Introduction
I. Gene discovery panel
Discovery of cancer susceptibility genes: study designs, analytic approaches, and trends in technology
II. Gene characterization panel
Design of gene characterization studies: on overview
Case-control studies of common alleles and environmental factors
Family-based associations studies
Cohort studies for characterizing measured genes
Multistage sampling for disease family registries
Detection of interaction involving identified genes: available study designs - Kin-cohort designs for gene characterization
III. Integration panel
Study design in genetic epidemiology: theoretical and practical considerations
Integrated designs for gene discovery and characterization
IV. Applications panel
Confirmation of prostate cancer susceptibility genes using high-risk families
Study-design issues in the development of the University of Southern California consortium's colorectal cancer family registry
Design and analysis issues in a population-based, case-control-family study of the genetic epidemiology of breast cancer and the co-operative family registry for breast cancer studies (CFRBCS)
Combined influence of genetic and dietary factors on colorectal cancer incidence in Japanese Americans.