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000434632 010__ $$a  2011001258
000434632 019__ $$a671466195
000434632 020__ $$a9781936113194 (hard cover : alk. paper)
000434632 020__ $$a1936113198 (hard cover : alk. paper)
000434632 0248_ $$a40019764290
000434632 035__ $$a(OCoLC)ocn698029439
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000434632 042__ $$apcc
000434632 049__ $$aISEA
000434632 05000 $$aQP623$$b.D37 2011
000434632 08200 $$a572.8/8$$222
000434632 1001_ $$aDarnell, James E.
000434632 24510 $$aRNA :$$blife's indispensable molecule /$$cJames Darnell.
000434632 260__ $$aCold Spring Harbor, N.Y. :$$bCold Spring Harbor Laboratory Press,$$cc2011.
000434632 300__ $$axiv, 416 p. :$$bill. (some col.) ;$$c24 cm.
000434632 504__ $$aIncludes bibliographical references (p. 397-398) and index.
000434632 5050_ $$aThe dawn of molecular biology : history of macromolecules before RNA -- RNA connects genes and proteins : ribosomes, tRNA, and messenger RNA -- After mRNA : the genetic code, translation, and the biochemistry of controlled RNA synthesis in bacteria -- Gene expression in mammalian cells : discovery of RNA processing, genes in pieces, and new RNA chemistry -- Controlling mRNA : the cell's most complicated task -- RNA and the beginning of life.
000434632 520__ $$aIn this textbook the author provides an account of RNA research, illuminated by his own life-long engagement in the field. He describes how scientists unraveled fundamental questions about the biochemical and genetic importance of RNA, how mRNAs are generated and used to produce proteins, how noncoding and catalytic RNAs mediate key cellular processes, and how RNA molecules likely initiated life on Earth. With a scope extending from the early 20th century to the present day, he conveys the intellectual context in which these questions first arose and explains how the key experiments were structured and answers obtained. The book is geared towards scientists from the graduate level on up.
000434632 650_0 $$aRNA.
000434632 65012 $$aRNA.
000434632 65022 $$aMolecular Biology$$xhistory.
000434632 8528_ $$bacq$$hCANCEL
000434632 909CO $$ooai:library.usi.edu:434632$$pGLOBAL_SET
000434632 980__ $$aBIB