Tight junctions in inflammation and cancer / Ajaz A. Bhat, Mohammad Haris, Muzafar A. Macha, Punita Dhawan, editors.
2023
QH603.C4 T54 2023
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Details
Title
Tight junctions in inflammation and cancer / Ajaz A. Bhat, Mohammad Haris, Muzafar A. Macha, Punita Dhawan, editors.
ISBN
9789819924158 (electronic bk.)
9819924154 (electronic bk.)
9819924146
9789819924141
9819924154 (electronic bk.)
9819924146
9789819924141
Published
Singapore : Springer, 2023.
Language
English
Description
1 online resource (290 pages) : illustrations (color).
Item Number
10.1007/978-981-99-2415-8 doi
Call Number
QH603.C4 T54 2023
Dewey Decimal Classification
571.6
Summary
This book provides an updated account of tight junctions of different epithelia and endothelia and addresses their anatomy, biochemistry, physiology, synthesis, assembly, and modulation. It also discusses the relationship between molecular structure, function, regulation, posttranslational modifications of tight junction proteins and their role in gut microbiota maintenance, epithelial-mesenchymal transition, and intestinal barrier dysfunction-associated disorders important for the progression of human cancers. This book presents the pathological alterations of tight junctions at the blood-brain barrier that intensify or even initiate neurological dysfunction. Further, it reviews the significance of tight junctions and tight junction proteins in cancer development, infectious diseases, allergic reactions, and autoimmune disorders. Lastly, it highlights strategies for modulating tight junctions to enhance drug availability and organ deposition. This book is immensely useful for basic, translational, clinical, and interdisciplinary cancer researchers, practicing oncologists, and immunologists.
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Access limited to authorized users.
Source of Description
Description based on print version record.
Added Author
Bhat, Ajaz A., editor.
Haris, Mohammad, editor.
Macha, Muzafar Ahmad, 1981- editor.
Dhawan, Punita, editor.
Haris, Mohammad, editor.
Macha, Muzafar Ahmad, 1981- editor.
Dhawan, Punita, editor.
Available in Other Form
TIGHT JUNCTIONS IN INFLAMMATION AND CANCER.
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Table of Contents
Chapter 1. Inflammation and Cancer: Role of Tight Junctions
Chapter 2. Regulation of tight junction by cadherin adhesion and its implication in inflammation and cancer
Chapter 3. Tight junctions, epithelial-mesenchymal transition and cancer metastasis
Chapter 4. Imaging techniques to study tight junctions
Chapter 5. Tight junction proteins as emerging drug targets: Expanding the horizons from inflammation to cancer
Chapter 6. Tight Junctions and signaling pathways in cancer
Chapter 7. Molecular architecture and function of tight junctions
Chapter 8. The role of tight junction proteins in cancer.
Chapter 2. Regulation of tight junction by cadherin adhesion and its implication in inflammation and cancer
Chapter 3. Tight junctions, epithelial-mesenchymal transition and cancer metastasis
Chapter 4. Imaging techniques to study tight junctions
Chapter 5. Tight junction proteins as emerging drug targets: Expanding the horizons from inflammation to cancer
Chapter 6. Tight Junctions and signaling pathways in cancer
Chapter 7. Molecular architecture and function of tight junctions
Chapter 8. The role of tight junction proteins in cancer.