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001482688 0247_ $$a10.1007/978-981-99-6564-9$$2doi
001482688 035__ $$aSP(OCoLC)1406410312
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001482688 050_4 $$aRS199.5$$b.A38 2023
001482688 08204 $$a615/.6$$223/eng/20231102
001482688 24500 $$aAdvanced drug delivery :$$bmethods and applications /$$cTuhin Subhra Santra, Ashwini Uma Surendra Shinde, editors.
001482688 260__ $$aSingapore :$$bSpringer,$$c2023.
001482688 300__ $$a1 online resource (368 p.).
001482688 4901_ $$aStudies in mechanobiology, tissue engineering and biomaterials ;$$vv.26
001482688 500__ $$aThermoporation Based Drug Delivery Systems
001482688 5050_ $$aIntro -- Preface -- Contents -- Biological Methods for Drug Delivery -- 1 Introduction -- 2 Biological Barriers to Drug Delivery -- 3 Biological Methods for Drug Delivery -- 3.1 Endogenous Cell Membranes Vectors -- 3.2 Exogenous Substances: Viruses, VLPs and Virosomes -- 3.3 Extracellular Vesicles -- 4 BNPs Production Methods -- 4.1 Synthesis of Cell Membrane-Based BNPs -- 4.2 Synthesis of Exogenous Substances (Viruses, VLPs and Virosomes) Based BNPs -- 4.3 Synthesis of Extracellular Vesicles-Based BNPs -- 5 Clinical Trials of Biomimetic Nanoparticles -- 6 Challenges and Future Directions
001482688 5058_ $$a7 Conclusion -- References -- Liposome-Based Drug Delivery-A New Therapeutic Paradigm -- 1 Introduction -- 2 Synthesis Techniques -- 2.1 Physical Methods -- 2.2 Chemical Methods -- 2.3 Characterization of Synthesized Liposomes -- 3 Infectious Diseases -- 3.1 Overview of Liposomal Drug Delivery for Infectious Diseases -- 3.2 Recent Technologies and Advances with Liposomal Drug Delivery -- 4 Mycobacterial Infections -- 4.1 Overview of Mycobacterial Infections -- 4.2 Clinical Studies on Liposomal Drug Delivery for Mycobacterial Infectious -- 5 Anticancer Drug Delivery
001482688 5058_ $$a5.1 Overview of Anticancer Drug Delivery -- 5.2 Examples of Anticancer Drugs Used in Targeted Liposomal Drug Delivery -- 5.3 Challenges of Liposomal Delivery of Anticancer Drugs -- 5.4 Future Directions of Research on Liposomal Targeted Drug Delivery of Anticancer Drugs -- 6 Lung Specific Drug Delivery -- 7 Future Prospects -- 8 Conclusion -- References -- Multifunctional Liposomes to Attain Targeting, Stimuli Sensitive Drug Release and Imaging Cancer -- 1 Introduction -- 2 Structure of Liposomes -- 3 Liposomes in Cancer -- 4 Methods for the Preparation of Liposomes
001482688 5058_ $$a4.1 Thin Film Hydration Process -- 4.2 Solvent Injection Process -- 4.3 Reverse Phase Evaporation Method -- 4.4 Detergent Removal Method -- 4.5 Size Reduction Method -- 5 Marketed Liposomal Formulation -- 6 Dual or Multi Drug Loaded Liposomes -- 7 Prolongation of Systemic Circulation of Liposomes -- 8 Strategies for Targeting Liposomes -- 9 Stimuli Sensitive Drug Delivery by Liposomes -- 10 Imaging of Cancer Using Liposomes -- 11 Cell Penetrating Liposomes -- 12 Multifunctional Liposomes -- 13 Clinical Trials Using Liposomal Formulations -- 14 Applications of Liposomes in Healthcare
001482688 5058_ $$a15 Conclusion -- References -- Electroporation-Based Drug Delivery -- 1 Introduction -- 2 Mechanisms -- 3 Bulk Electroporation (BEP) -- 4 Single-Cell Electroporation (SCEP) -- 5 Localized Single-Cell Electroporation (LSCEP) -- 6 Clinical Trials -- 7 Pros and Cons of Electroporation -- 8 Concluding Remarks and Future Aspect -- References -- Mechanoporation-Based Drug Delivery -- 1 Introduction -- 2 Basic Mechanism -- 3 Different Methods of Mechanoporation -- 4 Device Fabrication -- 5 Advantages of Mechanoporation -- 6 Drawbacks of Mechanoporation -- 7 Conclusions -- References
001482688 506__ $$aAccess limited to authorized users.
001482688 520__ $$aThis book provides an overview of various drug delivery systems at the cellular level including biological, chemical methods, and most importantly physical methods such as photoporation, electroporation, mechanoporation, and device-based techniques (e.g., microfluidics), as well as organism-level techniques including nanomaterials, biomaterials, and transdermal. Drug delivery (DD) can be defined as the method and route by which an active pharmaceutical ingredient (API) is administered to promote its desired pharmacological effect and/or convenience and/or to reduce adverse effects. Drug delivery systems are developed to maximize drug efficacy and minimize side effects. As drug delivery technologies improve, the drug becomes safer and more comfortable for patients to use. During the last seven decades, extraordinary progress has been made in drug delivery technologies, such as systems for long-term delivery for months and years, localized delivery, and targeted delivery. The advances, however, will face the next phase considering the future technologies that we need to overcome many physicochemical barriers for new formulation development and biological unknowns for treating various diseases. Thus, various technologies are built at a single-cell level as well as an organism level. This book is useful at the university level for graduate courses or research studies and biotechnology-based companies with research and development on cell-based analysis, diagnosis, or drug screening. This book is also very useful for researchers in drug delivery technologies, which came in frontier research for the past decade.
001482688 588__ $$aOnline resource; title from PDF title page (SpringerLink, viewed November 2, 2023).
001482688 650_0 $$aDrug delivery systems$$xTechnological innovations.
001482688 650_6 $$aSystèmes d'administration de médicaments$$xInnovations.
001482688 655_0 $$aElectronic books.
001482688 7001_ $$aSantra, Tuhin Subhra.
001482688 7001_ $$aShinde, Ashwini Uma Surendra.
001482688 77608 $$iPrint version:$$aSantra, Tuhin Subhra$$tAdvanced Drug Delivery$$dSingapore : Springer,c2023$$z9789819965632
001482688 830_0 $$aStudies in mechanobiology, tissue engineering, and biomaterials ;$$v26.
001482688 852__ $$bebk
001482688 85640 $$3Springer Nature$$uhttps://univsouthin.idm.oclc.org/login?url=https://link.springer.com/10.1007/978-981-99-6564-9$$zOnline Access$$91397441.1
001482688 909CO $$ooai:library.usi.edu:1482688$$pGLOBAL_SET
001482688 980__ $$aBIB
001482688 980__ $$aEBOOK
001482688 982__ $$aEbook
001482688 983__ $$aOnline
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