Surgical research in implant dentistry / Michel M. Dard, editor.
Dard, Michel M., editor.
2023
RK667.I45 S87 2023
Available Online

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Title Surgical research in implant dentistry / Michel M. Dard, editor.
ISBN 9783031372346 electronic book
3031372344 electronic book
3031372336
9783031372339
DOI https://doi.org/10.1007/978-3-031-37234-6
Published Cham : Springer, 2023.
Language English
Description 1 online resource (450 p.)
Item Number 10.1007/978-3-031-37234-6 doi
Call Number RK667.I45 S87 2023
Dewey Decimal Classification 617.6/93
Summary This book explores, in a comprehensive and systematic manner, Surgical Research methodologies to the design and development of investigational studies in the field of implant-based oral rehabilitation. Such studies are linked in a chain binding in vitro, in vivo, ex vivo, and digital evaluations. An ambitious objective consists in exposing how investigators can generate and deliver knowledge by capturing synergy coming from preclinical and clinical trials. Accordingly, throughout the book, translational aspects are closely scrutinized. The opening chapters consider materials, methods and procedures for preclinical and clinical studies in which approaches and models are extensively described. The focus then moves to the process by which application of histology, biomechanics, biomarkers, cellular/molecular biology, and imaging technologies lead to new results and consequently novel treatment concepts in implant dentistry, implant borne prosthetic rehabilitations and the replacement or regeneration of tissues. Finally, the exciting opportunities afforded by the digital world are addressed. This book shall be a valuable resource and time-saving tool for a wide audience of researchers, students, practitioners, and academics.
Note 3.2.1.4 Function and Physiology (Movement, Loading)
Access Note Access limited to authorized users.
Source of Description Description based on online resource; title from digital title page (viewed on November 06, 2023).
Added Author Dard, Michel M., editor.
Available in Other Form Surgical Research in Implant Dentistry
Linked Resources Online Access
Record Appears in Online Resources > Ebooks
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Intro
Foreword
Contents
1: The Method Sets the Tone
1.1 Introduction
1.2 The Heroes
1.3 The Endless Revolution
1.3.1 The Hypothesis
1.3.2 The Design
1.3.3 Evidence-Based Dentistry
1.4 Conclusion
References
Evidence-Based Dentistry Related References
2: Preclinical Studies Design and Place of Rodents
2.1 Experimental Animal Model
2.1.1 Animal Species: Naturally-Occurring, Purpose-Bread, and/or Genetically Modified
2.1.2 General Use in Medical Devices Research
2.1.3 Financial Considerations
2.2 Surgical Model

2.2.1 Surgical Anatomical Site and Surgical Procedures for Implant Dentistry
2.2.1.1 Surgical Locations
Extraoral
Anatomy and Histology
Function and Physiology (Movement, Loading)
Advantages/Inconveniences in Implant Dentistry
Recommendations
Intraoral
Anatomy and Histology
Function and Physiology (Movement, Loading, and Occlusion)
Advantages/Inconveniences in Implant Dentistry Anatomy and Histology
Recommendations
2.2.1.2 Surgical Procedures
Extraoral: Description of the Procedures

Animal Welfare, Preparation for Survival Surgery, and Anesthesia (General, Local)
Surgical Step by Step: Anterior-Distal Surface of Femur Metaphysis
Surgical Step-by-Step:Femoral Condyle
Surgical Step by Step: Medial-Proximal Surface of Tibia Metaphysis
Follow-up and Termination
Recommendations
Intraoral: Description of the Procedures
Animal Welfare, Preparation for Survival Surgery and Anesthesia (General, Local)
Surgical Step-by-Step: Rat
Surgical Step-by-Step: Mouse
Follow-Up and Termination
Recommendations
2.3 Investigative Methods of Evaluation

2.3.1 X-Rays
2.3.2 Micro-CT
2.3.3 Histology (Remove Implant or Not)
2.3.4 Optics and Electronic Histology-Histomorphometry (Including Immunohistolabeling)
2.3.5 Biomechanics
2.3.5.1 Push-in Test
2.3.5.2 Pull-Out Test
2.3.6 Bacteriology
2.3.7 Genomics
2.4 Flag Ship Results from the Literature Using These Experimental-Surgical Models (Outlining Your Own Results): Critical Mini-Review
2.5 Expert Opinion: Balancing Models (Experimental and Surgical) Validation and Validity
References
3: Preclinical Studies Design and Place of Rabbits

3.1 Experimental Animal Model
3.1.1 Animal Species: Naturally-Occurring, Purpose-Bred and/or Genetically Modified
3.1.1.1 Animal Welfare
3.1.1.2 Handling and Husbandry
3.1.1.3 Health Status
3.1.2 General Use in Medical Devices Research
3.1.3 Financial Considerations
3.2 Surgical Model: Surgical Anatomical Site and Surgical Procedures for Implant Dentistry
3.2.1 Surgical Locations, Anatomy, and Histology
3.2.1.1 General Anatomical Information
3.2.1.2 Extraoral
Femur and Tibia
Skull
3.2.1.3 Intra Oral
Maxilla and Mandible
Sinuses

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