Multiple system atrophy [electronic resource] / Gregor Wenning, Alessandra Fanciulli, editors.

9783709106877 electronic book
3709106877 electronic book
9783709106860

Vienna : Springer, [2013?]

©2014

English

1 online resource (xvi, 198 pages) : color illustrations.

10.1007/978-3-7091-0687-7 doi

RC394.D35 .M85 2013

616.8

This textbook provides a comprehensive monography on multiple system atrophy (MSA), a rare and fatal neurodegenerative disorder that presents with autonomic failure and either parkinsonism (MSA-P) or cerebellar ataxia (MSA-C).The underlying neuropathology of MSA is characterized by striatonigral degeneration (SND), olivopontocerebellar atrophy (OPCA) and unique oligodendroglial cytoplasmic alpha-synuclein inclusions. MSA is therefore classified among the alpha-synucleinopathies such as Parkinson's disease, pure autonomic failure and dementia with Lewy bodies. Over the last decade there have been important advances in early diagnosis, pathogenesis research and clinical trial activity. The monography will cover the entire spectrum ranging from molecular and genetic work to symptomatic and interventional therapies. The book is written for movement disorder clinicians and basic neuroscientists interested in degenerative movement disorders.

Includes index.

Access limited to authorized users.

Description based on online resource; title from PDF title page (SpringerLink, viewed Sep. 26, 2013).

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