000695423 000__ 02797cam\a2200445Ii\4500 000695423 001__ 695423 000695423 005__ 20230306135438.0 000695423 006__ m\\\\\o\\d\\\\\\\\ 000695423 007__ cr\cnu---unuuu 000695423 008__ 130926t20132014au\a\\\\o\\\\\001\0\eng\d 000695423 020__ $$a9783709106877 $$qelectronic book 000695423 020__ $$a3709106877 $$qelectronic book 000695423 020__ $$z9783709106860 000695423 0247_ $$a10.1007/978-3-7091-0687-7$$2doi 000695423 035__ $$aSP(OCoLC)ocn858939342 000695423 035__ $$aSP(OCoLC)858939342 000695423 040__ $$aGW5XE$$beng$$erda$$epn$$cGW5XE$$dYDXCP$$dN$T$$dVAM$$dCOO$$dOHS$$dOCLCO 000695423 049__ $$aISEA 000695423 050_4 $$aRC394.D35$$b.M85 2013 000695423 08204 $$a616.8$$223 000695423 24500 $$aMultiple system atrophy$$h[electronic resource] /$$cGregor Wenning, Alessandra Fanciulli, editors. 000695423 264_1 $$aVienna :$$bSpringer,$$c[2013?] 000695423 264_4 $$c©2014 000695423 300__ $$a1 online resource (xvi, 198 pages) :$$bcolor illustrations. 000695423 336__ $$atext$$btxt$$2rdacontent 000695423 337__ $$acomputer$$bc$$2rdamedia 000695423 338__ $$aonline resource$$bcr$$2rdacarrier 000695423 500__ $$aIncludes index. 000695423 5050_ $$a1. Historical Review -- 2. Epidemiology -- 3. Neuropathology -- 4. Etiopathogenesis -- 5. Animal Models -- 6. Clinical Presentation -- 7. Clinical diagnostic Criteria -- 8. Natural History -- 9. Investigations -- 10. Treatment. 000695423 506__ $$aAccess limited to authorized users. 000695423 520__ $$aThis textbook provides a comprehensive monography on multiple system atrophy (MSA), a rare and fatal neurodegenerative disorder that presents with autonomic failure and either parkinsonism (MSA-P) or cerebellar ataxia (MSA-C).The underlying neuropathology of MSA is characterized by striatonigral degeneration (SND), olivopontocerebellar atrophy (OPCA) and unique oligodendroglial cytoplasmic alpha-synuclein inclusions. MSA is therefore classified among the alpha-synucleinopathies such as Parkinson's disease, pure autonomic failure and dementia with Lewy bodies. Over the last decade there have been important advances in early diagnosis, pathogenesis research and clinical trial activity. The monography will cover the entire spectrum ranging from molecular and genetic work to symptomatic and interventional therapies. The book is written for movement disorder clinicians and basic neuroscientists interested in degenerative movement disorders. 000695423 588__ $$aDescription based on online resource; title from PDF title page (SpringerLink, viewed Sep. 26, 2013). 000695423 650_0 $$aDegeneration (Pathology) 000695423 650_0 $$aBrain$$xDegeneration. 000695423 7001_ $$aWenning, Gregor K.,$$eeditor of compilation.$$eauthor. 000695423 7001_ $$aFanciulli, Alessandra,$$eeditor of compilation.$$eauthor. 000695423 85280 $$bebk$$hSpringerLink 000695423 85640 $$3SpringerLink$$uhttps://univsouthin.idm.oclc.org/login?url=http://dx.doi.org/10.1007/978-3-7091-0687-7$$zOnline Access 000695423 909CO $$ooai:library.usi.edu:695423$$pGLOBAL_SET 000695423 980__ $$aEBOOK 000695423 980__ $$aBIB 000695423 982__ $$aEbook 000695423 983__ $$aOnline 000695423 994__ $$a92$$bISE