Introduction
Theoretical framework I : solubility
Theoretical framework II : dissolution
Theoretical framework III : biological membrane permeation
Theoretical framework IV : gastrointestinal transit models and integration
Physiology of gastrointestinal tract and other administration sites in humans and animals
Drug parameters
Validation of mechanistic models
Bioequivalence and biopharmaceutical classification system
Dose and particle size dependency
Enabling formulations
Food effect
Biopharmaceutical modeling for miscellaneous cases
Intestinal transporters
Strategy in drug discovery and development
Epistemology of biopharmaceutical modeling and good simulation practice.