Preface
1. General principles of psychopharmacological treatment
General advice
Practice guidelines
Legal, ethical, and economic issues
Bibliography
2. Diagnosis and classifiction
Modd disorders
Bipolar disorders
Depressive disorders
Schizophrenia and other schizophrenia spectrum disorders
Anxiety disorders
Somatoform disorders
Personality disorders
Psychoactive substance use disorders
Child and adolescent disorders
FDA approval of symptom reduction strategies
DSM-V and pharmacogenetics
Summary
Bibliography
3. Antidepressants
History
General priciples of antidepressant use
Choosing an antidepressant
Dosage and administration
Duration of treatment
Selective serotonin reuptake inhibitors
Pharmacological effects
Indications
Side effects
Overdose
Drug interactions
Dosage and administration
Discontinuation
5-HT₂ receptor antagonists (Trazodone and Nefazodone)
Pharmacological effects
Indications
Side effects
Overdose
Drug interactions
Dosage and admdinistration
Discontinuation


Selective serotonin-norepinephrine reuptake inhibitors (Venlafaxine and Duloxetine)
Pharmacological effects
Indications
Side effects
Overdose
Drug interactions
Dosage and administration
Discontinuation
Combined noradrenergic-dopaminergic antidepressant (Bupropion)
Pharmacological effects
Indications
Side effects
Overdose
Drug interactions
Dosage and administration
Mirtazapine
Pharmacological effects
Indications
Side effects
Overdose
Drug interactions
Dosage and administration
Norepinephrine reuptake inhibitors : reboxetine and atomoxetine
Pharmacological effects
Indications
Side effects
Overdose
Drug interactions
Dosage and administration
Discontinuation
Gepirone
Tricyclic and tetracyclic antidepressants
Structures
Pharmacological effects
Indications
Blood levels
Side effects
Overdose
Dosage and administration
Discontinuation
Monoamine oxidase inhibitors
Pharmacological effects
Indications
Side effects
Overdose
Drug interactions
Dosage and administration
Discontinuation
Selective and reversible monoamine oxidase inhibitors
Melatonin agonist-5-HT₂c antagonist
Novel antidepressants
Bibliography


4. Antipsychotic drugs
General principles of antipsychotic use
The drugs
Efficacy
Acute antipsychotic treatment
Early inpatient treatment
Maintenance drug therapy
Use in other psychiatric disorders
Atypical antipsychotics
Clozapine
Risperidone
Olanzapine
Quetiapine
Zipradisone
Aripiprazole
Standard (typical) antipsychotics
Side effects
Haloperidol decanoate
Other options for treating negative symptoms
Alternatives to antipsychotic therapy
Antipsychotic drugs in development
Bibliography
5. Mood stabilizers
Lithium
History and indications
Pharmacological effects
Clinical indications
Side effects
Preparations
Dosage and administration
Use in pregnancy
Lithium Information Center
Anticonvulsants
Valproate
Carbamazepine
Lamotrigine
Other anticonvulsants
Antipsycholtics
Benzodiazepines
Calcium channel blockers
Omega-3 fatty acids
Bibliography
6. Antianxiety agents
Benzodiazepines
Indications
Pharmacological effects
Subclasses
Dosage and administration
Withdrawal
Side effects
Overdose
Antidepressants
Agoraphobia and panic
Generalized anxiety disorder
Social phobia
Body dysmorphic disorder
Posttraumatic stress disorder
Obsessive-compulsive disorder
Anticonvulsants
Antipsychotics
Noradrenergic agents
Clinical indications
Dosage and administration
Side effects


Antihistamines
Buspirone
Barbiturates
Amobarbital sodium (amytal) as a parenteral solution
Catatonia
Meprobamate
Bibliography
7. Hypnotics
Insomnia
Behavioral approaches
Pharmacological approaches
Benzodiazephine hypnotics
Nonbenzodiazephine hypnotics
Melatonin receptor agonist : Remelteon
Sedative antihistamines and other nonbenzodiazepine psychoactive drugs with hypnotic properties
Barbiturates
Nonbarbiturate hypnotics
Methaqualone
Over-the-counter sleeping agents
L-tryptophan
Melatonin
Valerian extract
General conclusions
Bibliography
8. Stimulants and other fast-acting drugs
Amphetamine abuse
Uses of stimulants
Attention-deficit/hyperactivity disorder
Depression
Acquired immunodeficiency syndrome
Other medical conditions
Drug combinations
Psychosis
Stimulant use versus abuse
Other fast-acting drugs
Bibliography


9. Augmentation strategies for treatment-resistant disorders
Augmentation strategies for depression
Lithium-antidepressant combinations
Thyroid supplement-antidepressant combinations
Estrogen, DHEA, and testosterone combinations with antidepressants
Dopamine agonist-antidepressant combinations
Monoamine precursor-antidepressant combinations
SSRI combinations
Antipsychotic-antidepressant combinations
Other TCA combinations
Augmentation strategies for bipolar disorder
Combinations of two or more mood stabilizers
Mood stabilizer-antipsychotic combinations
Mood stabilizer-antidepressant combinations
Mood stabilizers and omega-3 fatty acids
Augmentation strategies for schizophrenia
Combinations of two antipsychotics
Combinations of antidepressants and antipsychotics
Combinations of mood stabilizers and antipsychotics
Other augmentation strategies
Bibliography
10. Emergency room treatment
Agitation and violence
Depression and suicidality
Acute psychotic reactions
Mixed psychotic reactions
Schizophrenic, schizophreniform, and manic psychoses
Delirium
Severe anxiety
Stupor and catatonia
Emergency room referrals
Bibliography


11. Pharmacotherapy for substance use disorders
Drug testing
Stimulants
Opiates
Detoxification
Maintenance
Sedatives and hypnotics
Detoxification
Pentobarbital tolerance test
Benzodiazepines
Alcohol
Maintenance treatment
Cannabis
Hallucinogens
Phencyclidine
Bibliography
12. Pharmacotherapy in special situations
Pregnancy
Pediatric psychopharmacology
Stimulants
Antipsychotics
Antidepressants
Mood stabilizers
Antianxiety drugs
Geriatric psychopharmacology
Antidepressants
Hypnotics and anxiolytics
Mood stabilizers
Antipsychotics
Medications for dementia
Medications for agitation
Mental retardation
Medical conditions
Psychiatric disorders resulting from medical illness
Psychiatric disorders associated with nonpsychiatric drugs
Psychiatric disorders complicated by medical disorders
Conclusion
Bibliography


13. Herbals and dietary supplements
St. John's Wort (Hypericum perforatum)
Uses
Mechanism of action
Side effects and drug interactions
Dosage and administration
Omega-3 fatty acids
Uses and mechanism of action
Side effects and drug interactions
Dosage and administration
Kava (Piper methysticum)
Uses
Mechanism of action
Side effects and drug interactions
Dosage and administration
Valerian (Valeriana officinalis)
Uses
Mechanism of action
Side effects and drug interactions
Dosage and administration
Ginkgo (Ginkgo biloba)
Uses
Mechanism of action
Side effects and drug interactions
Dosage and administration
Folate and B vitamins
S-adenosylmethionine (SAMe)
Uses
Mechanism of action
Side effects and drug interactions
Dosage and administration
Inositol
Uses
Mechanism of action
Side effects and drug interactions
Dosage and administration


DHEA (dehydroepiandrosterone)
Uses
Mechanism of action
Side effects and drug interactions
Dosage and administration
Bibliography
Appendix A : Strengths and costs of antidepressant and antipsychotic drugs
Appendix B : Suggested readings
Index.