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001484450 001__ 1484450
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001484450 020__ $$a9819969174$$q(electronic bk.)
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001484450 0247_ $$a10.1007/978-981-99-6917-3$$2doi
001484450 035__ $$aSP(OCoLC)1411277581
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001484450 050_4 $$aQD382.B5
001484450 08204 $$a547/.84$$223/eng/20231215
001484450 24500 $$aBlock co-polymeric nanocarriers :$$bdesign, concept, and therapeutic applications /$$cNeeraj Mishra, Vikas Pandey, editors.
001484450 264_1 $$aSingapore :$$bSpringer,$$c[2023]
001484450 264_4 $$c©2023
001484450 300__ $$a1 online resource (xvii, 429 pages) :$$billustrations
001484450 336__ $$atext$$btxt$$2rdacontent
001484450 337__ $$acomputer$$bc$$2rdamedia
001484450 338__ $$aonline resource$$bcr$$2rdacarrier
001484450 5050_ $$aIntro -- Preface -- Acknowledgment -- Contents -- Editors and Contributors -- 1: Development and Synthesis of Block Co-polymer and their Role in Nanotechnology -- 1.1 Introduction -- 1.1.1 Nomenclature -- 1.1.2 Physical Properties -- 1.1.3 Thermal Properties -- 1.1.4 Processability -- 1.1.5 Mechanical Properties -- 1.1.6 Optical Properties -- 1.1.7 Chemical Resistance -- 1.1.8 Transport Properties -- 1.1.9 Blending Properties -- 1.2 Classification of Block Copolymers -- 1.2.1 Based on Chain Length -- 1.2.1.1 Linear Block Copolymer -- 1.2.1.2 Nonlinear Block Copolymers
001484450 5058_ $$a1.2.1.3 Star-Block Copolymers -- 1.2.1.4 Miktoarm Star Copolymers -- 1.2.2 Based on Properties -- 1.2.2.1 Hydrophilic Block Copolymer -- 1.2.2.2 Hydrophobic Block Copolymers -- 1.2.2.3 Amphiphilic Block Copolymers -- 1.3 Synthesis of Block Copolymers with Distinct Structures Can Be Accomplished Using One of Three Main Methods -- 1.3.1 Living Polymerization by Sequential Additions of Different Monomers -- 1.3.2 Living Polymerization of the Original Polymer Chain Via the Addition of a Terminal End
001484450 5058_ $$a1.3.3 Via the Addition of Highly Reactive Functional Groups between Different Polymers in the Final Reaction Step -- 1.3.4 Living Polymerization by Sequential Additions of Different Monomers -- 1.3.4.1 Living Anionic Polymerization -- 1.3.4.2 Living Cationic Polymerization -- 1.3.4.3 Controlled/Living Radical Polymerization -- 1.3.4.4 Other Living Polymerizations Methods -- 1.4 Different Polymeric Formulations and their Pharmaceutical Applications -- 1.4.1 Micelles -- 1.4.2 Hydrogels -- 1.4.3 Polymersomes -- 1.4.4 Cubosomes -- 1.4.5 Other Nanostructure System -- 1.5 Conclusion -- References
001484450 5058_ $$a2: Role of Block Co-Polymers in Drug Delivery -- 2.1 Introduction -- 2.2 Polymeric Nanocarriers for Drug Delivery -- 2.2.1 Nanoparticles -- 2.2.2 Micelles -- 2.2.3 Hydrogel -- 2.3 Stimuli-Responsive Polymers for Drug Delivery -- 2.3.1 Temperature-Sensitive Drug Delivery Systems -- 2.3.2 Redox-Responsive Polymeric Drug Delivery Systems -- 2.3.3 Light-Responsive Polymeric Drug Delivery Systems -- 2.3.4 Enzyme-Sensitive Polymers -- 2.4 Conclusion and Future Prospects -- References -- 3: Role of Block Copolymers in the Enhancement of Poor Solubility of Drugs -- 3.1 Introduction
001484450 5058_ $$a3.2 Solubility Enhancement by Micelle Formation Using Block-Copolymer -- 3.3 Mechanism of Solubilization by Micelles -- 3.4 Latest Studies on Solubility Enhancement by Micelles Using Block Copolymers -- 3.5 Solubility Enhancement by Solid Dispersion Using Block Copolymer -- 3.6 Technique for Making Solid Dispersions (SDD) -- 3.7 Latest Studies on Solubility Enhancement by SDD Using Block Copolymers -- 3.8 Conclusion -- References -- 4: Synthesis and Self-Assembly of Block Copolymers -- 4.1 Introduction -- 4.2 Methodologies for Synthesis of Block Copolymers
001484450 506__ $$aAccess limited to authorized users.
001484450 520__ $$aThis book focuses on current advancements in the field of block copolymers and covers design, concept, and various therapeutic applications in the drug delivery. It also reviews the use of block copolymers in drug delivery applications from the development of sustained release products to smart polymeric delivery systems such as stimuli-responsive polymeric systems, for example, thermosensitive, redox-sensitive, photo-sensitive, and enzyme-sensitive. The book further discusses the nano assemblies from amphiphilic block copolymers as nanomedicine platforms for diagnosis and therapy due to their relatively small size, high drug loading capacity, controlled drug release, in vivo stability, and prolonged blood circulation. The chapters also review the various patents and ongoing clinical trials on the applications, covering several important new concepts and findings in the field of block copolymers. The book is aimed at researchers, academicians, and industrial scientists involved in the development of drug-delivery systems based on polymers.
001484450 588__ $$aOnline resource; title from PDF title page (SpringerLink, viewed December 15, 2023).
001484450 650_0 $$aBlock copolymers.
001484450 650_0 $$aDrug delivery systems.
001484450 650_6 $$aCopolymères séquencés.
001484450 650_6 $$aSystèmes d'administration de médicaments.
001484450 655_0 $$aElectronic books.
001484450 7001_ $$aMishra, Neeraj,$$eeditor.
001484450 7001_ $$aPandey, Vikas,$$eeditor.
001484450 77608 $$iPrint version: $$z9819969166$$z9789819969166$$w(OCoLC)1395945736
001484450 852__ $$bebk
001484450 85640 $$3Springer Nature$$uhttps://univsouthin.idm.oclc.org/login?url=https://link.springer.com/10.1007/978-981-99-6917-3$$zOnline Access$$91397441.1
001484450 909CO $$ooai:library.usi.edu:1484450$$pGLOBAL_SET
001484450 980__ $$aBIB
001484450 980__ $$aEBOOK
001484450 982__ $$aEbook
001484450 983__ $$aOnline
001484450 994__ $$a92$$bISE