Safe Handling of Hazardous Drugs (Fourth Edition).

Intro
Contents
Foreword
Definition of Hazardous Drugs
Key Points
Adverse Effects of Hazardous Drug Exposure
Key Points
Genotoxicity and Carcinogenicity of Hazardous Drug Exposure
Adverse Reproductive Health Outcomes of Occupational Hazardous Drug Exposure
Evidence for Occupational Hazardous Drug Exposure
Key Points
Biologic Monitoring
Environmental Monitoring
Interventions to Reduce Healthcare Worker Exposure
Key Points
Engineering Controls
Containment Supplemental Engineering Controls
Administrative Controls
Work Practice Controls
Personal Protective Equipment
Drug Compounding
Key Points
General Information
Containment Primary Engineering Control Work Practices
Limitations Specific to Class II Biosafety Cabinets
Personal Protective Equipment in a Containment Primary Engineering Control
Preparing to Work in a Containment Primary Engineering Control
Environmental Control Inside the Containment Primary Engineering Control
Compounding of Sterile Hazardous Drugs
Closed-System Drug-Transfer Devices
Negative-Pressure Technique
Spiking IV Bags and Priming Lines
Nonsterile Hazardous Drug Compounding
Robotic Compounding of Hazardous Drugs
Safety Measures: Drug Labeling and Signage
Receiving Hazardous Drugs
Disposal of Compounding Supplies
Drug Administration
Key Points
Intravenous Infusions
Intravenous Push Administration
Subcutaneous and Intramuscular Administration
Oral Administration
Enteral Tube Delivery
Topical Hazardous Drugs
Other Administration Routes
Other Settings for Hazardous Drug Administration
Postadministration Issues
Key Points
Urine and Feces
Other Routes of Exposure
Breastfeeding
Additional Safe Handling Strategies
Linen Handling
Key Points
Environmental Decontamination.

Key Points
Management of Spills
Key Points
Respiratory Protection During Spill Cleanup
Procedure for Cleanup of Hazardous Drug Spills
Acute Exposure
Follow-Up
Disposal of Hazardous Drugs and Hazardous Drug Waste
Key Points
Trace Hazardous Drug Waste
Managing Hazardous Waste Containers
Medical Surveillance of Healthcare Workers Handling Hazardous Drugs
Key Points
What Is Medical Surveillance?
Data Elements in a Medical Surveillance Program
Measures of Genotoxicity
Acute Exposure Follow-Up
Documentation
Essential Components for Medical Surveillance
Temporary Reassignment/Alternative Duty
Healthcare Worker Education and Training
Key Points
Educational Strategies
Adult Learning
Initial Education and Training
Periodic Education and Training
Healthcare Worker Education for Unique Routes of Administration and Settings
Informal Education
Innovative Strategies
Overcoming Barriers to Safe Handling Practices
Patient and Family Member/Caregiver Education
Key Points
Family Member and Caregiver Hazardous Drug Exposure
Content of Patient Education for Safe Handling
Routes of Exposure
Preventing Surface Contamination at Home
Personal Protective Equipment
Safe Handling of Oral Hazardous Drugs
Safe Handling Following Bladder Instillation
Linen Handling at Home
Hazardous Drug Spills in the Home
The Hazardous Drug Handling Policy Landscape
Key Points
Federal Efforts: Occupational Safety and Health Administration and National Institute for Occupatio
State Initiatives
Professional Organizations
Institutional Policy
Resources for Advocacy and Health Policy
Implications for Nursing
Appendices
Appendix A. Handling of Hazardous Drugs Healthcare Worker Agreement: Example
Appendix B. Hazardous Drug Safe Handling Checklist.

Appendix C. Hazardous Drug Administration Practicum
Appendix D. Safe Management of Hazardous Drugs in the Home for Patients and Family Members/Caregiver
References
Index.