000311085 000__ 02539cam\a22003134a\4500 000311085 001__ 311085 000311085 005__ 20210513113632.0 000311085 008__ 031124s2005\\\\nyua\\\\\b\\\\001\0\eng\\ 000311085 010__ $$a 2003025851 000311085 020__ $$a081666027 (alk. paper) 000311085 035__ $$a(OCoLC)ocm53814408 000311085 035__ $$a311085 000311085 040__ $$aDLC$$cDLC$$dOCO$$dXY4$$dC#P$$dXY4$$dOCL$$dBAKER$$dXY4$$dCOU$$dEHH$$dVP@$$dBTCTA$$dYDXCP 000311085 042__ $$apcc 000311085 049__ $$aISEA 000311085 05000 $$aRB155.8$$b.P36 2005 000311085 08200 $$a615.8/95 000311085 1001_ $$aPanno, Joseph. 000311085 24510 $$aGene therapy :$$btreating disease by repairing genes /$$cJoseph Panno. 000311085 260__ $$aNew York, NY :$$bFacts On File,$$cc2005. 000311085 300__ $$axvii, 172 p. :$$bill. ;$$c23 cm. 000311085 440_0 $$aFacts on File science library 000311085 4901_ $$aThe "new biology" series 000311085 504__ $$aIncludes bibliographical references (p. 151-155) and index. 000311085 5050_ $$aGenetic disorders -- Immune deficiencies -- Breast cancer -- Colon cancer -- Melanoma -- Cystic fibrosis -- Hemophilia -- Liver disease -- Cardiovascular disease -- Muscular dystrophy -- Alzheimer's disease -- Parkinson's disease -- Huntington's disease -- Viruses: the cornerstone of gene therapy -- Viruses are living crystals -- Viral genomes may be RNA or DNA -- Viruses evolved from plasmids -- Viruses know how to infect cells -- The virus as a gene vehicle -- Viruses used in gene therapy -- Ashi DeSilva: a promising start -- Clinical trials defined -- Cells of the immune system -- Adenosine deaminase (ADA) -- Preliminary research -- Clinical procedure for ADA gene therapy -- The DeSilva clinical trial -- Jesse Gelsinger: down to earth -- Ornithine transcarbamylase (OTC) -- Preliminary research -- Clinical procedure for OTC gene therapy -- The Gelsinger clinical trial -- The investigation -- Concluding remarks -- Future prospects -- Safer vehicles -- Reducing immune rejection of the vector -- Improved risk assessment -- Redesigning human anatomy and physiology -- Ethics of gene therapy -- The Belmont report -- Clinical trials -- Physiological enhancement -- Cosmetic applications -- Legal issues -- Regulatory agencies -- The Gelsinger legal trial -- International regulation -- Resource center -- Eucaryote cell primer -- Recombinant DNA primer -- The human genome project -- X-linked severe combined immunodeficiency (SCID-X1) -- Alzheimer's disease (AD) -- Huntington's disease (HD). 000311085 650_0 $$aGene therapy. 000311085 8001_ $$aPanno, Joseph.$$tNew biology. 000311085 85200 $$bgen$$hRB155.8$$i.P36$$i2005 000311085 85641 $$3Table of contents$$uhttp://www.loc.gov/catdir/toc/ecip0411/2003025851.html 000311085 909CO $$ooai:library.usi.edu:311085$$pGLOBAL_SET 000311085 980__ $$aBIB 000311085 980__ $$aBOOK 000311085 994__ $$aC0$$bISE