1. Background
About teamwork
Sources of error and epidemiologic thinking
Interpreting the relative value of studies
The HIV/AIDS epidemic today
2. Causes and sources of AIDS
Cytomegalovirus
Human T-cell lymphotropic virus type III (HTLV-III)
HIV-2, HTLV-IV (and...SIV and STLV...)
Does HIV-2 protect against HIV-1?
"Poppers" and Kaposi's Sarcoma
African seine fever virus
HIV does not cause AIDS
The source of HIV and AIDS
The River
Other theories
3. Counting cases
What is the future of AIDS? Modeling the past to estimate the future
Estimating the impact of AIDS
Idiopathic CD4-lymphocytopenia (ICL), or the "AIDS, not!" syndrome
HIV reporting
4. Epidemiologic controversies
Issues in sexual transmission
Blood and blood products
"Silent sequences"
A Florida dentist
"Safe" insemination
5. Unusual and unproven modes of HIV transmission
"No identified risk"
Health care workers
The environment
Insects
Belle Glade
Saliva and biting
Food
Sweat, tears, and urine
Household transmission
6. Issues in prevention
HIV testing
The person at risk, or the person known to be HIV-infected?
Preventing mother-to-infant spread
Needle and syringe exchange ; condom provision
Circumcision
7. Early drugs and biomedical interventions
The "pre-zidovudine" drugs
Experimental antiretroviral therapies now largely abandoned
Zidovudine
After zidovudine
8. The modern therapeutic era (after 1995)
When to start therapy in HIV-infected people without symptoms
Lipodystrophy
Protease inhibitors and cardiovascular disease
Early vaccines and microbicides
Strategic treatment interruptions
9. Errors, their consequences, and their management
Types of errors and their consequences
Human bias
Bureaucracy, the "killer bees," and other considerations about retarding research
Journals
Higher education
Appendix. Antiretroviral drugs approved by the U.S. Food and Drug Administration, 2007.