000275244 000__ 02473cam\a22003734a\4500 000275244 001__ 275244 000275244 005__ 20210513103450.0 000275244 008__ 030206s2004\\\\njua\\\\\b\\\\001\0\eng\\ 000275244 010__ $$a 2003043077 000275244 0167_ $$a101181335$$2DNLM 000275244 019__ $$a53179003 000275244 020__ $$a0471434167 (pbk. : alk. paper) 000275244 035__ $$a(OCoLC)ocm51637651 000275244 035__ $$a275244 000275244 040__ $$aDLC$$cDLC$$dHAC$$dNLM 000275244 042__ $$apcc 000275244 049__ $$aISEA 000275244 05000 $$aQH442.2$$b.D75 2004 000275244 08200 $$a576.5$$221 000275244 1001_ $$aDrlica, Karl. 000275244 24510 $$aUnderstanding DNA and gene cloning :$$ba guide for the curious /$$cKarl Drlica. 000275244 250__ $$a4th ed. 000275244 260__ $$aHoboken, NJ :$$bWiley,$$cc2004. 000275244 300__ $$axiv, 369 p. :$$bill. ;$$c23 cm. 000275244 504__ $$aIncludes bibliographical references (p. 325-335) and index. 000275244 5050_ $$ach. 1. Preview: Life as interacting molecules -- PART I. BASIC MOLECULAR GENETICS. ch. 2. Structure of DNA: two long, interwound chains -- ch. 3. Reproducing DNA: information transfer from one generation to the next -- ch. 4. Gene expression: cellular use of genetic information -- PART II. MANIPULATING DNA. ch. 5. Microbial growth: one-celled organisms as tools for gene cloning -- ch. 6. Plasmids and phages: submicroscopic parasites used to deliver genes to cells -- ch. 7. Cutting and joining DNA: restriction endonucleases and ligases used to restructure DNA molecules -- ch. 8. Using complementary base pairing: hybridization, probes, and amplification using PCR -- ch. 9. Cloning genes: isolation of a hemoglobin gene -- ch. 10. Using cloned genes: gene structure, expression vectors, and gene function -- PART III. MODERN MOLECULAR GENETICS. ch. 11. Beyond the central dogma: a sampling of insights derived from gene cloning -- ch. 12. Retroviruses: AIDS and gene delivery -- ch. 13. Cancer genes: the loss of growth control -- PART IV: HUMAN GENETICS. ch. 14. Heredity: patterns of inheritance and genetic instability -- ch. 15. Application of human genetics: genetic testing, gene therapy, and DNA fingerprinting -- PART V. WHOLE GENOMES. ch. 16. Genomics: using whole genomes to study life. 000275244 650_0 $$aMolecular cloning. 000275244 650_0 $$aRecombinant DNA. 000275244 650_0 $$aGenetic engineering. 000275244 650_0 $$aGenetics. 000275244 65012 $$aCloning, Molecular. 000275244 85200 $$bgen$$hQH442.2$$i.D75$$i2004 000275244 85642 $$3Publisher description$$uhttp://www.loc.gov/catdir/description/wiley036/2003043077.html 000275244 85641 $$3Table of contents$$uhttp://www.loc.gov/catdir/toc/wiley032/2003043077.html 000275244 909CO $$ooai:library.usi.edu:275244$$pGLOBAL_SET 000275244 980__ $$aBIB 000275244 980__ $$aBOOK 000275244 994__ $$aE0$$bISE