001482889 000__ 04286cam\\2200529\i\4500 001482889 001__ 1482889 001482889 003__ OCoLC 001482889 005__ 20231128003355.0 001482889 006__ m\\\\\o\\d\\\\\\\\ 001482889 007__ cr\cn\nnnunnun 001482889 008__ 231107s2023\\\\sz\a\\\\ob\\\\000\0\eng\d 001482889 019__ $$a1406831108$$a1407313440 001482889 020__ $$a9783031391712$$qelectronic book 001482889 020__ $$a3031391713$$qelectronic book 001482889 020__ $$z9783031391705 001482889 020__ $$z3031391705 001482889 0247_ $$a10.1007/978-3-031-39171-2$$2doi 001482889 035__ $$aSP(OCoLC)1407508983 001482889 040__ $$aGW5XE$$beng$$erda$$epn$$cGW5XE$$dEBLCP$$dYDX$$dOCLCO 001482889 049__ $$aISEA 001482889 050_4 $$aQH671$$b.F47 2023 001482889 08204 $$a571.9/36$$223/eng/20231107 001482889 24500 $$aFerroptosis in health and disease /$$cDaolin Tang, editor. 001482889 250__ $$aSecond edition. 001482889 264_1 $$aCham, Switzerland :$$bSpringer,$$c[2023] 001482889 300__ $$a1 online resource (490 pages) :$$bcolor illustrations. 001482889 336__ $$atext$$btxt$$2rdacontent 001482889 337__ $$acomputer$$bc$$2rdamedia 001482889 338__ $$aonline resource$$bcr$$2rdacarrier 001482889 504__ $$aIncludes bibliographical references. 001482889 5050_ $$aChapter 1. Lipid Metabolism and Homeostasis in Ferroptosis -- Chapter 2. Iron Metabolism and Ferroptosis -- Chapter 3. Targeting Epigenetic Regulation of Ferroptosis in Cancer Therapy -- Chapter 4. The Role of Autophagy in Ferroptosis -- Chapter 5. Heat Shock Proteins and HSF1 in Ferroptosis -- Chapter 6. The Ongoing Search for a Biomarker of Ferroptosis -- Chapter 7. p53 and Ferroptosis -- Chapter 8. Ferroptosis in Cardiovascular Disease -- Chapter 9. Understanding Ferroptosis from a Free Radical Perspective -- Chapter 10. The NRF2-anti-ferroptosis Axis in Health and Disease -- Chapter 11. Epigenetic Modification in Ferroptosis -- Chapter 12. Organelle-specific Mechanisms of Ferroptosis -- Chapter 13. Ferroptosis: A Promising Therapeutic Target for Cardiovascular Diseases -- Chapter 14. Ferroptosis in Central Nervous System HypoxiaIschemia -- Chapter 15. Involvement of Ferroptosis in Lupus Nephritis -- Chapter 16. Ferroptosis and Infectious Diseases -- Chapter 17. Selenium Metabolic Pathway in Ferroptotic Cell Death -- Chapter 18. Epigenetic and Post-Translational Regulation of Ferroptosis -- Chapter 19. Phospholipid Peroxidation in Health and Disease -- Chapter 20 -- PKCIIACSL4 Axis Triggers Ferroptosis and Its Potential Implication in Ferroptosis-Related Diseases -- Chapter 21. Cancer Treatment with Ferroptosis by a Combination of Iron Nanoparticles and Gene Therapy -- Chapter 22. Inhibitors of Oxytosis/Ferroptosis: A New Class of Therapeutics for Alzheimers Disease. 001482889 506__ $$aAccess limited to authorized users. 001482889 520__ $$aThis updated and expanded volume gives new insights on ferroptosis an iron-dependent form of non-apoptotic cell death. The collection of chapters discusses the two major pathways through which ferroptosis can occur: the extrinsic or transporter-dependent pathway and the intrinsic or enzyme-regulated pathway. Readers will gain an understanding of the multiple levels, on which this special cell death is regulated. Hence, the contributions will take a closer look at epigenetic, transcriptional, posttranscriptional and posttranslational layers. Among the described regulators and transcription factors are GPX4, ACSL4 and NFE2L2. This edited volume collects reviews related to current knowledge on the integrated molecular machinery of ferroptosis, thereby also describing how dysregulated ferroptosis is involved in human diseases. 001482889 588__ $$aDescription based on online resource; title from digital title page (viewed on November 10, 2023). 001482889 650_0 $$aCell death. 001482889 650_6 $$aCellules$$xMort. 001482889 655_0 $$aElectronic books. 001482889 7001_ $$aTang, Daolin,$$eeditor. 001482889 77608 $$iPrint version:$$tFerroptosis in health and disease.$$bSecond edition.$$dCham : Springer, 2023$$z9783031391705$$w(OCoLC)1400094484 001482889 852__ $$bebk 001482889 85640 $$3Springer Nature$$uhttps://univsouthin.idm.oclc.org/login?url=https://link.springer.com/10.1007/978-3-031-39171-2$$zOnline Access$$91397441.1 001482889 909CO $$ooai:library.usi.edu:1482889$$pGLOBAL_SET 001482889 980__ $$aBIB 001482889 980__ $$aEBOOK 001482889 982__ $$aEbook 001482889 983__ $$aOnline 001482889 994__ $$a92$$bISE