Mechanisms and emerging therapies in tremor disorders / Giuliana Grimaldi, Mario Manto, editors.

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Mechanisms and emerging therapies in tremor disorders / Giuliana Grimaldi, Mario Manto, editors.

Second edition.

9783031261282 (electronic bk.)
3031261283 (electronic bk.)
9783031261275
3031261275

Cham, Switzerland : Springer, [2023]

English

1 online resource (x, 558 pages) : illustrations (black and white, and colour).

10.1007/978-3-031-26128-2 doi

RC376.5 .M43 2023

616.8

Tremor is intimately linked to the numerous interactions of the central and peripheral nervous system components tuning motor control, from the cerebral cortex to the peripheral effectors. Activities of central generators, reflex loop delays, inertia, stiffness, and damping are all factors that influence the features of tremor. This completely updated new edition discusses the pathophysiology of tremor, including membrane mechanisms and rodent models, the advances in genetics, and the musculoskeletal models pertinent to body oscillations. The main forms of tremor encountered during clinical practice are considered, taking into account neuroimaging aspects. The book covers recent advances in methodologies and techniques of assessment and provides practical information for daily management. This new edition is informed by the guidelines of the Tremor Task Force of the International Parkinson and Movement Disorders Society. New chapters include Classification of Tremors, Medically Induced Tremors, Resting State fMRI, and Gabaergic Pathways. In addition to pharmacological treatments, neurosurgical approaches such as deep brain stimulation (DBS) and thalamotomy are discussed. Emerging techniques under development are also introduced.

Includes index.

Access limited to authorized users.

Description based on print version record.

Contemporary clinical neuroscience.

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