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000695388 019__ $$a859589402
000695388 020__ $$a9781461480396 $$qelectronic book
000695388 020__ $$a1461480396 $$qelectronic book
000695388 020__ $$z9781461480389
000695388 0247_ $$a10.1007/978-1-4614-8039-6$$2doi
000695388 035__ $$aSP(OCoLC)ocn858763767
000695388 035__ $$aSP(OCoLC)858763767$$z(OCoLC)859589402
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000695388 049__ $$aISEA
000695388 050_4 $$aRC268.4$$b.N83 2014
000695388 08204 $$a616.99/406$$223
000695388 24500 $$aNuclear signaling pathways and targeting transcription in cancer$$h[electronic resource] /$$cRakesh Kumar, editor.
000695388 260__ $$a[Totowa, N.J.] :$$bHumana Press,$$c©2014.
000695388 300__ $$a1 online resource (xii, 439 pages) :$$billustrations (some color).
000695388 336__ $$atext$$btxt$$2rdacontent
000695388 337__ $$acomputer$$bc$$2rdamedia
000695388 338__ $$aonline resource$$bcr$$2rdacarrier
000695388 347__ $$atext file$$bPDF$$2rda
000695388 4901_ $$aCancer drug discovery and development,$$x2196-9906
000695388 504__ $$aIncludes bibliographical references and index.
000695388 5050_ $$aPreface -- Steroid Receptor Coactivators (SRCs) as Integrators of Multiple Signaling Pathways in Cancer Progression -- Role of Alteration/Deficiency in Activation (ADA) Complex in the Cell Cycle, Genomic Instability and Cancer -- RUNX2 Transcriptional Regulation in Development and Disease -- Epigenetic Mechanisms of Cancer Metastasis -- Regulatory Effects of Arsenic on Cellular Signaling Pathways: Biological Effects and Therapeutic Implications -- Nuclear Factors Linking Cancer and Inflammation -- Regulation of the Jak/STATs Pathways by Histone Deacetylases -- Receptor Tyrosine Kinases in the Nucleus: Nuclear Functions and Therapeutic Implications in Cancers -- Nucleolar Signaling Determines Cell Fate The RP-Mdm2-p53 Axis Fine-Tunes Cellular Homeostasis -- Transcriptional Regulation of Lipogenesis as a Therapeutic Target for Cancer Treatment -- Selective Inhibition of Acetyl-Lysine Effector Domains of the Bromodomain Family in Oncology -- Domain Specific Targeting of Cancer -- The Potential of Targeting Splicing for Cancer Therapy -- Exploiting Cell Cycle Pathways in Cancer Therapy: New (and Old) Targets and Potential Strategies -- Histone Demethylases in Prostate Cancer -- Therapeutic Significance of Chromatin Remodeling Complexes in Cancer -- Index.
000695388 506__ $$aAccess limited to authorized users.
000695388 520__ $$aAt the moment, there is no dedicated book to summarize the roles, the significance, and potential therapeutic targeting of transcriptional factors from the perspective of signaling cascade, and thus, directly impacting the functionality of transcriptional factors in cancer. In addition, this book will offer a comprehensive basic and clinical science behind the functions of representative core transcriptional factors. These chapters will serve as a treasure for all those who have an interest in the basis, progression, and targeting of human cancer.
000695388 588__ $$aDescription based on print version record.
000695388 650_0 $$aTranscription factors.
000695388 650_0 $$aCancer$$xGenetic aspects.
000695388 650_0 $$aCancer$$xTreatment.
000695388 7001_ $$aKumar, Rakesh$$c(Professor of Biotechnology)
000695388 77608 $$iPrint version:$$aKumar, Rakesh.$$tNuclear Signaling Pathways and Targeting Transcription in Cancer.$$dDordrecht : Springer, ©2013$$z9781461480389
000695388 830_0 $$aCancer drug discovery and development.
000695388 85280 $$bebk$$hSpringerLink
000695388 85640 $$3SpringerLink$$uhttps://univsouthin.idm.oclc.org/login?url=http://dx.doi.org/10.1007/978-1-4614-8039-6$$zOnline Access
000695388 909CO $$ooai:library.usi.edu:695388$$pGLOBAL_SET
000695388 980__ $$aEBOOK
000695388 980__ $$aBIB
000695388 982__ $$aEbook
000695388 983__ $$aOnline
000695388 994__ $$a92$$bISE