789819946570$$q(electronic bk.) 001482560 020__ $$a9819946573$$q(electronic bk.) 001482560 020__ $$z9819946565 001482560 020__ $$z9789819946563 001482560 0247_ $$a10.1007/978-981-99-4657-0$$2doi 001482560 035__ $$aSP(OCoLC)1405413290 001482560 040__ $$aYDX$$beng$$cYDX$$dGW5XE$$dEBLCP$$dYDX$$dOCLKB$$dOCLCO$$dOCLCF 001482560 049__ $$aISEA 001482560 050_4 $$aRC271.C5$$bC94 2023 001482560 08204 $$a616.99/4061$$223/eng/20231025 001482560 24500 $$aCytokine and chemokine networks in cancer$$h[electronic resource] /$$cManzoor Ahmad Mir, editor. 001482560 260__ $$aSingapore :$$bSpringer,$$c[2023] 001482560 300__ $$a1 online resource (xvii, 440 pages) :$$billustrations 001482560 336__ $$atext$$btxt$$2rdacontent 001482560 337__ $$acomputer$$bc$$2rdamedia 001482560 338__ $$aonline resource$$bcr$$2rdacarrier 001482560 5050_ $$aChapter 1_Introduction to Cancer -- Chapter 2_Expression pattern of Chemokines in Cancer -- Chapter 3_Implications of Cytokine-Chemokine Heterogenity in Cancer -- Chapter 4_Cytokine and chemokines networks in cancer stemness -- Chapter 5_Cytokine and chemokines networks in angiogeneis -- Chapter 6_Role of Cytokine-Chemokine cascades in Epithelial to Mesenchymal Transition -- Chapter 7_Role of Chemokines in establishment of Metastatic Niche -- Chapter 8_CXCL12-CXCR4 axis in Metastasis -- Chapter 9_Chemokine and cytokine networks in the tumor microenvironment -- Chapter 10_CXCL9, CXCL10, CXCL11/CXCR3 axis and Immune Activation -- Chapter 11_CXCL8-CXCR1/2 axis in cancer and inflammatory diseases -- Chapter 12_Cytokine and Chemokine Networks in Therapeutic Resistance -- Chapter 13_Prognostic and diagnostic significance of Chemokines and cytokines in cancer -- Chapter 14_Therapeutic implications of Chemokines and cytokines networks in cancer -- Chapter 15_Chemokines in cancer therapy. 001482560 506__ $$aAccess limited to authorized users. 001482560 520__ $$aCytokine and Chemokine Networks in Cancer" provides a comprehensive exploration of the roles of cytokines and chemokines in cancer biology. It offers valuable insights into their diagnostic, prognostic, and therapeutic implications, making it a valuable resource for researchers, clinicians, and students interested in the field of cancer immunology and therapy. This book illustrates the importance and significance of the cytokine and chemokine signaling networks in tumor development and progression. It describes the complex networks mediated by cytokine and chemokine receptors promoting tumor cell proliferation, site-directed metastasis, and activation of angiogenic switch in tumor cells. The books also shed light on the heterogeneity of cytokines and chemokine in solid malignancies and their impact on tumor progression and therapeutic outcomes. The chapters provide current information about the types of cytokine-chemokine interactions in promoting cancer stem cell-like characteristics, epithelial to mesenchymal transition, and modulation of the tumor microenvironment. The significance of the complex interactions in cancer biology in the light of therapeutic resistance is also highlighted. The chapters also describe recent advancements in the therapeutic potential of targeting the pro-tumor cytokine and chemokine networks and limiting tumor cell metastasis. Finally, the book also provides a comprehensive yet representative description of a large number of challenges associated with targeting these vital chemokine-cytokine networks. Given its content, the book provides valuable information for researchers in the field of cancer biology and molecular medicine. 001482560 650_6 $$aCancer$$xChimiothérapie. 001482560 650_6 $$aCytokines$$xEmploi en thérapeutique. 001482560 650_6 $$aChimiokines$$xEmploi en thérapeutique. 001482560 650_0 $$aCancer$$xChemotherapy.$$0(DLC)sh2006006447 001482560 650_0 $$aCytokines$$xTherapeutic use. 001482560 650_0 $$aChemokines$$xTherapeutic use. 001482560 655_0 $$aElectronic books. 001482560 7001_ $$aMir, Manzoor Ahmad,$$eeditor. 001482560 77608 $$iPrint version: $$z9819946565$$z9789819946563$$w(OCoLC)1382624702 001482560 852__ $$bebk 001482560 85640 $$3Springer Nature$$uhttps://univsouthin.idm.oclc.org/login?url=https://link.springer.com/10.1007/978-981-99-4657-0$$zOnline Access$$91397441.1 001482560 909CO $$ooai:library.usi.edu:1482560$$pGLOBAL_SET 001482560 980__ $$aBIB 001482560 980__ $$aEBOOK 001482560 982__ $$aEbook 001482560 983__ $$aOnline 001482560 994__ $$a92$$bISE