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Details
Table of Contents
Background and approach to the study
Pesticide use
Pesticide control legislation
Approach to the study
Special characteristics of children
Growth
Development
Perinatal and pediatric toxicity
Acute toxicity
Neurotoxicity
Immunotoxicity
Carcinogenesis and mutagenesis
Metabolism and pharmacokinetics
Scaling and progression analysis
Methods for toxicity testing
Current methods: general considerations
Acute toxicity studies
Subchronic toxicity studies
Chronic toxicity studies
Developmental toxicity studies
Reproduction studies
Mutagenicity studies
General metabolism studies
Neurotoxicity studies
Special testing
Food and water consumption
Food consumption surveys
Survey methodology
Survey design
Sample weights
Sample size
Comparisons of intake data with standards
Validation of food consumption data
Strengths and weaknesses of the food consumption data bases in estimating pesticide exposure of children
Water intake
Quantification of consumption data
Age-related differences in dietary patterns.
(cont) Issues related to the evaluation of food monitoring data
Pesticide residues
Sources of data on usage
Ocurrence and fate of pesticide residues
Pesticide registration and the development of analytical methods
Methods for sampling and analysis
Monitoring
Quality controls
Limitations of the data
Pesticides in water
Pesticides in infant formula
Pesticides in human milk
Pesticides in foods
Estimating exposures
Use of food consumption and residue data for exposure assessment
Long-term exposure to benomyl
Short-term exposure to aldicarb
Multiple exposure assessment: organophosphate insecticides
Nondietary exposure to pesticides
Estimating the risks
General principles of risk assessment
Risk assessments for infants and children.
Pesticide use
Pesticide control legislation
Approach to the study
Special characteristics of children
Growth
Development
Perinatal and pediatric toxicity
Acute toxicity
Neurotoxicity
Immunotoxicity
Carcinogenesis and mutagenesis
Metabolism and pharmacokinetics
Scaling and progression analysis
Methods for toxicity testing
Current methods: general considerations
Acute toxicity studies
Subchronic toxicity studies
Chronic toxicity studies
Developmental toxicity studies
Reproduction studies
Mutagenicity studies
General metabolism studies
Neurotoxicity studies
Special testing
Food and water consumption
Food consumption surveys
Survey methodology
Survey design
Sample weights
Sample size
Comparisons of intake data with standards
Validation of food consumption data
Strengths and weaknesses of the food consumption data bases in estimating pesticide exposure of children
Water intake
Quantification of consumption data
Age-related differences in dietary patterns.
(cont) Issues related to the evaluation of food monitoring data
Pesticide residues
Sources of data on usage
Ocurrence and fate of pesticide residues
Pesticide registration and the development of analytical methods
Methods for sampling and analysis
Monitoring
Quality controls
Limitations of the data
Pesticides in water
Pesticides in infant formula
Pesticides in human milk
Pesticides in foods
Estimating exposures
Use of food consumption and residue data for exposure assessment
Long-term exposure to benomyl
Short-term exposure to aldicarb
Multiple exposure assessment: organophosphate insecticides
Nondietary exposure to pesticides
Estimating the risks
General principles of risk assessment
Risk assessments for infants and children.