Cover
Title
Copyright
End User License Agreement
Contents
Preface
CONSENT FOR PUBLICATION
CONFLICT OF INTEREST
ACKNOWLEDGEMENTS
Dedication
A Bit of History
Peter Hollands
A CHILD IS BORN
CONTROVERSY
OTHER OPTIONS FOR FERTILITY PATIENTS?
THE FIRST FERTILITY TREATMENTS
The First Technology
Fertility Treatment Today
Global IVF
Money!
'Breakthroughs'
Nobel Prize
Still Not A Cure
Population Growth
ADOPTION
PIONEERING TIMES
BLACK MONDAY
INPATIENTS AND REGULATION
MORE RECENTLY
INNOVATION
PROFIT AND 'ADD-ONS'
STAGNATION
THE FUTURE
KEY POINTS OF CHAPTER 1
The Female Patient
Peter Hollands
INTRODUCTION
FEMALE INFERTILITY
Blocked Tubes
Endometriosis
Polycystic Ovary Syndrome (PCOS)
Thyroid
Premature Menopause
Surgical Damage and Fibroids
Sterilisation
Medications
Other Causes of Infertility
Idiopathic Infertility
Stress!
'BACK-TO-BACK' TREATMENTS
A FINAL PRAYER
KEY POINTS OF CHAPTER 2
The Male Patient
Peter Hollands
INTRODUCTION
THE MALE ROLE IN FERTILITY TREATMENT
THE 'MEN'S ROOM' PORNOGRAPHY AND SEMEN ASSESSMENT
Hot Pants!
Testicular Damage
Vasectomy
Ejaculation and Psychosexual Disorders
Hormonal and Genetic Disorders
Medicines and Drugs
Life-style Issues
Stress
A FINAL PRAYER
KEY POINTS OF CHAPTER 3
The LGBT Patients
Peter Hollands
INTRODUCTION
SAME SEX FEMALE PATIENTS
Surrogacy for Same Sex Female Patients
Female Partner Providing Eggs for Treatment
SAME SEX MALE PATIENTS
Egg Donation and Surrogacy
Gender Re-Assignment
KEY POINTS OF CHAPTER 4
IVF Clinics
Peter Hollands
INTRODUCTION
MONEY!
PROFIT (OK, BUT NOT TOO MUCH!)
PUBLIC PROVISION OF IVF SERVICES (DIFFICULT TO DELIVER).

TREATMENT CYCLE NUMBERS (SIZE IS NOT EVERYTHING)
'FAMOUS' (OR INDEED INFAMOUS) CLINIC STAFF
IVF MARKETING (CAVEAT EMPTOR!)
IVF CLINIC STATISTICS (IS THAT BLACK ACTUALLY WHITE OR IS IT GREY?)
SERVICE (GOOD, BAD OR INDIFFERENT)
FERTILITY CLINIC FACILITIES
FERTILITY CLINIC STAFF
FERTILITY CLINIC TECHNOLOGY
QUESTIONS TO ASK A FERTILITY CLINIC
KEY POINTS OF CHAPTER 5
The Basic Treatment
Peter Hollands
INTRODUCTION
THE FERTILITY MEDICATIONS
FOLLICULAR GROWTH MONITORING
OVARIAN HYPER-STIMULATION SYNDROME
THE EGG COLLECTION
SEMEN PRODUCTION AND INSEMINATION
IVF FROM A LABORATORY VIEWPOINT
THE EMBRYO REPLACEMENT (TRANSFER)
EMBRYO FREEZING AND REPLACEMENT
THE PREGNANCY TEST AND THE DAY 35 SCAN
A 'PRECIOUS' PREGNANCY
DONOR GAMETES (DONOR SPERM AND DONOR EGGS)
Donor Sperm
Donor Sperm in IVF
Donor Eggs in IVF
KEY POINTS OF CHAPTER 6
The 'Add-Ons' Scandal
Peter Hollands
INTRODUCTION
IVF TECHNOLOGIES AND WORK PRACTICE
The 'Right' Patient
'Wobbly' Evidence
A 'Re-Boot' of IVF
TREATMENTS OF MALE INFERTILITY
'Catching Sperm'
'Add-ons'
Intracytoplasmic Sperm Injection (ICSI) and Related Technologies
Intracytoplasmic Morphologically Selected Sperm Injection (IMSI)
Physiological Intracytoplasmic Sperm Injection (PICSI)
Sperm DNA Fragmentation Testing
Time-Lapse Video Analysis of Embryonic Development
Pre-Implantation Genetic Screening (PGS) and Preimplantation Genetic Diagnosis (PGD)
Pre-Implantation Genetic Screening (Aneuploidy Screening)
Pre-Implantation Genetic Diagnosis (PGD)
Endometrial 'scratching' (Endometrial Injury)
Assisted Hatching
Embryo Glue
Elective Freeze All Cycles
Reproductive Immunology
Acupuncture
CONCLUSIONS ON 'ADD-ONS'
MISLEADING
COUNSELLING AND CLINICAL TRIALS.

STARTING FROM SCRATCH AND 'BLOBS'
KEY POINTS OF CHAPTER 7
The Regulators and Professional Societies
Peter Hollands
INTRODUCTION
POWER IS NOT ALWAYS A GOOD THING
UK REGULATION
THE ROLE OF A REGULATORY AUTHORITY
What Does the Regulatory Authority Regulate?
The European Society for Human Reproduction and Embryology (ESHRE)
KEY POINTS OF CHAPTER 8
The Patient 'Journey'
Peter Hollands
THE JOURNEY
First Things First
Time is Running Out!
The First Consultation
The Second and Nurse Consultation
At Last! The Treatment is Starting!
The Day of Egg Collection
Fertilisation Day and Onwards
Embryo Replacement (Transfer) Day
It's Freezing in Here!
Pregnancy Test Day
The Day 35 'Heart Beat Scan'
KEY POINTS OF CHAPTER 9
Advice to Fertility Patients
Peter Hollands
INTRODUCTION
MORE ADVICE ON ADVICE
Optimism and Electronic Advice
Clinic Counsellor
Who to Tell?
Family?
Friends?
Should I Tell People At Work?
Smoking, Alcohol, Obesity and Underweight
Smoking
Alcohol
Obesity
Back-to-Back Treatment Cycles
Egg Freezing: Good Idea, False Hope or Money-Making Machine?
Add-ons
Pregnancy, Birth and Parenthood
Pregnancy
Childbirth (Labour)
Parenthood
A Second Opinion?
CHANGING FERTILITY CLINICS?
INFERTILITY AND MENTAL HEALTH
IVF MYTHS
KEY POINTS OF CHAPTER 10
The Future of IVF
Peter Hollands
INTRODUCTION
FUTURE TECHNOLOGY
The Starting Point
Innovations
Profit!
Stagnation
A PROMISING FUTURE?
Telemedicine
INVOcell-A Possible Cheaper Version of IVF?
Laboratory Automation
Artificial Intelligence
Quantum Biology and Quantum Physics
PRP and Stem Cells
Embryonic Stem Cells and Hybrids
KEY POINTS OF CHAPTER 11
A Final Thought
Peter Hollands
INTRODUCTION
FERTILITY PATIENTS.

PHYSICIANS
CLINICAL EMBRYOLOGISTS
FERTILITY NURSES
CLINICS
CONCLUSION
KEY POINTS OF CHAPTER 12
Suggested Further Reading
USEFUL WEBSITES
Glossary
Subject Index
Back Cover.