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Table of Contents
Cover
Contents
Acknowledgments
Abbreviations
Introduction
1. Ethics and Economics of Longevity: Is It Right to Study Aging?
2. Why Do We Age?
3. Studying the Genetics of Human Longevity: Centenarians and What We Can Learn from Them
4. Long-Lived Species and Longevity Mutants of Model Organisms
5. What Is Aging (and How Can We Measure It)? Biomarkers of Aging and "Quality of Life" Metrics
6. Insulin Signaling, FOXO Targets, and the Regulation of Longevity and Reproduction
7. Dietary Restriction: Nutrient and Genetic Regulation of Longevity and Reproduction
8. Taking out the Trash: Molecular Homeostasis in the Regulation of Longevity
9. Powering Longevity: Mitochondria's Role in Aging and Longevity
10. Dracula and Wolverine: How DNA Repair and Cell Replacement Can Help Us Live Long
11. Use It or Lose It: Reproductive Aging, the Germline, and Longevity
12. Sex, Flies (and Worms), and Videotape: The Battle of the Sexes
13. I See Dead Flies: Neurons and Sensory Regulation of Longevity
14. Don't You Forget about Me: What We Are Learning about Cognitive Aging and How to Slow It
15. Lamarck's Revenge? Transgenerational Inheritance, the "Molecular Clock," and the Epigenetic Regulation of Longevity
16. Gut Feelings: The Microbiome and Aging
17. Long Life in a Pill? The Future of Longevity: From Bench to Biotech
Notes
Index
A Note on the Type
Contents
Acknowledgments
Abbreviations
Introduction
1. Ethics and Economics of Longevity: Is It Right to Study Aging?
2. Why Do We Age?
3. Studying the Genetics of Human Longevity: Centenarians and What We Can Learn from Them
4. Long-Lived Species and Longevity Mutants of Model Organisms
5. What Is Aging (and How Can We Measure It)? Biomarkers of Aging and "Quality of Life" Metrics
6. Insulin Signaling, FOXO Targets, and the Regulation of Longevity and Reproduction
7. Dietary Restriction: Nutrient and Genetic Regulation of Longevity and Reproduction
8. Taking out the Trash: Molecular Homeostasis in the Regulation of Longevity
9. Powering Longevity: Mitochondria's Role in Aging and Longevity
10. Dracula and Wolverine: How DNA Repair and Cell Replacement Can Help Us Live Long
11. Use It or Lose It: Reproductive Aging, the Germline, and Longevity
12. Sex, Flies (and Worms), and Videotape: The Battle of the Sexes
13. I See Dead Flies: Neurons and Sensory Regulation of Longevity
14. Don't You Forget about Me: What We Are Learning about Cognitive Aging and How to Slow It
15. Lamarck's Revenge? Transgenerational Inheritance, the "Molecular Clock," and the Epigenetic Regulation of Longevity
16. Gut Feelings: The Microbiome and Aging
17. Long Life in a Pill? The Future of Longevity: From Bench to Biotech
Notes
Index
A Note on the Type