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001482690 001__ 1482690
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001482690 019__ $$a1406408472
001482690 020__ $$a9789819965076$$q(electronic bk.)
001482690 020__ $$a9819965071$$q(electronic bk.)
001482690 020__ $$z9789819965069
001482690 020__ $$z9819965063
001482690 0247_ $$a10.1007/978-981-99-6507-6$$2doi
001482690 035__ $$aSP(OCoLC)1406410374
001482690 040__ $$aEBLCP$$beng$$cEBLCP$$dGW5XE$$dYDX$$dEBLCP$$dOCLCO
001482690 049__ $$aISEA
001482690 050_4 $$aRS201.N35$$bS38 2023
001482690 08204 $$a615/.6$$223/eng/20231103
001482690 1001_ $$aSavari, Mohammad-Nabil.
001482690 24510 $$aTheranostic iron-oxide based nanoplatforms in oncology :$$bsynthesis, metabolism, and toxicity for simultaneous imaging and therapy /$$cMohammad-Nabil Savari, Ali Jabali.
001482690 260__ $$aSingapore :$$bSpringer,$$c2023.
001482690 300__ $$a1 online resource (416 p.).
001482690 4901_ $$aNanomedicine and Nanotoxicology
001482690 500__ $$a7.2.2 Nanoplatforms That Deliver in Response to Exogenous Stimuli
001482690 504__ $$aIncludes bibliographical references.
001482690 5050_ $$aIntro -- Preface -- Acknowledgments -- Contents -- 1 Introduction -- References -- 2 Drug Conjugation Chemistry in Iron Oxide Nanoparticles (IONPs) -- 2.1 Covalent Drug-Conjugated Iron Oxide Nanoparticles -- 2.1.1 Amide Linkage Drug Conjugation -- 2.1.2 Drug Conjugation with pH-Sensitive Bonding -- 2.1.3 Drug Conjugation with Enzymatically Responsive Bonding -- 2.1.4 Oxidation/Reduction Drug Conjugation -- 2.2 Non-Covalent Drug-Conjugated Iron Oxide Nanoparticles (IONPs) -- 2.2.1 Hydrophobic Drug Conjugation -- 2.2.2 Drug Conjugation Using Electrostatics
001482690 5058_ $$a2.2.3 Drug Conjugation with Encapsulation -- References -- 3 Superparamagnetic Iron Oxide Nanoparticle (SPION) Synthesis -- 3.1 Physical Methods -- 3.1.1 Deposition in the Gas Phase -- 3.1.2 Lithography Using Electronic Beam -- 3.1.3 Laser Ablation with Pulses -- 3.1.4 Pyrolysis Caused by a Laser -- 3.1.5 Strong Ball Milling -- 3.1.6 Combustion -- 3.2 Chemical Methods -- 3.2.1 Chemical Coprecipitation Synthesis -- 3.2.2 Thermolysis (Thermal Decomposition) -- 3.2.3 Microemulsions -- 3.2.4 Synthesis Using Hydrothermal Method -- 3.3 Biological Approach -- References
001482690 5058_ $$a4 Properties of Iron Oxide Nanoparticles (IONPs) -- 4.1 Structural Properties -- 4.1.1 Colloidal Stability -- 4.1.2 Shape and Size -- 4.1.3 Charge of Surface -- 4.2 Magnetic Properties -- 4.3 Thermal Properties -- 4.4 Optical Properties -- 4.4.1 Fluorescence Techniques and Encapsulated IONPs -- References -- 5 Pharmacokinetics of IONPs -- 5.1 Absorption/Uptake -- 5.1.1 Size and Coating Material's Impact on Absorption -- 5.1.2 Charge's Impact on Uptake and Absorption -- 5.1.3 Uptake of IONPs in the Brain -- 5.2 Distribution
001482690 5058_ $$a5.2.1 Iron and IONP Physicochemical Properties Affecting the Distribution -- 5.3 Metabolism -- 5.4 Affecting the Cell Physiology -- 5.4.1 Influence on Cell Proliferation -- 5.4.2 Effect on Stem Cell Differentiation -- 5.4.3 Affects Cell Migration -- 5.5 Excretion -- 5.6 Regulation of Iron in Human -- 5.6.1 Human Body's Iron Flow -- 5.6.2 The Liver Is the Main Organ for Iron Homeostasis -- 5.6.3 Iron Regulation -- 5.6.4 Macrophages Are in Charge of Iron Homeostasis -- 5.6.5 Monocytes and the Iron Metabolism Process -- 5.6.6 Iron-Related Infection and Immunity -- References
001482690 5058_ $$a6 Magnetic Nanoparticles in Stimuli-Responsive Drug Delivery Systems -- 6.1 Drug Delivery Systems with Stimuli-Responsiveness Through Ligand-Mediated MNPs -- 6.1.1 Organic Ligands -- 6.1.2 Inorganic Ligands -- 6.1.3 Hybrid Inorganic-Organic Ligands -- 6.2 The Most Common Methods for Synthesizing MNP-Based Drug Delivery Systems -- 6.2.1 Thin Films Hydration -- 6.2.2 Evaporation Emulsion -- 6.2.3 Solvent Exchange -- References -- 7 IONPs-Based Treatment Methods -- 7.1 Chemotherapy -- 7.2 Stimuli-Responsive Delivery Nanoplatforms -- 7.2.1 Endogenous Stimuli-Responsive Nanoplatforms
001482690 506__ $$aAccess limited to authorized users.
001482690 520__ $$aThis book highlights the most efficient and latest ways to deal with cancer, focusing on IONPs. The book describes some well-designed surface modifications performed through several functional materials over the surface of IONPs, which results in the development of multifunctional IONPs-based delivery nanoplatforms by enhancing solubility, stability, and avoiding side effects on healthy cells. Several types of stimuli-responsive IONPs-based strategies are also discussed. Owing to magnetic, structural, and thermal properties, IONPs themselves can be utilized for magnetic targeting, magnetic hyperthermia, and phototherapy. Significant advancements are presented in IONPs-based immunotherapy, radiotherapy, and sonodynamic therapy for the efficient treatment of cancer. Finally, the book presents RIONs which serve as the parent platform for the development of powerful DMCAs utilized in SPECT/MRI and PET/MRI applications.
001482690 588__ $$aOnline resource; title from PDF title page (SpringerLink, viewed November 3, 2023).
001482690 650_6 $$aNanoparticules.
001482690 650_6 $$aSystèmes d'administration de médicaments$$xInnovations.
001482690 650_0 $$aNanoparticles.$$0(DLC)sh 85089689
001482690 650_0 $$aCancer$$xTreatment$$xTechnological innovations.$$0(DLC)sh2006006447
001482690 650_0 $$aDrug delivery systems$$xTechnological innovations.
001482690 655_0 $$aElectronic books.
001482690 7001_ $$aJabali, Ali.
001482690 77608 $$iPrint version:$$aSavari, Mohammad-Nabil$$tTheranostic Iron-Oxide Based Nanoplatforms in Oncology$$dSingapore : Springer,c2023$$z9789819965069
001482690 830_0 $$aNanomedicine and nanotoxicology.
001482690 852__ $$bebk
001482690 85640 $$3Springer Nature$$uhttps://univsouthin.idm.oclc.org/login?url=https://link.springer.com/10.1007/978-981-99-6507-6$$zOnline Access$$91397441.1
001482690 909CO $$ooai:library.usi.edu:1482690$$pGLOBAL_SET
001482690 980__ $$aBIB
001482690 980__ $$aEBOOK
001482690 982__ $$aEbook
001482690 983__ $$aOnline
001482690 994__ $$a92$$bISE