000363601 000__ 02020cam\a22003854a\4500 000363601 001__ 363601 000363601 005__ 20210513131636.0 000363601 006__ m\\\\\\\\u\\\\\\\\ 000363601 007__ cr\cn||||||||| 000363601 008__ 080527s2009\\\\njua\\\\sb\\\\001\0\eng\\ 000363601 010__ $$z 2008022807 000363601 0167_ $$z101474921$$2DNLM 000363601 020__ $$z0470229640 (cloth) 000363601 020__ $$z9780470229644 (cloth) 000363601 035__ $$a(CaPaEBR)ebr10275622 000363601 035__ $$a(OCoLC)646796105 000363601 040__ $$aCaPaEBR$$cCaPaEBR 000363601 05014 $$aRC677$$b.T87 2009eb 000363601 08204 $$a616.1/23061$$222 000363601 1001_ $$aTurner, J. Rick. 000363601 24510 $$aIntegrated cardiac safety$$h[electronic resource] :$$bassessment methodologies for noncardiac drugs in discovery, development, and postmarketing surveillance /$$cJ. Rick Turner, Todd A. Durham. 000363601 260__ $$aHoboken, N.J. :$$bJohn Wiley & Sons,$$cc2009. 000363601 300__ $$axxviii, 470 p. :$$bill. ;$$c25 cm. 000363601 504__ $$aIncludes bibliographical references (p. 397-455) and index. 000363601 5050_ $$aThe importance of cardiac safety assessments -- The biological basis of adverse drug reactions -- Cardiac structure and function -- Cardiac pathophysiology and disease -- Drug discovery and drug design -- Nonclinical development -- The thorough QT/QTc trial -- General safety assessments -- Therapeutic use trials and meta-analyses -- Assessment methodologies in nonexperimental postmarketing surveillance -- Postmarketing proarrhythmic cardiac safety assessments -- Generalized cardiac safety -- Medication errors, adherence, and concordance -- Future directions in drug safety. 000363601 506__ $$aAccess limited to authorized users. 000363601 650_0 $$aCardiovascular toxicology. 000363601 650_0 $$aHeart$$xEffect of drugs on. 000363601 650_0 $$aDrugs$$xSide effects$$xTesting. 000363601 650_0 $$aDrugs$$xSafety measures. 000363601 655_7 $$aElectronic books.$$2lcsh 000363601 7001_ $$aDurham, Todd A. 000363601 85280 $$bebk$$hProquest Ebook Central Academic Complete 000363601 85640 $$3ProQuest Ebook Central Academic Complete$$uhttps://univsouthin.idm.oclc.org/login?url=http://site.ebrary.com/lib/usiricelib/Doc?id=10275622$$zOnline Access 000363601 909CO $$ooai:library.usi.edu:363601$$pGLOBAL_SET 000363601 980__ $$aEBOOK 000363601 980__ $$aBIB 000363601 982__ $$aEbook 000363601 983__ $$aOnline