001484243 000__ 06454cam\\22006137i\4500 001484243 001__ 1484243 001484243 003__ OCoLC 001484243 005__ 20240117003318.0 001484243 006__ m\\\\\o\\d\\\\\\\\ 001484243 007__ cr\cn\nnnunnun 001484243 008__ 231124s2023\\\\si\\\\\\o\\\\\000\0\eng\d 001484243 019__ $$a1410592891 001484243 020__ $$a9789819949397$$qelectronic book 001484243 020__ $$a9819949394$$qelectronic book 001484243 020__ $$z9819949386 001484243 020__ $$z9789819949380 001484243 0247_ $$a10.1007/978-981-99-4939-7$$2doi 001484243 035__ $$aSP(OCoLC)1410493407 001484243 040__ $$aYDX$$beng$$erda$$cYDX$$dOCLCO$$dGW5XE$$dYDX$$dEBLCP$$dOCLCO 001484243 049__ $$aISEA 001484243 050_4 $$aTP248.27.P55$$bG45 2023 001484243 08204 $$a660.6$$223/eng/20231211 001484243 24500 $$aGenetic manipulation of secondary metabolites in medicinal plant /$$cRavi S. Singh, Nitish Kumar, editors. 001484243 264_1 $$aSingapore :$$bSpringer,$$c[2023] 001484243 300__ $$a1 online resource. 001484243 336__ $$atext$$btxt$$2rdacontent 001484243 337__ $$acomputer$$bc$$2rdamedia 001484243 338__ $$aonline resource$$bcr$$2rdacarrier 001484243 4901_ $$aInterdisciplinary biotechnological advances 001484243 5050_ $$aIntro -- Preface -- Acknowledgments -- Contents -- Chapter 1: Conventional Approaches Toward the Production of Bioactive Compounds from Medicinal Plants -- 1.1 Introduction -- 1.2 Medicinal Plants -- 1.3 Medicinal Plants Are Enriched with Bioactive Compounds -- 1.4 Major Areas of Bioactive Compounds -- 1.5 Production of Phytoceutical Compounds from Medicinal Plants -- 1.5.1 Increased Levels of Bioactive Compounds Through Different Farming Systems -- 1.5.2 Increased Levels of Bioactive Compounds Through Pruning Method 001484243 5058_ $$a1.5.3 Increased Levels of Bioactive Compounds Through Traditional Breeding Methods -- 1.6 Conclusion -- References -- Chapter 2: RNA Interference: Novel Technique for Enhancing Secondary Metabolite Production in Medicinal Plants -- 2.1 Introduction -- 2.2 RNA Interference: History and Principle -- 2.3 Core Components of RNA Interference Machinery -- 2.3.1 Dicer -- 2.3.2 Argonaute (AGO) Proteins -- 2.3.3 RNA-Dependent RNA Polymerase (RdRP) -- 2.4 Mechanism of RNA Interference -- 2.4.1 Generation of siRNAs -- 2.4.2 Degradation of Target mRNA -- 2.5 RNA Interference in Plants 001484243 5058_ $$a2.6 Application of RNA Interference in Enhancing Plant Secondary Metabolite Production in Plants -- 2.7 Advantages of RNA Interference -- 2.8 Limitations and Disadvantages of RNA Interference -- 2.9 Conclusion -- References -- Chapter 3: CRISPR/Cas9: A Novel Genetic Tool to Manipulate Plant Secondary Metabolite Pathways -- 3.1 Introduction -- 3.2 Applications of CRISPR in Medicinal Plants -- 3.2.1 Atropa belladonna -- 3.2.2 Cannabis sativa -- 3.2.3 Cichorium intybus L. -- 3.2.4 Dendrobium officinale -- 3.2.5 Dioscorea zingiberensis -- 3.2.6 Monochasma savatieri -- 3.2.7 Salvia miltiorrhiza 001484243 5058_ $$a3.2.8 Rehmannia glutinosa -- 3.2.9 Symphytum officinale -- 3.2.10 Papaver somniferum L. -- 3.3 Limitations of CRISPR/Cas9 Technique -- 3.4 Future Perspectives -- References -- Chapter 4: Enhancement of Plant Secondary Metabolites by Genetic Manipulation -- 4.1 Introduction -- 4.2 Genetic Manipulation for SM -- 4.2.1 Mutagenesis and Recombination -- 4.2.2 Chemical and