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The beginning of computational genomics
Finding sequence similarities
Homology: can we get it right?
Getting ready for the era of comparative genomics: the importance of viruses
The first fact of comparative genomics: protein sequences are remarkably resilient in evolution
The second fact of comparative genomics: functional convergence at the molecular level
Prediction of function and reconstruction of metabolism from genomic data: homology-based approaches
Prediction of function and reconstruction of metabolism: post-homology approaches
Structural genomics: what does it tell us about life?
How many protein families are there?
Phylogenetic inference and the era of complete genomes
Two stories about evolution
Minimal and ancestral genomes
Comparative genomics and systems biology.

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