000424661 000__ 03226cam\a22003854a\4500 000424661 001__ 424661 000424661 005__ 20210513145927.0 000424661 006__ m\\\\\\\\u\\\\\\\\ 000424661 007__ cr\cn||||||||| 000424661 008__ 080303s2009\\\\njua\\\\sb\\\\001\0\eng\\ 000424661 010__ $$z 2008009573 000424661 0167_ $$z101467523$$2DNLM 000424661 020__ $$z9780470056097 (cloth) 000424661 020__ $$z0470056096 (cloth) 000424661 035__ $$a(CaPaEBR)ebr10296483 000424661 035__ $$a(OCoLC)647763421 000424661 040__ $$aCaPaEBR$$cCaPaEBR 000424661 05014 $$aRM301.8$$b.F67 2009eb 000424661 08204 $$a615/.1$$222 000424661 24500 $$aFormulation and analytical development for low-dose oral drug products$$h[electronic resource] /$$cedited by Jack Zheng. 000424661 260__ $$aHoboken, N.J. :$$bJohn Wiley & Sons,$$cc2009. 000424661 300__ $$axxiii, 461 p. :$$bill. ;$$c25 cm. 000424661 504__ $$aIncludes bibliographical references and index. 000424661 5050_ $$aAn overview / Jack Y. Zheng -- Challenges and strategies in formulation development of oral solid low-dose drug products / Jack Y. Zheng -- Particle size of drug substance and product content uniformity: theoretical considerations / Kevin C. Johnson -- Development of low-dose formulations using fluidized bed granulation / J. Joe Zhou, and Ralph Lipp -- Development of low-dose solid oral formulations using wet granulation / Ahmad Almaya -- Challenges in development and scale-up of low dose drug products by dry granulation: a case study / Mary T. Am Ende ... [et al.] -- Development of low-dose solid oral tablets using direct compression / Jack Y. Zheng and Robert L. Ternik -- Reduction of particle size of drug substance for low-dose drug products / Christopher L. Burcham ... [et al.] -- Function, quality, and regulations of pharmaceutical excipients for oral solid dosage forms / Jack Y. Zheng -- 000424661 5050_ $$aAnalytical method development: challenges and solutions for low-dose oral dosage forms / Beverly Nickerson ... [et al.] -- In vitro dissolution testing and method development / Vivian A. Gray, Jack Y. Zheng, and Norman N. Sesi -- Analysis of physical transformation of API during manufacture and storage / Gregory A. Stephenson -- Physical characterization tests for drug substances used in low-dose formulations / Ronald G. Lacocca -- An excipient library approach to analytical development for low-dose, solid oral dosage form drug products / Qing Chang ... [et al.] -- Cleaning verification for highly potent compounds / Brian W. Pack -- Containment challenges and strategies for potent compounds in the pharmaceutical industry / Victoria Cathcart, Sarah Jones, Beverly Nickerson -- Sample handling and containment in analytical testing laboratories / David Pattavina, Nancy Sage, Beverly Nickerson -- Regulatory considerations in the development of low-dose solid oral drug products / Ravi S. Harapanhalli. 000424661 506__ $$aAccess limited to authorized users. 000424661 650_0 $$aDrugs$$xDose-response relationship. 000424661 650_0 $$aDrugs$$xDosage. 000424661 650_0 $$aOral medication. 000424661 650_0 $$aDrug development. 000424661 655_7 $$aElectronic books.$$2lcsh 000424661 7001_ $$aZheng, Jack. 000424661 852__ $$bebk 000424661 85640 $$3ProQuest Ebook Central Academic Complete$$uhttps://univsouthin.idm.oclc.org/login?url=http://site.ebrary.com/lib/usiricelib/Doc?id=10296483$$zOnline Access 000424661 909CO $$ooai:library.usi.edu:424661$$pGLOBAL_SET 000424661 980__ $$aEBOOK 000424661 980__ $$aBIB 000424661 982__ $$aEbook 000424661 983__ $$aOnline