Physical Mutagenesis -- 4.2.3 Manipulation of Biosynthesis Genes -- 4.2.4 Elicitation with Biotic and Abiotic Elicitor -- 4.2.5 Transcription Factors -- 4.2.6 Manipulation of Biosynthesis Gene Cluster or Cryptic Gene 001484243 5058_ $$a4.3 Cell Cultures as Biofactories -- 4.3.1 Metagenomics as a Source of Genetic Parts for SM Production in Bacteria -- 4.3.2 Heterologous Systems for SM Production -- 4.3.3 Plastid Manipulations -- 4.3.4 Glycosylation of Secondary Metabolites -- 4.3.5 Epigenetic Modifications -- 4.4 cDNA-AFLP as a Functional Genomics Tools -- 4.4.1 Modification of Translation Apparatus -- 4.4.2 Synthetic Biology -- 4.5 Conclusion and Future Perspective -- References -- Chapter 5: Role of Mutation and Stresses in the Production of Secondary Metabolite in Plants -- 5.1 Introduction -- 5.2 Plant Metabolites 001484243 506__ $$aAccess limited to authorized users. 001484243 520__ $$aThis book provides a comprehensive introduction and review of state-of-the-art biotechnological tools in enhancement of bioactive compounds in medicinal and aromatic plants. Plant bioactive compounds are plant-based natural products that display a variety of pharmacological applications. These bioactive compounds are important as medicines, pigments, flavorings and drugs because most of the pharmaceutical industries are highly dependent on medicinal plants and their extraction. The book introduces a systematic overview of state-of-the-art biotechnological techniques such as Omics, Crisper /Cas9 and RNAi to enhance the plant bioactive contents as well as enlists various in vitro techniques, hairy root culture and transgenic technology to enhance plant bioactive contents using plant tissue culture approaches. The book also provides an overview of the role of induced mutation, biotic and abiotic stress to increase the bioactive contents in plants and discusses the significant role of endophytes to enhance the contents of plant bioactive compound. The book also opens discussions related to standard operating procedures using hydroponics system of cultivation for significant enhancement of bioactive compound(s) and much more. This book serves as an excellent reference book for the researchers working in the field of plant secondary metabolites and pharmaceutical industries at global level. 001484243 588__ $$aDescription based on online resource; title from digital title page (viewed on December 12, 2023). 001484243 650_0 $$aPlant metabolites$$xBiotechnology. 001484243 650_0 $$aMedicinal plants$$xBiotechnology. 001484243 650_6 $$aPlantes$$xMétabolites$$xBiotechnologie. 001484243 650_6 $$aPlantes médicinales$$xBiotechnologie. 001484243 655_0 $$aElectronic books. 001484243 7001_ $$aSingh, Ravi S. 001484243 7001_ $$aKumar, Nitish. 001484243 77608 $$iPrint version: $$z9819949386$$z9789819949380$$w(OCoLC)1385401471 001484243 830_0 $$aInterdisciplinary biotechnological advances. 001484243 852__ $$bebk 001484243 85640 $$3Springer Nature$$uhttps://univsouthin.idm.oclc.org/login?url=https://link.springer.com/10.1007/978-981-99-4939-7$$zOnline Access$$91397441.1 001484243 909CO $$ooai:library.usi.edu:1484243$$pGLOBAL_SET 001484243 980__ $$aBIB 001484243 980__ $$aEBOOK 001484243 982__ $$aEbook 001484243 983__ $$aOnline 001484243 994__ $$a92$$bISE