TY  - GEN
N2  - In the United States, pregnant women have low concentrations of docosahexaenoic acid (DHA) and eicosapentaenoic acid (EPA), which are essential for fetal development. Although maternal blood provides accurate polyunsaturated fatty acid (PUFA) concentrations, venipuncture is expensive and not always accessible. PUFA-containing foods consumption, both omega-3 ad omega-6 is supposed to reflect in the status (plasma, RBC, adipose tissue) of docosahexaenoic acid (DHA) and eicosapentaenoic acid (EPA). De novo synthesis of DHA and EPA during pregnancy is supposed to be higher compared to pre and/or post-pregnancy periods. Thus, this study aimed to determine the association between maternal self-reported dietary intake of foods high in DHA and EPA, along with vegetable oils as a source of omega-6 fatty acids, with maternal blood DHA and EPA concentrations. Pregnant women (13–16 weeks gestation) were recruited and asked to complete a food-frequency questionnaire (FFQ) and blood draw at enrollment and 36 weeks. Circulating concentrations of DHA and EPA were quantified and change scores were calculated. Correlations were done to determine associations between FFQ results and EPA/DHA maternal blood concentrations. Regression analyses were run to examine significant predictors of the main outcomes. Overall, PUFA-food consumption and RBC’s DHA levels decreased from early to late pregnancy; self-reported PUFA-rich food consumption positively correlated with DHA and EPA levels. DHA concentration was predicted by self-reported PUFA-rich oils (sunflower/soy/corn/olive) consumption, but EPA concentration was predicted by maternal BMI. These findings suggest that EPA and DHA consumption decreased across pregnancy and the FFQ can be utilized as an effective method for estimating PUFA blood concentration during pregnancy.
AB  - In the United States, pregnant women have low concentrations of docosahexaenoic acid (DHA) and eicosapentaenoic acid (EPA), which are essential for fetal development. Although maternal blood provides accurate polyunsaturated fatty acid (PUFA) concentrations, venipuncture is expensive and not always accessible. PUFA-containing foods consumption, both omega-3 ad omega-6 is supposed to reflect in the status (plasma, RBC, adipose tissue) of docosahexaenoic acid (DHA) and eicosapentaenoic acid (EPA). De novo synthesis of DHA and EPA during pregnancy is supposed to be higher compared to pre and/or post-pregnancy periods. Thus, this study aimed to determine the association between maternal self-reported dietary intake of foods high in DHA and EPA, along with vegetable oils as a source of omega-6 fatty acids, with maternal blood DHA and EPA concentrations. Pregnant women (13–16 weeks gestation) were recruited and asked to complete a food-frequency questionnaire (FFQ) and blood draw at enrollment and 36 weeks. Circulating concentrations of DHA and EPA were quantified and change scores were calculated. Correlations were done to determine associations between FFQ results and EPA/DHA maternal blood concentrations. Regression analyses were run to examine significant predictors of the main outcomes. Overall, PUFA-food consumption and RBC’s DHA levels decreased from early to late pregnancy; self-reported PUFA-rich food consumption positively correlated with DHA and EPA levels. DHA concentration was predicted by self-reported PUFA-rich oils (sunflower/soy/corn/olive) consumption, but EPA concentration was predicted by maternal BMI. These findings suggest that EPA and DHA consumption decreased across pregnancy and the FFQ can be utilized as an effective method for estimating PUFA blood concentration during pregnancy.
AD  - Campbell University
AD  - East Carolina University
AD  - University of Southern Indiana
AD  - East Carolina University
AD  - East Carolina University
AD  - East Carolina University
AD  - East Carolina University
AD  - East Carolina University
AD  - University of Central Arkansas
AD  - Illinois State University
AD  -  East Carolina University
T1  - Self-Reported Intake and Circulating EPA and DHA Concentrations in US Pregnant Women
DA  - 2023-04-04
AU  - Lanier, Keri
AU  - Wisseman, Breanna
AU  - Strom, Cody J.
AU  - Johnston, Carol A.
AU  - Isler, Christy
AU  - DeVente, James
AU  - Newton, Edward
AU  - Pawlak, Roman
AU  - Allman-Tucker, Brittany A.
AU  - McDonald, Samantha
AU  - May, Linda E.
L1  - https://library.usi.edu/record/1488436/files/nutrients-15-01753-v3.pdf
LA  - eng
PY  - 2023-04-04
ID  - 1488436
L4  - https://library.usi.edu/record/1488436/files/nutrients-15-01753-v3.pdf
KW  - dietary assessment
KW  - food intake
KW  - polyunsaturated fatty acid
KW  - DHA
KW  - EPA
KW  - pregnancy
TI  - Self-Reported Intake and Circulating EPA and DHA Concentrations in US Pregnant Women
Y1  - 2023-04-04
L2  - https://library.usi.edu/record/1488436/files/nutrients-15-01753-v3.pdf
LK  - https://library.usi.edu/record/1488436/files/nutrients-15-01753-v3.pdf
UR  - https://library.usi.edu/record/1488436/files/nutrients-15-01753-v3.pdf
ER  -