(Publisher-supplied data) Part I Basic Concepts of Drug Metabolism and Disposition
The Progression of Drug Metabolism
Common Biotransformation Reactions
Metabolic Activation of Organic Functional Groups Utilized in Medicinal Chemistry
Drug Metabolizing Enzymes, Transporters and Drug-Drug Interactions
Experimental Models of Drug Metabolism and Disposition
Principles of Pharmacokinetics: Predicting Human Pharmacokinetics
Drug Metabolism Research as an Integral Part of the Drug Discovery and Development Processes
Part II Mass Spectrometry in Drug Metabolism: Principles and Common Practice
Theory and Instrumentation of Mass Spectrometry
Common Liquid Chromatography-Mass Spectrometry (LC-MS) Methodology for Metabolite Identification
Mass Spectral Interpretation
Techniques to Facilitate the Performance of Mass Spectrometry: Sample Preparation, Liquid Chromatography and Non-Mass Spectrometric Detection
Part III Applications of New LC/MS Techniques in Drug Metabolism and Disposition
Quantitative In Vitro ADME Assays using LC-MS as a Part of Early Drug Metabolism Screening
High Resolution Mass Spectrometry and Drug Metabolite Identification
Distribution Studies of Drugs and Metabolites in Tissue by Mass Spectrometric Imaging
Use of Triple Quadrupole-Linear Ion Trap Mass Spectrometry as a Single LC/MS Platform in Drug Metabolism and Pharmacokinetics Studies
Quantitative Drug Metabolism with Accelerator Mass Spectrometry
Standard-Free Estimation of Metabolite Levels Using Nanospray Mass Spectrometry: Current Statutes and Future Directions
Profiling and Characterization of Herbal Medicine and their Metabolites using LC-MS
Liquid Chromatography Mass Spectrometry Bioanalysis of Proteins in Biological Matrices
Mass Spectrometry in the Analysis of DNA, Protein, Peptide, and Lipid Biomarkers of Oxidative Stress
LC-MS in Endogenous Metabolite Profiling and Small Molecule Biomarker Discovery.