Ferroptosis in health and disease / Daolin Tang, editor.
Tang, Daolin, editor.
2023
QH671 .F47 2023
Available Online

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Title
Ferroptosis in health and disease / Daolin Tang, editor.
Edition
Second edition.
ISBN
9783031391712 electronic book
3031391713 electronic book
9783031391705
3031391705
DOI
https://doi.org/10.1007/978-3-031-39171-2
Published
Cham, Switzerland : Springer, [2023]
Language
English
Description
1 online resource (490 pages) : color illustrations.
Item Number
10.1007/978-3-031-39171-2 doi
Call Number
QH671 .F47 2023
Dewey Decimal Classification
571.9/36
Summary
This updated and expanded volume gives new insights on ferroptosis an iron-dependent form of non-apoptotic cell death. The collection of chapters discusses the two major pathways through which ferroptosis can occur: the extrinsic or transporter-dependent pathway and the intrinsic or enzyme-regulated pathway. Readers will gain an understanding of the multiple levels, on which this special cell death is regulated. Hence, the contributions will take a closer look at epigenetic, transcriptional, posttranscriptional and posttranslational layers. Among the described regulators and transcription factors are GPX4, ACSL4 and NFE2L2. This edited volume collects reviews related to current knowledge on the integrated molecular machinery of ferroptosis, thereby also describing how dysregulated ferroptosis is involved in human diseases.
Bibliography, etc. Note
Includes bibliographical references.
Access Note
Access limited to authorized users.
Source of Description
Description based on online resource; title from digital title page (viewed on November 10, 2023).
Added Author
Tang, Daolin, editor.
Available in Other Form
Ferroptosis in health and disease.
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Chapter 1. Lipid Metabolism and Homeostasis in Ferroptosis
Chapter 2. Iron Metabolism and Ferroptosis
Chapter 3. Targeting Epigenetic Regulation of Ferroptosis in Cancer Therapy
Chapter 4. The Role of Autophagy in Ferroptosis
Chapter 5. Heat Shock Proteins and HSF1 in Ferroptosis
Chapter 6. The Ongoing Search for a Biomarker of Ferroptosis
Chapter 7. p53 and Ferroptosis
Chapter 8. Ferroptosis in Cardiovascular Disease
Chapter 9. Understanding Ferroptosis from a Free Radical Perspective
Chapter 10. The NRF2-anti-ferroptosis Axis in Health and Disease
Chapter 11. Epigenetic Modification in Ferroptosis
Chapter 12. Organelle-specific Mechanisms of Ferroptosis
Chapter 13. Ferroptosis: A Promising Therapeutic Target for Cardiovascular Diseases
Chapter 14. Ferroptosis in Central Nervous System HypoxiaIschemia
Chapter 15. Involvement of Ferroptosis in Lupus Nephritis
Chapter 16. Ferroptosis and Infectious Diseases
Chapter 17. Selenium Metabolic Pathway in Ferroptotic Cell Death
Chapter 18. Epigenetic and Post-Translational Regulation of Ferroptosis
Chapter 19. Phospholipid Peroxidation in Health and Disease
Chapter 20
PKCIIACSL4 Axis Triggers Ferroptosis and Its Potential Implication in Ferroptosis-Related Diseases
Chapter 21. Cancer Treatment with Ferroptosis by a Combination of Iron Nanoparticles and Gene Therapy
Chapter 22. Inhibitors of Oxytosis/Ferroptosis: A New Class of Therapeutics for Alzheimers Disease.

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