001484414 000__ 06002cam\\2200637\i\4500
001484414 001__ 1484414
001484414 003__ OCoLC
001484414 005__ 20240117003323.0
001484414 006__ m\\\\\o\\d\\\\\\\\
001484414 007__ cr\un\nnnunnun
001484414 008__ 231130s2023\\\\sz\a\\\\ob\\\\001\0\eng\d
001484414 019__ $$a1411308322
001484414 020__ $$a9783031452932$$q(electronic bk.)
001484414 020__ $$a3031452933$$q(electronic bk.)
001484414 020__ $$z3031452925
001484414 020__ $$z9783031452925
001484414 0247_ $$a10.1007/978-3-031-45293-2$$2doi
001484414 035__ $$aSP(OCoLC)1411017191
001484414 040__ $$aYDX$$beng$$erda$$epn$$cYDX$$dGW5XE$$dEBLCP$$dOCLCO
001484414 049__ $$aISEA
001484414 050_4 $$aQH324.2
001484414 08204 $$a570.285$$223/eng/20231213
001484414 24500 $$aIntroduction to bioinformatics in microbiology /$$cHenrik Christensen, editor.
001484414 250__ $$aSecond edition.
001484414 264_1 $$aCham :$$bSpringer,$$c[2023]
001484414 264_4 $$c©2023
001484414 300__ $$a1 online resource (xvi, 246 pages) :$$billustrations (chiefly color).
001484414 336__ $$atext$$btxt$$2rdacontent
001484414 337__ $$acomputer$$bc$$2rdamedia
001484414 338__ $$aonline resource$$bcr$$2rdacarrier
001484414 4901_ $$aLearning materials in biosciences
001484414 504__ $$aIncludes bibliographical references and index.
001484414 5050_ $$aIntro -- Preface to Second Edition -- Contents -- List of Abbreviations -- 1: Introduction -- 1.1 Basics and History of Bioinformatics -- 1.1.1 Bioinformatics Is Integrating Many Scientific Fields -- 1.1.2 Homology -- 1.1.3 Evolution Is Related to Sequence Diversity Caused by Mutations -- 1.2 The Aim, Structure, and Outline of the Book -- 1.3 Computers and Operating Systems Required for Bioinformatics -- 1.4 Computer Programs and Pipelines -- 1.5 Activity -- Further Reading -- Basic bioinformatics text books -- References -- 2: DNA Sequence Assembly and Annotation of Genes
001484414 5058_ $$a2.1 DNA Sequencing -- 2.1.1 Sanger Sequencing -- 2.1.2 Massive Parallel, Short-Read Sequencing -- 2.1.2.1 Illumina (Sequencing by Synthesis) -- 2.1.3 DNA Sequencing in Metagenomic and for Single Cell Sequencing -- 2.1.4 Real-Time, Single Molecule Sequencing -- 2.1.4.1 PacBio® -- 2.1.4.2 Nanopore Sequencing -- 2.2 DNA Sequence Assembly -- 2.2.1 Base Calling and Trimming -- 2.2.2 Assembly of DNA Sequences -- 2.2.2.1 Assembly by Overlap Consensus Methods -- 2.2.2.2 Assembly by k-mer Strategy -- 2.2.2.3 Quality Criteria of the Final Assembled DNA Sequence
001484414 5058_ $$a2.2.2.4 De Novo or with Reference -- 2.3 Closing of Genomes -- 2.4 DNA Sequence Formats -- 2.5 Annotation -- 2.5.1 Elements from Comparative Genomics Aiming Annotation -- 2.6 Activities -- 2.6.1 Annotation at RAST -- Further Reading -- References -- 3: Databases and Protein Structures -- 3.1 Introduction to Bioinformatics Databases -- 3.1.1 Data Formats Used with Bioinformatics Databases -- 3.2 Organization of Databases and Bioinformatics Institutions -- 3.3 Major Bioinformatics Databases -- 3.3.1 GenBank -- 3.3.2 The European Nucleotide Archive (ENA) -- 3.3.3 Swiss-Prot and UniProt
001484414 5058_ $$a3.3.4 Genomics Databases -- 3.3.5 Raw Sequence Read Datasets -- 3.3.6 Other Databases -- 3.3.7 Primary and Secondary Bioinformatics Databases -- 3.3.8 Data Formats in Bioinformatics Databases -- 3.4 Accession Numbers -- 3.5 Protein Structure Databases and Predictions -- 3.5.1 Primary and Secondary Structures -- 3.5.2 Domain Prediction and Databases -- 3.5.2.1 Single Motif -- 3.5.2.2 Multiple Motifs -- 3.5.2.3 Full Domain -- 3.5.2.4 Mixing Different Methods -- 3.5.3 Protein 3D Structure -- 3.6 Overview of Proteomics Databases and Servers -- 3.7 Help to Databases -- 3.8 Activities
001484414 5058_ $$a3.8.1 Download a Sequence from NCBI -- 3.8.2 Download a Genome from NCBI -- 3.8.3 Deposition of Sequence with GenBank -- 3.8.3.1 Procedure for Single DNA Sequences -- 3.8.3.2 Genomic Sequence -- 3.8.4 Protein Structure Prediction with Swiss Model and SPDBV -- 3.9 Example Illustrating Variable Information and Redundancy of a Primary Genomic Database and Comparison to Some Other Information in the Book -- References -- 4: Pairwise Alignment, Multiple Alignment, and BLAST -- 4.1 The Pairwise Alignment Problem -- 4.1.1 Global or Local Pairwise Alignments? -- 4.1.2 Substitution Matrices
001484414 506__ $$aAccess limited to authorized users.
001484414 520__ $$aThis updated and extended second edition of the textbook introduces the basic concepts of bioinformatics and enhances students' skills in the use of software and tools relevant to microbiology research. It discusses the most relevant methods for analysing data and teaches readers how to draw valid conclusions from the observations obtained. Free software and servers available on the Internet are presented in an updated version of 2023 and more advanced stand-alone software is proposed as a second option. In addition, new tools for microbial genome analysis and new flowcharts that complement the didactic elements have been added. Exercises and training questionnaires are included at the end of each chapter to facilitate learning. The book is aimed at Ph.D. students and advanced undergraduate students in microbiology, biotechnology, and (veterinary) medicine with little or basic knowledge of bioinformatics.
001484414 588__ $$aOnline resource; title from PDF title page (SpringerLink, viewed December 13, 2023).
001484414 650_6 $$aBio-informatique.
001484414 650_6 $$aMicrobiologie$$xInformatique.
001484414 650_0 $$aBioinformatics.$$vCongresses$$0(DLC)sh2007101998
001484414 650_0 $$aMicrobiology$$xData processing.$$xMicrobiology$$0(DLC)sh 85002572
001484414 655_0 $$aElectronic books.
001484414 7001_ $$aChristensen, Henrik,$$eeditor.
001484414 77608 $$iPrint version: $$z3031452925$$z9783031452925$$w(OCoLC)1395539480
001484414 830_0 $$aLearning materials in biosciences.
001484414 852__ $$bebk
001484414 85640 $$3Springer Nature$$uhttps://univsouthin.idm.oclc.org/login?url=https://link.springer.com/10.1007/978-3-031-45293-2$$zOnline Access$$91397441.1
001484414 909CO $$ooai:library.usi.edu:1484414$$pGLOBAL_SET
001484414 980__ $$aBIB
001484414 980__ $$aEBOOK
001484414 982__ $$aEbook
001484414 983__ $$aOnline
001484414 994__ $$a92$$bISE