1. Parasites and humans. Mission impossible
Some lessons provided by yellow fever
Parasites in our times
Summary
2. The study of evolutionary parasitology. The evolutionary process
Questions about host-parasite interactions
Selection and units that evolve
Life history
Studying adaptations : optimality and evolutionarily stable strategies (ESS)
Comparative studies
Summary
3. The diversity and natural history of parasites. The ubiquity of parasites
A systematic overview of parasites
The evolution of parasitism
The diversity and evolution of parasite life-cycles
Summary
4. The natural history of defences. The defence sequence
Defence by the immune system
Basic elements of the immune defence
Immune defence protein families
The generation of diversity in recognition
The diversity of immune defences
Evolution of the immune system
Summary
5. Ecological immunology. Variation in parasitism
Ecological immunology : the costs of defence
The nature of defence costs
'Immunocompetence' and the benefits of defence
Strategies of immune defence
Tolerance as defence element
Summary
6. Parasites, immunity, and sexual selection. Differences between the sexes
Parasites and sexual selection
Sexual selection and immunity in invertebrates
Summary
7. Specificity. Measuring specificity and host range
Host-specificity of parasites
Evolution of the host range
Specific defences of the host
Memory, immune priming, and trans-generational transfer
Adaptive diversity and cross-reactivity
Summary


8. Parasite immune evasion and manipulation of host phenotype. Parasites manipulate their hosts
The diversity of immune-evasion mechanisms
Manipulation of the host phenotype to increase transmission
Manipulation of the host phenotype to increase infection lifetime
Mechanisms of host phenotype manipulation
Strategies of manipulation
Ecological significance of manipulation
Summary
9. Infection and pathogenesis. Infection and dose
Similar parasites cause different pathologies
Pathogenesis : the mechanisms of virulence
Immunopathology
The genetics of pathogenesis
Summary
10. Host-parasite genetics. The genetic architecture of host resistance
Evolutionary genetics of host-parasite interactions
Signatures of selection
Genetic structure of protozoan parasites
Summary
11. Epidemiology. Population biology of host-parasitoid systems
Epidemiology of infectious diseases : microparasites
Endemic infections and periodic outbreaks
Epidemiology of vectored microparasites
Epidemiology of macroparasites
Immuno-epidemiology
Epidemiology with evolutionary change
Within-host epidemiology
Summary
12. Virulence. Virulence
The evolution of virulence
Concepts of virulence evolution
Within-host evolution
Life history of infection events
Within- vs. between-host selection
Host population structure
Non-equilibrium virulence
Summary
13. Host-parasite (co-)evolution. Macro-evolution
Micro-evolution
Micro-evolution : the maintenance of diversity
Antagonistic co-evolution, sex, and recombination
The evolution of sex and recombination under parasitism
Selective sweeps
Summary
14. Ecology. Parasites and host life-history
Host populations
Host ecological communities
Parasite ecology
Invasions
Summary.