000442199 000__ 02742cam\a2200397\a\4500 000442199 001__ 442199 000442199 005__ 20210513153657.0 000442199 006__ m\\\\\o\\d\\\\\\\\ 000442199 007__ cr\cnunnnunnun 000442199 008__ 101015s2011\\\\njuadf\\ob\\\\001\0\eng\d 000442199 010__ $$z 2010043286 000442199 020__ $$z9780470449820 000442199 020__ $$z9781118001042 (oBook) 000442199 020__ $$z9781118001035 (ePDF) 000442199 020__ $$z9781118008980 (ePub) 000442199 020__ $$a9781118001035 (electronic bk.) 000442199 035__ $$a(CaPaEBR)ebr10494674 000442199 035__ $$a(OCoLC)759159342 000442199 040__ $$aCaPaEBR$$cCaPaEBR 000442199 05014 $$aRA1224.3$$b.B68 2011eb 000442199 08204 $$a616/.042$$222 000442199 24500 $$aApplications of toxicogenomics in safety evaluation and risk assessment$$h[electronic resource] /$$cedited by Darrell R. Boverhof, B. Bhaskar Gollapudi. 000442199 260__ $$aHoboken, N.J. :$$bJohn Wiley & Sons,$$cc2011. 000442199 300__ $$a1 online resource (xiii, 377 p., [8] p. of plates) :$$bill. (some col.) 000442199 504__ $$aIncludes bibliographical references and index. 000442199 5050_ $$aToxicology, "omics" technologies, and toxicogenomics : a primer -- Introduction to human health risk assessment -- Practical considerations for the application of toxicogenomics to risk assessment--early experience, current drivers, and a path forward -- Approaches and practical considerations for the analysis of toxicogenomics data -- Genomics in identifying mutagenic mode of action in carcinogenesis -- Application of genomics for predicting and understanding the mode of action for non-genotoxic carcinogens -- Genomics in characterizing endocrine toxicity -- Studying organ specific toxicity using gene expression profiling -- Toxicogenomic studies in human populations -- Toxicogenomics applied to ecological risk assessment -- Analysis of transcriptomic dose response data for toxicology and risk assessment -- Toxicogenomics as a tool for validating animal to human extrapolations in chemical risk assessment: concepts, applications and challenges -- Toxicogenomics and animal alternatives -- Toxicogenomics and the regulatory framework -- Standardization of gene expression information for the safety evaluation--activities in Japan - -- Applying transcriptional profiling in drug safety evaluation -- Reframing the risk assessment paradigm : towards a systems biology approach. 000442199 506__ $$aAccess limited to authorized users. 000442199 650_0 $$aGenetic toxicology. 000442199 650_0 $$aToxicity testing. 000442199 650_0 $$aHealth risk assessment. 000442199 650_0 $$aElectronic books. 000442199 7001_ $$aBoverhof, Darrell R. 000442199 7001_ $$aGollapudi, B. Bhaskar. 000442199 85280 $$bebk$$hProquest Ebook Central Academic Complete 000442199 85640 $$3ProQuest Ebook Central Academic Complete$$uhttps://univsouthin.idm.oclc.org/login?url=http://site.ebrary.com/lib/usiricelib/Doc?id=10494674$$zOnline Access 000442199 909CO $$ooai:library.usi.edu:442199$$pGLOBAL_SET 000442199 980__ $$aEBOOK 000442199 980__ $$aBIB 000442199 982__ $$aEbook 000442199 983__ $$aOnline