001484118 000__ 04585cam\\22005297i\4500 001484118 001__ 1484118 001484118 003__ OCoLC 001484118 005__ 20240117003314.0 001484118 006__ m\\\\\o\\d\\\\\\\\ 001484118 007__ cr\cn\nnnunnun 001484118 008__ 231117s2023\\\\sz\a\\\\o\\\\\000\0\eng\d 001484118 019__ $$a1407843171$$a1408377790$$a1409030918 001484118 020__ $$a9783031363900$$q(electronic bk.) 001484118 020__ $$a3031363906$$q(electronic bk.) 001484118 020__ $$z3031363892 001484118 020__ $$z9783031363894 001484118 0247_ $$a10.1007/978-3-031-36390-0$$2doi 001484118 035__ $$aSP(OCoLC)1409572061 001484118 040__ $$aGW5XE$$beng$$erda$$epn$$cGW5XE$$dEBLCP$$dYDX$$dOCLKB$$dOCLCQ$$dOCLCO$$dYDX$$dOCLCO 001484118 049__ $$aISEA 001484118 050_4 $$aQP623$$b.R537 2023 001484118 08204 $$a572.8/8$$223/eng/20231117 001484118 24500 $$aRNA structure and function /$$cJan Barciszewski, editor. 001484118 264_1 $$aCham, Switzerland :$$bSpringer,$$c2023. 001484118 300__ $$a1 online resource (764 pages) :$$billustrations (black and white, and color). 001484118 336__ $$atext$$btxt$$2rdacontent 001484118 337__ $$acomputer$$bc$$2rdamedia 001484118 338__ $$aonline resource$$bcr$$2rdacarrier 001484118 4901_ $$aRNA technologies ;$$vvolume 14 001484118 5050_ $$a1. Computational Tools for Functional Analysis of Circular RNAs -- 2. The Hidden Layer of RNA Variants -- 3. Functional Role of Non-Coding RNAs in Prostate Cancer: From Biomarker to Therapeutic Targets -- 4. The structure, function, and modification of non-coding RNAs in cardiovascular system,- 5. Contribution of RNA Species in Sexually Transmitted Infections -- 6. Hypoxia and Epithelial-to-Mesenchymal Transition (EMT) in Cancer: A Non-Coding RNA Perspective -- 6. A Study on the Role of piRNAs in Cancer Epigenetics -- 7. Modified Nucleosides as RNA Components. Structure, Biological Role and Drug Design -- 8. Multifaceted Functions of RNA m6A Modification in Modulating Regulated Cell Death -- 9. Incorporation of Pseudouridine into RNA for Biochemical and Biophysical Studies -- 10. Molecular Dynamics Simulations of Chemically Modified Ribonucleotides. 001484118 506__ $$aAccess limited to authorized users. 001484118 520__ $$aThis book focuses on the current status of our understanding of RNA, a key biological molecule. The various RNAs covered are messenger RNA, ribosomal RNA, transfer RNA, noncoding RNAs, modified nucleosides, and RNA enzymes. The different chapters detail methods to investigate RNA structure and function, the chemistry of modified RNAs, and the latest advances in our understanding of the vast array of biological processes in which RNA is involved. RNA, in one form or another, touches almost everything in a cell. RNA has both structural and catalytic properties. RNA fulfills a broad range of functions. These molecules are no longer seen as passive elements transferring the genetic information from DNA into proteins but regulate the activity of genes during development, cellular differentiation, and changing environments. RNAs are involved in various aspects of cell physiology and disease development. Discoveries of RNA with unexpected diverse functions in healthy and diseased cells, such as the role of RNA as both the source and countermeasure to cancer or severe viral infection, stimulate new trends, passion, and solutions for molecular medicine. In this book, fundamental questions about the biochemical and genetic importance of RNA, how mRNAs are generated and used to produce proteins, how noncoding and catalytic RNAs mediate key cellular processes, how to determine RNA structure and how to apply RNA in treatment of diseases. This book is an essential resource for researches in academia and industry contributing to the development of new RNA therapeutics. The book is geared toward scientists from the graduate level on up and particularly appeals to active investigators in RNA biology, molecular biology, and biochemistry. 001484118 588__ $$aDescription based on print version record. 001484118 650_6 $$aARN. 001484118 650_0 $$aRNA.$$0(DLC)sh 85093159 001484118 655_0 $$aElectronic books. 001484118 7001_ $$aBarciszewski, Jan,$$eeditor. 001484118 77608 $$iPrint version:$$tRNA STRUCTURE AND FUNCTION.$$d[Place of publication not identified] : SPRINGER INTERNATIONAL PU, 2023$$z3031363892$$w(OCoLC)1381191332 001484118 830_0 $$aRNA technologies ;$$vv. 14. 001484118 852__ $$bebk 001484118 85640 $$3Springer Nature$$uhttps://univsouthin.idm.oclc.org/login?url=https://link.springer.com/10.1007/978-3-031-36390-0$$zOnline Access$$91397441.1 001484118 909CO $$ooai:library.usi.edu:1484118$$pGLOBAL_SET 001484118 980__ $$aBIB 001484118 980__ $$aEBOOK 001484118 982__ $$aEbook 001484118 983__ $$aOnline 001484118 994__ $$a92$$bISE