000440978 000__ 02581cam\a2200361\a\4500 000440978 001__ 440978 000440978 005__ 20210513153355.0 000440978 006__ m\\\\\o\\d\\\\\\\\ 000440978 007__ cr\cnunnnunnun 000440978 008__ 100706s2011\\\\njuaf\\\ob\\\\001\0\eng\d 000440978 010__ $$z 2010028355 000440978 020__ $$z9780470499467 000440978 020__ $$a9780470933930 (electronic book) 000440978 035__ $$a(CaPaEBR)ebr10441397 000440978 035__ $$a(OCoLC)708563222 000440978 040__ $$aCaPaEBR$$cCaPaEBR 000440978 05014 $$aRB155$$b.G3584 2011eb 000440978 08204 $$a616/.042$$222 000440978 24500 $$aGene discovery for disease models$$h[electronic resource] /$$cedited by Weikuan Gu. 000440978 260__ $$aHoboken, N.J. :$$bWiley,$$cc2011. 000440978 300__ $$a1 online resource (xiii, 537 p., [15] p. of plates) :$$bcol. ill. 000440978 504__ $$aIncludes bibliographical references and index. 000440978 5050_ $$aIntroduction : gene discovery-from positional cloning to genomic cloning -- High throughput gene expression analysis and the identification of expression QTLs -- DNA methylation in the pathogenesis of autoimmunity -- Ccell-based analysis with microfluidic chip -- Missing dimension : protein turnover rate measurement in gene discovery -- Bioinformatics tools for the prediction of gene function -- Determination of genomic locations of targeted genetic loci -- Mutation discovery using high throughput mutation screening technology -- Candidate screening through gene expression profile -- Candidate screening through high-density SNP array -- Gene discovery through direct genome sequencing -- Candidate screening through bioinformatics tools -- Using an integrative strategy to identify mutations -- Determination of the function of a mutant in a gene -- Confirmation of a mutation by multiple molecular approaches -- Confirmation of a mutation by microRNA -- Confirmation of function of a gene by translational approaches -- Confirmation of single nucleotide mutations -- Initial identification and confirmation of a QTL gene -- Gene discovery of crop diseases in the post genome era -- Impact of whole genome genetic element analysis on gene discovery of disease models -- Impact of whole genome protein analysis on gene discovery of disease models. 000440978 506__ $$aAccess limited to authorized users. 000440978 650_0 $$aMedical genetics. 000440978 650_0 $$aMutation (Biology) 000440978 650_0 $$aGenomics. 000440978 650_0 $$aGenetic disorders. 000440978 650_0 $$aElectronic books. 000440978 7001_ $$aGu, Weikuan. 000440978 85280 $$bebk$$hProquest Ebook Central Academic Complete 000440978 85640 $$3ProQuest Ebook Central Academic Complete$$uhttps://univsouthin.idm.oclc.org/login?url=http://site.ebrary.com/lib/usiricelib/Doc?id=10441397$$zOnline Access 000440978 909CO $$ooai:library.usi.edu:440978$$pGLOBAL_SET 000440978 980__ $$aEBOOK 000440978 980__ $$aBIB 000440978 982__ $$aEbook 000440978 983__ $$aOnline