@article{1484236,
      recid = {1484236},
      author = {Shahi, Mehdi Hayat,},
      title = {Role of signaling pathways in brain tumoriogenesis /},
      pages = {1 online resource},
      abstract = {This book provides acomprehensive overview of cell  signalling pathways and morphogens in the genesis of brain  tumours. It also explains the role of brain tumour stem  cells in the brain tumour progression. It also elucidates  the novel early biomarkers that can be utilized to diagnose  brain tumours. It presents the basic developmental pathways  and morphogens, including retinoic acid and TGF-b that  promote brain tumorigenesis. The chapters illustrate the  role of stem cells and stem cells mediated cell signalling  pathways including, Sonic hedgehog, Notch, Wnt in the brain  tumour growth. The chapters also emphasize the role of  transcription factors, mainlyNanog, Sox, BMI1, HIF1 and  Pax6 in the brain tumouriogensis. It highlights the role of  NF-kb, Myc and neurotrophins in the brain tumour  development. Finally, the book summarizes the potential  early therapeutic targets and targeted drug discovery for  brain tumours. .},
      url = {http://library.usi.edu/record/1484236},
      doi = {https://doi.org/10.1007/978-981-15-8473-2},
}