000444203 000__ 02511cam\a2200373\a\4500 000444203 001__ 444203 000444203 005__ 20210513154043.0 000444203 006__ m\\\\\\\\u\\\\\\\\ 000444203 007__ cr\cn||||||||| 000444203 008__ 110408s2011\\\\njuad\\\sb\\\\001\0\eng\d 000444203 010__ $$z 2011015205 000444203 020__ $$z9780470414118 (cloth) 000444203 020__ $$z9781118084410 (oIBSN) 000444203 020__ $$z9781118084403 (ePub) 000444203 020__ $$z9781118084397 (e-book) 000444203 035__ $$a(CaPaEBR)ebr10483221 000444203 035__ $$a(OCoLC)747411897 000444203 040__ $$aCaPaEBR$$cCaPaEBR 000444203 05014 $$aQP601$$b.S5685 2011eb 000444203 08204 $$a572/.7$$223 000444203 1001_ $$aStein, Ross L. 000444203 24510 $$aKinetics of enzyme action$$h[electronic resource] :$$bessential principles for drug hunters /$$cRoss L. Stein. 000444203 260__ $$aHoboken, N.J. :$$bWiley,$$cc2011. 000444203 300__ $$axii, 302 p. :$$bill. 000444203 504__ $$aIncludes bibliographical references and index. 000444203 5050_ $$aKinetics of single-substrate enzymatic reactions -- Kinetics of single-substrate enzymatic reactions : special topics -- Enzyme inhibition : the phenomenon and mechanistic analysis -- Kinetic mechanism of inhibition of one-substrate enzymatic reactions -- Tight-binding, slow-binding, and irreversible inhibitors -- Kinetics of two-substrate enzymatic reactions -- Kinetic mechanism of inhibition of two-substrate enzymatic reactions -- Allosteric modulation of enzyme-catalyzed reactions -- Kinetics-based probes of enzyme mechanisms. 000444203 506__ $$aAccess limited to authorized users. 000444203 520__ $$a"Few scientists have the knowledge to perform the studies that are necessary to discover and characterize enzyme inhibitors, despite the vested interest the pharmaceutical industry has in this field. Beginning with the most basic principles pertaining to simple, one-substrate enzyme reactions and their inhibitors, and progressing to a thorough treatment of two-substrate enzymes, Kinetics of Enzyme Action: Essential Principles for Drug Hunters provides biochemists, medicinal chemists, and pharmaceutical scientists with numerous case study examples to outline the tools and techniques necessary to perform, understand, and interpret detailed kinetic studies for drug discovery"--Provided by publisher. 000444203 650_0 $$aEnzymes$$xPharmacokinetics. 000444203 650_0 $$aEnzyme inhibitors$$xPharmacokinetics. 000444203 655_7 $$aElectronic books.$$2lcsh 000444203 852__ $$bebk 000444203 85640 $$3ProQuest Ebook Central Academic Complete$$uhttps://univsouthin.idm.oclc.org/login?url=http://site.ebrary.com/lib/usiricelib/Doc?id=10483221$$zOnline Access 000444203 909CO $$ooai:library.usi.edu:444203$$pGLOBAL_SET 000444203 980__ $$aEBOOK 000444203 980__ $$aBIB 000444203 982__ $$aEbook 000444203 983__ $$aOnline