Radiopharmaceutical therapy / Lisa Bodei, Jason S. Lewis, Brian M. Zeglis, editors.
Bodei, Lisa, editor.; Lewis, Jason (Jason S.), editor.; Zeglis, Brian Matthew, editor.
2023
RS431.R34
Available Online

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Title Radiopharmaceutical therapy / Lisa Bodei, Jason S. Lewis, Brian M. Zeglis, editors.
ISBN 9783031390050 (electronic bk.)
3031390059 (electronic bk.)
9783031397721
9783031390043
303139772X
3031390040
DOI https://doi.org/10.1007/978-3-031-39005-0
Published Cham, Switzerland : Springer, 2023.
Language English
Description 1 online resource (445 pages) : illustrations (black and white, and color).
Item Number 10.1007/978-3-031-39005-0 doi
Call Number RS431.R34
Dewey Decimal Classification 615.8/42
Summary This book covers foundational topics in the emerging field of radiopharmaceutical therapy. It is divided into three sections: fundamentals, deeper dives, and special topics. In the first section, the authors examine the field from a birds-eye view, covering topics including the history of radiopharmaceutical therapy, the radiobiology of radiopharmaceutical therapy, and the radiopharmaceutical chemistry of both metallic and non-metallic radionuclides. The second section provides a more in-depth look at specific radiotherapeutics. Chapters include broader discussions of the different platforms for radiopharmaceutical therapy as well as more focused case studies covering individual radiotherapeutics. The third and final section explores a number of areas for further study, including medical physics, artificial intelligence, in vivo pretargeting, theranostic imaging, and the regulatory review process for radiotherapeutics. This book is the first of its kind and is useful for a broad audience of scientists, researchers, physicians, and students across a range of fields, including biochemistry, cancer biology, nuclear medicine, radiology, and radiation oncology.
Access Note Access limited to authorized users.
Source of Description Description based on print version record.
Added Author Bodei, Lisa, editor.
Lewis, Jason (Jason S.), editor.
Zeglis, Brian Matthew, editor.
Available in Other Form RADIOPHARMACEUTICAL THERAPY.
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Preface
Foreword
Section 1. Fundamentals
Chapter 1. Introduction: The Case for Endoradiotherapy
Chapter 2. The History of Endoradiotherapy
Chapter 3. The Nuclear Chemistry of Therapeutic Radionuclides
Chapter 4. The Production of Therapeutic Radionuclides
Chapter 5. The Radiobiology of Alpha Particles, Beta Particles, and Auger Electrons
Chapter 6. The Radiopharmaceutical Chemistry of Metallic Radionuclides
Chapter 7. The Radiopharmaceutical Chemistry of Non-Metallic Radionuclides
Chapter 8. Dosimetry in Endoradiotherapy
Section 2. Deeper Dives
Chapter 9. Antibodies as Vectors for Endoradiotherapy
Chapter 10. Case Study #1: 225Ac-Labeled IgG
Chapter 11. Case Study #2: 131I-3F8
Chapter 12. Case Study #3: Antibody Fragments in Endoradiotherapy
Chapter 13. Peptides as Vectors for Endoradiotherapy
Chapter 14. Case Study #4: LUTATHERA
Chapter 15. Case Study #5: CXCR4
Chapter 16. Case Study #6: JR11
Chapter 17. Small Molecules as Vectors for Endoradiotherapy
Chapter 18. Case Study #7: PSMA-617
Chapter 19. Case Study #8: 223RaCl3
Section 3. Special Topics
Chapter 20. Auger Emitters in Endoradiotherapy
Chapter 21. In Vivo Pretargeting
Chapter 22. Theranostic Imaging and Endoradiotherapy
Chapter 23. The Next Generation of Therapeutic Radionuclides
Chapter 24. Artificial Intelligence and Machine Learning
Chapter 25. The Regulatory Review of Radiotherapeutics: USA
Chapter 26. The Regulatory Review of Radiotherapeutics: Europe
Chapter 27. The Regulatory Review of Radiotherapeutics: Japan
Chapter 28. Radiotherapeutics in the Nuclear Pharmacy
Chapter 29. The Future.

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